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Cheap flight deals from Des Moines to Brussels Starting at AED 1,790

Whether you’re going for a one-way or round-trip to Brussels, we’ve got you covered! Check out these different flight options from Des Moines below.

  • One way
  • Round-trip
      • DSM08:10
        17h 45m
        1 stop
        BRU07:55
        Sun, Mar 9|Des Moines - Brussels|United Airlines
        AED 1,790AED 3,184
        44% OFF
        44% OFF
        AED 3,184AED 1,790

        Choose United Airlines flights from Des Moines to Brussels. The one-way connecting flight with United Airlines departs from Des Moines International Airport on Sun, Mar 9, arriving at Brussels National Airport. One-way Prices start from AED 1,790 including taxes and charges.

      • DSM08:00
        17h 55m
        1 stop
        BRU08:55
        Mon, Mar 3|Des Moines - Brussels|United Airlines
        AED 1,793AED 3,184
        44% OFF
        44% OFF
        AED 3,184AED 1,793

        Choose United Airlines flights from Des Moines to Brussels. The one-way connecting flight with United Airlines departs from Des Moines International Airport on Mon, Mar 3, arriving at Brussels National Airport. One-way Prices start from AED 1,793 including taxes and charges.

      • DSM08:00
        17h 55m
        1 stop
        BRU08:55
        Wed, Feb 26|Des Moines - Brussels|United Airlines
        AED 1,797AED 3,184
        44% OFF
        44% OFF
        AED 3,184AED 1,797

        Choose United Airlines flights from Des Moines to Brussels. The one-way connecting flight with United Airlines departs from Des Moines International Airport on Wed, Feb 26, arriving at Brussels National Airport. One-way Prices start from AED 1,797 including taxes and charges.

      • DSM15:28
        10h 27m
        1 stop
        BRU07:55
        Wed, Mar 26|Des Moines - Brussels|United Airlines
        AED 1,848
        AED 1,848

        Choose United Airlines flights from Des Moines to Brussels. The one-way connecting flight with United Airlines departs from Des Moines International Airport on Wed, Mar 26, arriving at Brussels National Airport. One-way Prices start from AED 1,848 including taxes and charges.

      • DSM08:50
        18h 10m
        1 stop
        BRU09:00
        Sun, Mar 9|Des Moines - Brussels|Delta Air Lines
        AED 1,867
        AED 1,867

        Choose Delta Air Lines flights from Des Moines to Brussels. The one-way connecting flight with Delta Air Lines departs from Des Moines International Airport on Sun, Mar 9, arriving at Brussels National Airport. One-way Prices start from AED 1,867 including taxes and charges.

      • DSM17:17
        33h 43m
        1 stop
        BRU09:00
        Tue, Mar 25|Des Moines - Brussels|Delta Air Lines
        AED 1,869
        AED 1,869

        Choose Delta Air Lines flights from Des Moines to Brussels. The one-way connecting flight with Delta Air Lines departs from Des Moines International Airport on Tue, Mar 25, arriving at Brussels National Airport. One-way Prices start from AED 1,869 including taxes and charges.

      • DSM07:20
        19h 40m
        1 stop
        BRU09:00
        Wed, Mar 26|Des Moines - Brussels|Delta Air Lines
        AED 1,916
        AED 1,916

        Choose Delta Air Lines flights from Des Moines to Brussels. The one-way connecting flight with Delta Air Lines departs from Des Moines International Airport on Wed, Mar 26, arriving at Brussels National Airport. One-way Prices start from AED 1,916 including taxes and charges.

      • DSM08:10
        17h 45m
        1 stop
        BRU07:55
        Tue, Mar 25|Des Moines - Brussels|United Airlines
        AED 1,916
        AED 1,916

        Choose United Airlines flights from Des Moines to Brussels. The one-way connecting flight with United Airlines departs from Des Moines International Airport on Tue, Mar 25, arriving at Brussels National Airport. One-way Prices start from AED 1,916 including taxes and charges.

      • DSM08:00
        17h 55m
        1 stop
        BRU08:55
        Fri, Feb 28|Des Moines - Brussels|United Airlines
        AED 1,980
        AED 1,980

        Choose United Airlines flights from Des Moines to Brussels. The one-way connecting flight with United Airlines departs from Des Moines International Airport on Fri, Feb 28, arriving at Brussels National Airport. One-way Prices start from AED 1,980 including taxes and charges.

      • DSM15:25
        10h 30m
        1 stop
        BRU07:55
        Fri, Mar 28|Des Moines - Brussels|United Airlines
        AED 2,045
        AED 2,045

        Choose United Airlines flights from Des Moines to Brussels. The one-way connecting flight with United Airlines departs from Des Moines International Airport on Fri, Mar 28, arriving at Brussels National Airport. One-way Prices start from AED 2,045 including taxes and charges.

      • DSM01:00 pm
        3h 5m
        Nonstop
        BRU02:00 pm
        Tue, Mar 4|Des Moines - Brussels|United Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Des Moines to Brussels flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. UA1363

    United Airlines

    08:00

    DSM

    1.5h

    09:28

    ORD

    SMTWTFS
    Search

  2. UA1869

    United Airlines

    11:15

    ORD

    1.9h

    14:11

    IAD

    ---W---

  3. UA950

    United Airlines

    17:45

    IAD

    7.5h

    07:15

    BRU

    SMTWTFS

  4. UA1363

    United Airlines

    08:00

    DSM

    1.5h

    09:28

    ORD

    SMTWTFS
    Search

  5. UA1097

    United Airlines

    11:15

    ORD

    2.0h

    14:13

    DCA

    SMTWTFS

  6. UA950

    United Airlines

    17:45

    IAD

    7.5h

    07:15

    BRU

    SMTWTFS

  7. LH8763

    Lufthansa

    11:20

    DSM

    1.6h

    12:55

    ORD

    SMT-TFS
    Search

  8. LH7949

    Lufthansa

    17:55

    ORD

    8.1h

    09:00

    BRU

    SMTWTFS

  9. UA1373

    United Airlines

    11:29

    DSM

    1.5h

    12:57

    ORD

    SMTWT--
    Search

  10. UA972

    United Airlines

    17:55

    ORD

    8.1h

    09:00

    BRU

    SMTWTFS

  11. SK3231

    Scandinavian Airlines

    14:14

    DSM

    2.2h

    17:25

    ATL

    S-T-TF-
    Search

  12. SK930

    Scandinavian Airlines

    19:55

    ATL

    8.9h

    10:50

    CPH

    S-T-TF-

  13. SK1593

    Scandinavian Airlines

    12:45

    CPH

    1.5h

    14:15

    BRU

    SMTWT-S

  14. UA4393

    United Airlines

    15:15

    DSM

    1.5h

    16:45

    ORD

    SMTWTFS
    Search

  15. UA972

    United Airlines

    17:55

    ORD

    8.1h

    09:00

    BRU

    SMTWTFS

  16. KL7343

    KLM

    16:20

    DSM

    1.2h

    17:32

    MSP

    SMTWTFS
    Search

  17. KL6064

    KLM

    15:50

    MSP

    8.1h

    06:55

    AMS

    SMTWTFS

  18. KL1703

    KLM

    09:25

    AMS

    0.8h

    10:10

    BRU

    SMTWTFS

  19. KL5762

    KLM

    18:30

    DSM

    2.2h

    21:40

    ATL

    SMTWTFS
    Search

  20. KL622

    KLM

    22:40

    ATL

    8.5h

    13:10

    AMS

    SMTWTFS

  21. KL1705

    KLM

    13:50

    AMS

    0.8h

    14:35

    BRU

    SMTWTFS

  22. LH7635

    Lufthansa

    18:45

    DSM

    1.6h

    20:20

    ORD

    SMTWTFS
    Search

  23. LH435

    Lufthansa

    21:40

    ORD

    8.5h

    13:10

    MUC

    SMTWTFS

  24. LH5626

    Lufthansa

    14:55

    MUC

    1.3h

    16:15

    BRU

    SMTWTFS

  25. LH7635

    Lufthansa

    18:45

    DSM

    1.6h

    20:20

    ORD

    SMTWTFS
    Search

  26. LH435

    Lufthansa

    21:40

    ORD

    8.5h

    13:10

    MUC

    SMTWTFS

  27. LH2288

    Lufthansa

    14:40

    MUC

    1.4h

    16:05

    BRU

    SMTWTFS
Find more flights and airlines

When is the cheapest time to fly from Des Moines to Brussels?

Price trend charts are a great way of tracking how much your flights cost in the lead up to departure and can help you choose when to book your tickets. See how prices to Brussels from Des Moines have changed and are set to move below.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Des Moines (DSM) to Brussels (BRU) the cheapest?

    Airlines adjust prices for flights from Des Moines to Brussels based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Des Moines (DSM) to Brussels (BRU) cost?

    According to Trip.com's data, the lowest price is around AED 7,281.

  • What is the transportation method from the main airport to downtown in Brussels?

    • The distance from Brussels National Airport to downtown is about 10 km, by taxi about 30 minutes.
    • The distance from Brussels South Charleroi Airport to downtown is about 43 km, by taxi about 1 hour.

  • How many airports are there in Brussels (BRU)?

    There are 2 airport(s) near Brussels (BRU): Brussels National Airport and Brussels South Charleroi Airport.

How to find a cheap flight from Des Moines to Brussels

Understanding the common pitfalls when booking your flight tickets can help you save massively when it comes time to fly. We’ve listed our six essential steps to keep in mind when you’re booking flight tickets to help you find the best price.
1
Being flexible with your dates to get the cheapest Des Moines to Brussels ticket.
Tap "Date" on flight search bar to scan through the calender for Des Moines to Brussels airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Sun, Mar 9 at AED 1790 for one-way flights.
2
Compare cheap Des Moines to Brussels flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from Des Moines to Brussels. The cheapest airline operating is United Airlines.
3
Set up a Price Alert
By setting up a Price Alert for your Des Moines to Brussels route, you can easily track the price of your airline tickets from without manually checking every day.
4
Don't miss cheap Des Moines to Brussels flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights. If registering a free membership, you can receive more deals for your flights.
5
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
6
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com and search for cheap flight tickets from Des Moines to Brussels to get exclusive deals for you.

Flight Info | Des Moines to Brussels

Cheapest direct flight priceAED 1,790
Off-season for travelMarch
Peak season for travelDecember
Flight distance7,049.89 km
Popular airlineAmerican Airlines

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