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Flights from Charleston to Des Moines
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Cheap flight deals from Charleston to Des Moines Starting at €222

For as little as €222, you can take your next adventure to Des Moines without breaking the bank. Choose between one-way and return tickets from Charleston below.

  • Round-trip
      • CRW06:00
        5h 40m
        1 stop
        DSM10:40
        Thu, Feb 20|Charleston - Des Moines|Delta Air Lines
        DSM05:34
        7h 23m
        1 stop
        CRW13:57
        Wed, Feb 26|Des Moines - Charleston|Delta Air Lines
        €222€596
        63% OFF
        63% OFF
        €596€222

        Choose Delta Air Lines flights from Charleston to Des Moines. The one-way connecting flight with Delta Air Lines departs from Yeager Airport on Thu, Feb 20-Wed, Feb 26, arriving at Des Moines International Airport. One-way Prices start from €222 including taxes and charges.

      • CRW07:05
        4h 28m
        1 stop
        DSM10:33
        Wed, Feb 26|Charleston - Des Moines|United Airlines
        DSM15:15
        4h 38m
        1 stop
        CRW20:53
        Sat, Mar 1|Des Moines - Charleston|United Airlines
        €289€596
        52% OFF
        52% OFF
        €596€289

        Choose United Airlines flights from Charleston to Des Moines. The one-way connecting flight with United Airlines departs from Yeager Airport on Wed, Feb 26-Sat, Mar 1, arriving at Des Moines International Airport. One-way Prices start from €289 including taxes and charges.

      • CRW11:15
        7h 30m
        1 stop
        DSM17:45
        Tue, Mar 11|Charleston - Des Moines|Delta Air Lines
        DSM17:17
        16h 18m
        2 stops
        CRW10:35
        Mon, Mar 17|Des Moines - Charleston|Delta Air Lines
        €314€596
        47% OFF
        47% OFF
        €596€314

        Choose Delta Air Lines flights from Charleston to Des Moines. The one-way connecting flight with Delta Air Lines departs from Yeager Airport on Tue, Mar 11-Mon, Mar 17, arriving at Des Moines International Airport. One-way Prices start from €314 including taxes and charges.

      • CRW07:05
        4h 28m
        1 stop
        DSM10:33
        Thu, Feb 20|Charleston - Des Moines|United Airlines
        DSM11:29
        4h 15m
        1 stop
        CRW16:44
        Wed, Feb 26|Des Moines - Charleston|United Airlines
        €326
        €326

        Choose United Airlines flights from Charleston to Des Moines. The one-way connecting flight with United Airlines departs from Yeager Airport on Thu, Feb 20-Wed, Feb 26, arriving at Des Moines International Airport. One-way Prices start from €326 including taxes and charges.

      • CRW17:30
        4h 53m
        1 stop
        DSM21:23
        Tue, Feb 18|Charleston - Des Moines|United Airlines
        DSM11:29
        4h 15m
        1 stop
        CRW16:44
        Mon, Feb 24|Des Moines - Charleston|United Airlines
        €340
        €340

        Choose United Airlines flights from Charleston to Des Moines. The one-way connecting flight with United Airlines departs from Yeager Airport on Tue, Feb 18-Mon, Feb 24, arriving at Des Moines International Airport. One-way Prices start from €340 including taxes and charges.

      • CRW13:55
        5h 1m
        1 stop
        DSM17:56
        Tue, Mar 11|Charleston - Des Moines|United Airlines
        DSM15:25
        4h 26m
        1 stop
        CRW20:51
        Mon, Mar 17|Des Moines - Charleston|United Airlines
        €364
        €364

        Choose United Airlines flights from Charleston to Des Moines. The one-way connecting flight with United Airlines departs from Yeager Airport on Tue, Mar 11-Mon, Mar 17, arriving at Des Moines International Airport. One-way Prices start from €364 including taxes and charges.

      • CRW17:30
        4h 53m
        1 stop
        DSM21:23
        Sun, Feb 16|Charleston - Des Moines|United Airlines
        DSM11:29
        4h 15m
        1 stop
        CRW16:44
        Sat, Feb 22|Des Moines - Charleston|United Airlines
        €372
        €372

        Choose United Airlines flights from Charleston to Des Moines. The one-way connecting flight with United Airlines departs from Yeager Airport on Sun, Feb 16-Sat, Feb 22, arriving at Des Moines International Airport. One-way Prices start from €372 including taxes and charges.

      • CRW06:00
        5h 40m
        1 stop
        DSM10:40
        Tue, Feb 18|Charleston - Des Moines|Delta Air Lines
        DSM05:34
        7h 23m
        1 stop
        CRW13:57
        Mon, Feb 24|Des Moines - Charleston|Delta Air Lines
        €428
        €428

        Choose Delta Air Lines flights from Charleston to Des Moines. The one-way connecting flight with Delta Air Lines departs from Yeager Airport on Tue, Feb 18-Mon, Feb 24, arriving at Des Moines International Airport. One-way Prices start from €428 including taxes and charges.

      • CRW14:37
        7h 20m
        2 stops
        DSM20:57
        Mon, Feb 17|Charleston - Des Moines|Delta Air Lines
        DSM12:15
        9h 26m
        2 stops
        CRW22:41
        Sun, Feb 23|Des Moines - Charleston|Delta Air Lines
        €435
        €435

        Choose Delta Air Lines flights from Charleston to Des Moines. The one-way connecting flight with Delta Air Lines departs from Yeager Airport on Mon, Feb 17-Sun, Feb 23, arriving at Des Moines International Airport. One-way Prices start from €435 including taxes and charges.

      • CRW06:00
        5h 40m
        1 stop
        DSM10:40
        Mon, Feb 24|Charleston - Des Moines|Delta Air Lines
        DSM11:30
        4h 40m
        1 stop
        CRW17:10
        Thu, Feb 27|Des Moines - Charleston|Delta Air Lines
        €450
        €450

        Choose Delta Air Lines flights from Charleston to Des Moines. The one-way connecting flight with Delta Air Lines departs from Yeager Airport on Mon, Feb 24-Thu, Feb 27, arriving at Des Moines International Airport. One-way Prices start from €450 including taxes and charges.

      • CRW01:00 pm
        3h 5m
        Nonstop
        DSM02:00 pm
        Sat, Feb 22|Charleston - Des Moines|Delta Air Lines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Charleston to Des Moines flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. AA5153

    American Airlines

    05:39

    CRW

    1.3h

    06:59

    DCA

    SMTWTFS
    Search

  2. AA5388

    American Airlines

    10:23

    DCA

    2.9h

    12:18

    DSM

    SMTWTFS

  3. DL3805

    Delta Air Lines

    06:24

    CRW

    1.5h

    07:56

    ATL

    SMTWTFS
    Search

  4. DL2960

    Delta Air Lines

    08:55

    ATL

    2.7h

    10:36

    MSP

    SMTWTFS

  5. DL4998

    Delta Air Lines

    09:00

    MSP

    1.2h

    10:11

    DSM

    SMTWTFS

  6. DL3805

    Delta Air Lines

    06:24

    CRW

    1.5h

    07:56

    ATL

    SMTWTFS
    Search

  7. DL1704

    Delta Air Lines

    09:05

    ATL

    2.2h

    10:16

    DSM

    SMTWTFS

  8. UA5801

    United Airlines

    07:00

    CRW

    2.0h

    07:58

    ORD

    SMTWTFS
    Search

  9. UA301

    United Airlines

    09:05

    ORD

    1.3h

    10:20

    DSM

    SMTWT--

  10. DL4850

    Delta Air Lines

    11:37

    CRW

    1.5h

    13:05

    ATL

    SMTWTFS
    Search

  11. DL2086

    Delta Air Lines

    16:27

    ATL

    2.2h

    17:38

    DSM

    SMTWTFS

  12. UA4644

    United Airlines

    17:33

    CRW

    2.0h

    18:31

    ORD

    SMTWTFS
    Search

  13. UA617

    United Airlines

    19:50

    ORD

    1.6h

    21:23

    DSM

    SMTWTFS

  14. DL5105

    Delta Air Lines

    18:40

    CRW

    1.5h

    20:12

    ATL

    SMTWT-S
    Search

  15. DL1253

    Delta Air Lines

    19:20

    ATL

    2.0h

    21:18

    DTW

    SMTWTFS

  16. DL5087

    Delta Air Lines

    19:55

    DTW

    1.8h

    20:45

    DSM

    SMTWT-S
Find more flights and airlines

When is the cheapest time to fly from Charleston to Des Moines?

These price trend charts carefully monitor and predict how flight prices from Charleston to Des Moines will change. Keep a close eye on them to understand when the best time to buy your tickets is.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Charleston (CRW) to Des Moines (DSM) the cheapest?

    Airlines adjust prices for flights from Charleston to Des Moines based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Charleston (CRW) to Des Moines (DSM) cost?

    According to Trip.com's data, the lowest price is around €452.

  • How many airports are there in Des Moines (DSM)?

    There are 1 airport(s) near Des Moines (DSM): Des Moines International Airport.

How to find a cheap flight from Charleston to Des Moines

If you don’t know some of the key things to look out for when buying flight tickets, prices can often end up sky high or, worse, sold out! We’ve carefully compiled our six most important steps to help ensure you’re getting the best deals when planning your next journey.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | Charleston to Des Moines

Off-season for travelDecember
Peak season for travelSeptember
Flight distance1,085.66 km
Popular airlineAmerican Airlines

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