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Flights from Des Moines to Panama City

Cheap flight deals from Des Moines to Panama City

We've found these cheap flights for you. You can book one-way or round-trip flight tickets.

  • Round-trip
  • One way

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

When is the cheapest time to fly from Des Moines to Panama City?

We monitor flight fares to help you find the best deals effortlessly

Cheapest flights
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  • 13 20
  • 20 27

  • May

    27 4
  • 4 11
  • 11 18
  • 18 25

  • Jun

    25 1
  • 1 8
  • 8 15
  • 15 22
  • 22 29

  • Jul

    29 6
Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Des Moines (DSM) to Panama City (ECP) the cheapest?

    Airlines adjust prices for flights from Des Moines to Panama City based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Des Moines (DSM) to Panama City (ECP) cost?

    According to Trip.com's data, the lowest price is around AED 2,376.

  • How many airports are there in Panama City (ECP)?

    There are 1 airport(s) near Panama City (ECP): Northwest Florida Beaches International Airport.

How to find a cheap flight from Des Moines to Panama City

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Des Moines to Panama City. Book your flights at the right time and save more.
1
Being flexible with your dates to get the cheapest Des Moines to Panama City ticket.
Tap "Date" on flight search bar to scan through the calender for Des Moines to Panama City airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Tue, Apr 29 at AED 488 for one-way flights.
2
Compare cheap Des Moines to Panama City flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from Des Moines to Panama City. The cheapest airline operating is Delta Air Lines.
3
Set up a Price Alert
By setting up a Price Alert for your Des Moines to Panama City route, you can easily track the price of your airline tickets from without manually checking every day.
4
Don't miss cheap Des Moines to Panama City flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights. If registering a free membership, you can receive more deals for your flights.
5
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
6
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com and search for cheap flight tickets from Des Moines to Panama City to get exclusive deals for you.

Flight Info | Des Moines to Panama City

Cheapest one-way flight price AED 487
Off-season for travel May
Peak season for travel January
Flight distance 1,452.29 km
Popular airline Delta Air Lines

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