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Cheap flight deals from Chicago to Sao Tome Island Starting at VND 41,580,515

Discover our range of affordable one-way and round-trip flights from Chicago to Sao Tome Island and kick-start your next adventure today!

  • Round-trip
      • ORD16:18
        18h 57m
        2 stops
        TMS17:15
        Fri, Feb 28|Chicago - Sao Tome Island|Iberia
        TMS19:25
        48h 30m
        2 stops
        ORD13:55
        Sun, Mar 2|Sao Tome Island - Chicago|TAP Air Portugal
        VND 41,580,515VND 156,303,893
        73% OFF
        73% OFF
        VND 156,303,893VND 41,580,515

        Choose Iberia flights from Chicago to Sao Tome Island. The one-way connecting flight with Iberia departs from O'Hare International Airport on Fri, Feb 28-Sun, Mar 2, arriving at São Tomé International Airport. One-way Prices start from VND 41,580,515 including taxes and charges.

      • ORD15:35
        19h 40m
        2 stops
        TMS17:15
        Fri, Feb 28|Chicago - Sao Tome Island|United Airlines
        TMS19:25
        30h 40m
        2 stops
        ORD20:05
        Sun, Mar 2|Sao Tome Island - Chicago|TAP Air Portugal
        VND 44,051,165VND 156,303,893
        72% OFF
        72% OFF
        VND 156,303,893VND 44,051,165

        Choose United Airlines flights from Chicago to Sao Tome Island. The one-way connecting flight with United Airlines departs from O'Hare International Airport on Fri, Feb 28-Sun, Mar 2, arriving at São Tomé International Airport. One-way Prices start from VND 44,051,165 including taxes and charges.

      • ORD11:53
        23h 22m
        2 stops
        TMS17:15
        Fri, Feb 28|Chicago - Sao Tome Island|TAP Air Portugal
        TMS19:25
        29h 55m
        2 stops
        ORD19:20
        Sun, Mar 2|Sao Tome Island - Chicago|TAP Air Portugal
        VND 59,085,334VND 156,303,893
        62% OFF
        62% OFF
        VND 156,303,893VND 59,085,334

        Choose TAP Air Portugal flights from Chicago to Sao Tome Island. The one-way connecting flight with TAP Air Portugal departs from O'Hare International Airport on Fri, Feb 28-Sun, Mar 2, arriving at São Tomé International Airport. One-way Prices start from VND 59,085,334 including taxes and charges.

      • ORD20:05
        40h 10m
        2 stops
        TMS17:15
        Thu, Mar 20|Chicago - Sao Tome Island|Swiss Airlines
        TMS19:25
        46h 45m
        2 stops
        ORD12:10
        Fri, Mar 28|Sao Tome Island - Chicago|TAP Air Portugal
        VND 60,725,425
        VND 60,725,425

        Choose Swiss Airlines flights from Chicago to Sao Tome Island. The one-way connecting flight with Swiss Airlines departs from O'Hare International Airport on Thu, Mar 20-Fri, Mar 28, arriving at São Tomé International Airport. One-way Prices start from VND 60,725,425 including taxes and charges.

      • ORD16:55
        43h 20m
        2 stops
        TMS17:15
        Thu, Mar 20|Chicago - Sao Tome Island|Lufthansa
        TMS19:25
        46h 45m
        2 stops
        ORD12:10
        Fri, Mar 28|Sao Tome Island - Chicago|TAP Air Portugal
        VND 61,345,716
        VND 61,345,716

        Choose Lufthansa flights from Chicago to Sao Tome Island. The one-way connecting flight with Lufthansa departs from O'Hare International Airport on Thu, Mar 20-Fri, Mar 28, arriving at São Tomé International Airport. One-way Prices start from VND 61,345,716 including taxes and charges.

      • ORD12:55
        47h 20m
        2 stops
        TMS17:15
        Thu, Mar 20|Chicago - Sao Tome Island|Turkish Airlines
        TMS19:25
        43h 25m
        2 stops
        ORD09:50
        Fri, Mar 28|Sao Tome Island - Chicago|TAP Air Portugal
        VND 62,603,820
        VND 62,603,820

        Choose Turkish Airlines flights from Chicago to Sao Tome Island. The one-way connecting flight with Turkish Airlines departs from O'Hare International Airport on Thu, Mar 20-Fri, Mar 28, arriving at São Tomé International Airport. One-way Prices start from VND 62,603,820 including taxes and charges.

      • ORD17:15
        43h
        2 stops
        TMS17:15
        Thu, Mar 20|Chicago - Sao Tome Island|TAP Air Portugal
        TMS19:25
        42h
        2 stops
        ORD08:25
        Fri, Mar 28|Sao Tome Island - Chicago|TAP Air Portugal
        VND 63,409,848
        VND 63,409,848

        Choose TAP Air Portugal flights from Chicago to Sao Tome Island. The one-way connecting flight with TAP Air Portugal departs from O'Hare International Airport on Thu, Mar 20-Fri, Mar 28, arriving at São Tomé International Airport. One-way Prices start from VND 63,409,848 including taxes and charges.

      • ORD19:00
        41h 15m
        2 stops
        TMS17:15
        Thu, Mar 20|Chicago - Sao Tome Island|United Airlines
        TMS19:25
        41h 5m
        2 stops
        ORD07:30
        Fri, Mar 28|Sao Tome Island - Chicago|TAP Air Portugal
        VND 64,738,041
        VND 64,738,041

        Choose United Airlines flights from Chicago to Sao Tome Island. The one-way connecting flight with United Airlines departs from O'Hare International Airport on Thu, Mar 20-Fri, Mar 28, arriving at São Tomé International Airport. One-way Prices start from VND 64,738,041 including taxes and charges.

      • ORD08:11
        28h 44m
        2 stops
        TMS17:55
        Thu, Mar 20|Chicago - Sao Tome Island|American Airlines
        TMS19:25
        43h 35m
        2 stops
        ORD10:00
        Fri, Mar 28|Sao Tome Island - Chicago|TAP Air Portugal
        VND 67,369,897
        VND 67,369,897

        Choose American Airlines flights from Chicago to Sao Tome Island. The one-way connecting flight with American Airlines departs from O'Hare International Airport on Thu, Mar 20-Fri, Mar 28, arriving at São Tomé International Airport. One-way Prices start from VND 67,369,897 including taxes and charges.

      • ORD19:30
        40h 45m
        2 stops
        TMS17:15
        Thu, Mar 20|Chicago - Sao Tome Island|Finnair
        TMS19:25
        27h 15m
        2 stops
        ORD17:40
        Fri, Mar 28|Sao Tome Island - Chicago|TAP Air Portugal
        VND 74,207,114
        VND 74,207,114

        Choose Finnair flights from Chicago to Sao Tome Island. The one-way connecting flight with Finnair departs from O'Hare International Airport on Thu, Mar 20-Fri, Mar 28, arriving at São Tomé International Airport. One-way Prices start from VND 74,207,114 including taxes and charges.

      • CHI01:00 pm
        3h 5m
        Nonstop
        TMS02:00 pm
        Wed, Feb 26|Chicago - Sao Tome Island|Iberia
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Chicago to Sao Tome Island flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. AA2345

    American Airlines

    07:50

    ORD

    1.9h

    10:44

    DCA

    SMTWTFS
    Search

  2. TP232

    TAP Air Portugal

    17:45

    IAD

    7.3h

    06:05

    LIS

    -M---F-

  3. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.7h

    17:35

    TMS

    --T-T-S

  4. AA3056

    American Airlines

    10:07

    ORD

    3.2h

    14:17

    MIA

    SMTWTFS
    Search

  5. TP224

    TAP Air Portugal

    16:35

    MIA

    8.3h

    05:50

    LIS

    S-TWTFS

  6. TP1531

    TAP Air Portugal

    11:40

    LIS

    6.7h

    17:20

    TMS

    -----F-

  7. TP8481

    TAP Air Portugal

    10:36

    ORD

    2.3h

    13:53

    EWR

    SMTWTFS
    Search

  8. TP202

    TAP Air Portugal

    17:35

    EWR

    6.9h

    05:30

    LIS

    SMTW-F-

  9. TP1531

    TAP Air Portugal

    11:40

    LIS

    6.7h

    17:20

    TMS

    -----F-

  10. UA702

    United Airlines

    15:35

    ORD

    2.3h

    18:50

    EWR

    SMTWTFS
    Search

  11. UA064

    United Airlines

    20:35

    EWR

    6.8h

    08:20

    LIS

    SMTWTFS

  12. TP1531

    TAP Air Portugal

    11:40

    LIS

    6.7h

    17:20

    TMS

    -----F-

  13. IB4351

    Iberia

    16:18

    ORD

    2.0h

    19:17

    PHL

    S--WT-S
    Search

  14. IB4918

    Iberia

    21:15

    PHL

    6.8h

    09:05

    LIS

    SMTWTFS

  15. TP1531

    TAP Air Portugal

    11:40

    LIS

    6.7h

    17:20

    TMS

    -----F-

  16. IB342

    Iberia

    16:30

    ORD

    8.4h

    07:55

    MAD

    SMTWTFS
    Search

  17. IB1141

    Iberia

    11:25

    MAD

    1.4h

    11:50

    LIS

    SMTWTFS

  18. TP1531

    TAP Air Portugal

    11:40

    LIS

    6.7h

    17:20

    TMS

    -----F-

  19. AY5760

    Finnair

    17:35

    ORD

    7.8h

    07:25

    LHR

    SMTWTFS
    Search

  20. AY5895

    Finnair

    13:30

    LHR

    2.8h

    16:20

    LIS

    SMTWTF-

  21. TP1531

    TAP Air Portugal

    11:40

    LIS

    6.7h

    17:20

    TMS

    -----F-

  22. UA953

    United Airlines

    17:50

    ORD

    8.8h

    09:40

    MUC

    SMTWTFS
    Search

  23. LH1778

    Lufthansa

    11:00

    MUC

    3.3h

    13:20

    LIS

    SMTWTFS

  24. TP1531

    TAP Air Portugal

    11:40

    LIS

    6.7h

    17:20

    TMS

    -----F-

  25. LX009

    Swiss Airlines

    19:05

    ORD

    8.8h

    10:50

    ZRH

    SMTWTFS
    Search

  26. LX2084

    Swiss Airlines

    12:35

    ZRH

    3.0h

    14:35

    LIS

    SMTWTFS

  27. TP1531

    TAP Air Portugal

    11:40

    LIS

    6.7h

    17:20

    TMS

    -----F-

  28. BA296

    British Airways

    21:15

    ORD

    7.8h

    11:00

    LHR

    SMTWTFS
    Search

  29. BA502

    British Airways

    15:05

    LHR

    2.8h

    17:55

    LIS

    SMTWTFS

  30. TP1531

    TAP Air Portugal

    11:40

    LIS

    6.7h

    17:20

    TMS

    -----F-
Find more flights and airlines

When is the cheapest time to fly from Chicago to Sao Tome Island?

Explore the best time to buy affordable tickets to Sao Tome Island with our price trend chart, which predicts how flight prices will change in the coming weeks from previous data.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Chicago (CHI) to Sao Tome Island (TMS) the cheapest?

    Airlines adjust prices for flights from Chicago to Sao Tome Island based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Chicago (CHI) to Sao Tome Island (TMS) cost?

    According to Trip.com's data, the lowest price is around VND 28,708,603.

  • What is the transportation method from the main airport to downtown in Sao Tome Island?

    • The distance from São Tomé International Airport to downtown is about 5 km, by taxi about 20 minutes.

  • How many airports are there in Sao Tome Island (TMS)?

    There are 1 airport(s) near Sao Tome Island (TMS): São Tomé International Airport.

How to find a cheap flight from Chicago to Sao Tome Island

If you leave it until the last minute and forget to check some of the key information when booking tickets, prices can often end up skyrocketing. Below, you can find our top tips for getting the best value flights – from changing dates to chasing deals, there are plenty ways to keep your next trip affordable.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | Chicago to Sao Tome Island

Off-season for travelFebruary
Peak season for travelJanuary
Flight distance10,339.58 km
Popular airlineAmerican Airlines

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