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Flights from Des Moines to Panama City
Cheap flight deals from Des Moines to Panama City
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
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Round-trip
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One way
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DSM 15:2024h 52m1 stopsPTY 16:12Des Moines - Panama City | Fri, May 2 | United AirlinesPTY 07:5514h 50m1 stopsDSM 22:45Panama City - Des Moines | Fri, May 9 | United AirlinesAED 1,394 AED 1,63615% OFF15% OFFAED 1,636 AED 1,394
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DSM 05:457h 10m1 stopsPTY 12:55Des Moines - Panama City | Fri, Apr 18 | Delta Air LinesPTY 14:208h 18m1 stopsDSM 22:38Panama City - Des Moines | Fri, Apr 25 | Delta Air LinesAED 1,397 AED 1,63615% OFF15% OFFAED 1,636 AED 1,397
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DSM 15:1225h1 stopsPTY 16:12Des Moines - Panama City | Fri, Apr 18 | United AirlinesPTY 10:0028h 31m1 stopsDSM 14:31Panama City - Des Moines | Fri, Apr 25 | United AirlinesAED 1,400 AED 1,63614% OFF14% OFFAED 1,636 AED 1,400
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DSM 18:2525h 5m1 stopsPTY 19:30Des Moines - Panama City | Fri, May 2 | Delta Air LinesPTY 14:138h 17m1 stopsDSM 22:30Panama City - Des Moines | Fri, May 9 | Delta Air LinesAED 1,40314% OFFAED 1,636 AED 1,403
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DSM 15:2022h 54m1 stopsPTY 14:14Des Moines - Panama City | Fri, May 9 | United AirlinesPTY 07:5514h 50m1 stopsDSM 22:45Panama City - Des Moines | Fri, May 16 | United AirlinesAED 1,40314% OFFAED 1,636 AED 1,403
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DSM 08:0030h 14m1 stopsPTY 14:14Des Moines - Panama City | Sat, May 3 | United AirlinesPTY 07:5514h 50m1 stopsDSM 22:45Panama City - Des Moines | Sat, May 10 | United AirlinesAED 1,40814% OFFAED 1,636 AED 1,408
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DSM 15:1225h1 stopsPTY 16:12Des Moines - Panama City | Mon, Apr 21 | United AirlinesPTY 07:5514h 50m1 stopsDSM 22:45Panama City - Des Moines | Thu, Apr 24 | United AirlinesAED 1,42713% OFFAED 1,636 AED 1,427
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DSM 15:2022h 54m1 stopsPTY 14:14Des Moines - Panama City | Tue, May 6 | United AirlinesPTY 07:5514h 50m1 stopsDSM 22:45Panama City - Des Moines | Fri, May 9 | United AirlinesAED 1,42713% OFFAED 1,636 AED 1,427
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DSM 15:1225h1 stopsPTY 16:12Des Moines - Panama City | Sat, Apr 19 | United AirlinesPTY 10:0012h 45m1 stopsDSM 22:45Panama City - Des Moines | Sat, Apr 26 | United AirlinesAED 1,45211% OFFAED 1,636 AED 1,452
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DSM 08:0010h 37m1 stopsPTY 18:37Des Moines - Panama City | Wed, Apr 30 | United AirlinesPTY 07:5514h 50m1 stopsDSM 22:45Panama City - Des Moines | Wed, May 7 | United AirlinesAED 1,45611% OFFAED 1,636 AED 1,456
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DSM 13:0017h 25m1 stopsPTY Invalid DateDes Moines - Panama City | Sat, Apr 19 | Normal AirlinePTY 15:006hNonstopDSM 16:00Panama City - Des Moines | Mon, Apr 21 | Normal AirlineFind More FlightsFind More Flights
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DSM 18:3518h 13m1 stopsPTY 12:48Des Moines - Panama City | Tue, May 20 | Delta Air LinesAED 605 AED 71615% OFF15% OFFAED 716 AED 605
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DSM 08:0010h 37m1 stopsPTY 18:37Des Moines - Panama City | Thu, Apr 24 | United AirlinesAED 608 AED 71615% OFF15% OFFAED 716 AED 608
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DSM 08:008h 12m1 stopsPTY 16:12Des Moines - Panama City | Tue, Apr 22 | United AirlinesAED 617 AED 71614% OFF14% OFFAED 716 AED 617
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DSM 08:008h 12m1 stopsPTY 16:12Des Moines - Panama City | Tue, May 6 | United AirlinesAED 61714% OFFAED 716 AED 617
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DSM 08:0010h 37m1 stopsPTY 18:37Des Moines - Panama City | Mon, Apr 21 | United AirlinesAED 62213% OFFAED 716 AED 622
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DSM 08:008h 12m1 stopsPTY 16:12Des Moines - Panama City | Fri, May 16 | United AirlinesAED 62213% OFFAED 716 AED 622
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DSM 08:008h 12m1 stopsPTY 16:12Des Moines - Panama City | Mon, May 5 | United AirlinesAED 62213% OFFAED 716 AED 622
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DSM 08:008h 12m1 stopsPTY 16:12Des Moines - Panama City | Sat, Apr 26 | United AirlinesAED 63312% OFFAED 716 AED 633
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DSM 05:457h 10m1 stopsPTY 12:55Des Moines - Panama City | Mon, Apr 21 | Delta Air LinesAED 63511% OFFAED 716 AED 635
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DSM 08:008h 12m1 stopsPTY 16:12Des Moines - Panama City | Tue, May 20 | United AirlinesAED 63711% OFFAED 716 AED 637
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DSM 13:0017h 25m1 stopsPTY Invalid DateDes Moines - Panama City | Sat, Apr 19 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
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Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Frequently Asked Questions
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When are flight tickets from Des Moines (DSM) to Panama City (PTY) the cheapest?
Airlines adjust prices for flights from Des Moines to Panama City based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much do flights from Des Moines (DSM) to Panama City (PTY) cost?
According to Trip.com's data, the lowest price is around AED 2,384. -
How many airports are there in Panama City (PTY)?
There are 2 airport(s) near Panama City (PTY): Albrook "Marcos A. Gelabert" International Airport and Tocumen International Airport.
How to find a cheap flight from Des Moines to Panama City
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Des Moines to Panama City. Book your flights at the right time and save more.
Being flexible with your dates to get the cheapest Des Moines to Panama City ticket.
Tap "Date" on flight search bar to scan through the calender for Des Moines to Panama City airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Tue, May 20 at AED 605 for one-way flights.
Compare cheap Des Moines to Panama City flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from Des Moines to Panama City. The cheapest airline operating is Delta Air Lines.
Set up a Price Alert
By setting up a Price Alert for your Des Moines to Panama City route, you can easily track the price of your airline tickets from without manually checking every day.
Don't miss cheap Des Moines to Panama City flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights. If registering a free membership, you can receive more deals for your flights.
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com and search for cheap flight tickets from Des Moines to Panama City to get exclusive deals for you.
Flight Info | Des Moines to Panama City
Cheapest one-way flight price | AED 604 |
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Off-season for travel | April |
Peak season for travel | March |
Flight distance | 3,877.9 km |
Popular airline | American Airlines |
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