App
Customer Support
PHP
Find Bookings
Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Cheap flight deals from Des Moines to Prague Starting at PHP 29,612

For as little as PHP 29,612, you can take your next adventure to Prague without breaking the bank. Choose between one-way and return tickets from Des Moines below.

  • One way
  • Round-trip
      • DSM18:45
        36h 25m
        2 stops
        PRG13:10
        Sat, Mar 15|Des Moines - Prague|United Airlines
        PHP 29,612PHP 41,382
        28% OFF
        28% OFF
        PHP 41,382PHP 29,612

        Choose United Airlines flights from Des Moines to Prague. The one-way connecting flight with United Airlines departs from Des Moines International Airport on Sat, Mar 15, arriving at Vaclav Havel Airport. One-way Prices start from PHP 29,612 including taxes and charges.

      • DSM05:45
        32h 30m
        2 stops
        PRG20:15
        Tue, Mar 25|Des Moines - Prague|Virgin Atlantic
        PHP 30,276PHP 41,382
        27% OFF
        27% OFF
        PHP 41,382PHP 30,276

        Choose Virgin Atlantic flights from Des Moines to Prague. The one-way connecting flight with Virgin Atlantic departs from Des Moines International Airport on Tue, Mar 25, arriving at Vaclav Havel Airport. One-way Prices start from PHP 30,276 including taxes and charges.

      • DSM18:30
        19h 45m
        2 stops
        PRG20:15
        Tue, Mar 25|Des Moines - Prague|Delta Air Lines
        PHP 30,451PHP 41,382
        26% OFF
        26% OFF
        PHP 41,382PHP 30,451

        Choose Delta Air Lines flights from Des Moines to Prague. The one-way connecting flight with Delta Air Lines departs from Des Moines International Airport on Tue, Mar 25, arriving at Vaclav Havel Airport. One-way Prices start from PHP 30,451 including taxes and charges.

      • DSM11:35
        26h 40m
        2 stops
        PRG20:15
        Tue, Mar 25|Des Moines - Prague|United Airlines
        PHP 30,475
        PHP 30,475

        Choose United Airlines flights from Des Moines to Prague. The one-way connecting flight with United Airlines departs from Des Moines International Airport on Tue, Mar 25, arriving at Vaclav Havel Airport. One-way Prices start from PHP 30,475 including taxes and charges.

      • DSM09:10
        29h
        2 stops
        PRG21:10
        Tue, Mar 4|Des Moines - Prague|United Airlines
        PHP 30,515
        PHP 30,515

        Choose United Airlines flights from Des Moines to Prague. The one-way connecting flight with United Airlines departs from Des Moines International Airport on Tue, Mar 4, arriving at Vaclav Havel Airport. One-way Prices start from PHP 30,515 including taxes and charges.

      • DSM09:10
        23h 55m
        2 stops
        PRG16:05
        Wed, Feb 26|Des Moines - Prague|United Airlines
        PHP 30,651
        PHP 30,651

        Choose United Airlines flights from Des Moines to Prague. The one-way connecting flight with United Airlines departs from Des Moines International Airport on Wed, Feb 26, arriving at Vaclav Havel Airport. One-way Prices start from PHP 30,651 including taxes and charges.

      • DSM13:35
        20h 30m
        2 stops
        PRG16:05
        Sun, Mar 9|Des Moines - Prague|United Airlines
        PHP 30,659
        PHP 30,659

        Choose United Airlines flights from Des Moines to Prague. The one-way connecting flight with United Airlines departs from Des Moines International Airport on Sun, Mar 9, arriving at Vaclav Havel Airport. One-way Prices start from PHP 30,659 including taxes and charges.

      • DSM07:20
        31h 20m
        2 stops
        PRG20:40
        Mon, Mar 17|Des Moines - Prague|Delta Air Lines
        PHP 30,747
        PHP 30,747

        Choose Delta Air Lines flights from Des Moines to Prague. The one-way connecting flight with Delta Air Lines departs from Des Moines International Airport on Mon, Mar 17, arriving at Vaclav Havel Airport. One-way Prices start from PHP 30,747 including taxes and charges.

      • DSM06:52
        31h 23m
        2 stops
        PRG20:15
        Mon, Mar 24|Des Moines - Prague|Virgin Atlantic
        PHP 30,843
        PHP 30,843

        Choose Virgin Atlantic flights from Des Moines to Prague. The one-way connecting flight with Virgin Atlantic departs from Des Moines International Airport on Mon, Mar 24, arriving at Vaclav Havel Airport. One-way Prices start from PHP 30,843 including taxes and charges.

      • DSM08:10
        30h 5m
        2 stops
        PRG20:15
        Mon, Mar 24|Des Moines - Prague|United Airlines
        PHP 31,043
        PHP 31,043

        Choose United Airlines flights from Des Moines to Prague. The one-way connecting flight with United Airlines departs from Des Moines International Airport on Mon, Mar 24, arriving at Vaclav Havel Airport. One-way Prices start from PHP 31,043 including taxes and charges.

      • DSM01:00 pm
        3h 5m
        Nonstop
        PRG02:00 pm
        Sat, Mar 1|Des Moines - Prague|United Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Des Moines to Prague flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. AF2886

    Air France

    10:15

    DSM

    1.9h

    13:08

    DTW

    SMTWT-S
    Search

  2. AF3605

    Air France

    17:50

    DTW

    8.0h

    07:50

    CDG

    SMTWTFS

  3. AF1382

    Air France

    10:05

    CDG

    1.7h

    11:45

    PRG

    SMTWTFS

  4. DL5058

    Delta Air Lines

    10:15

    DSM

    1.9h

    13:08

    DTW

    SMTWT-S
    Search

  5. DL132

    Delta Air Lines

    16:15

    DTW

    8.8h

    06:00

    AMS

    SMTWTFS

  6. DL9532

    Delta Air Lines

    06:55

    AMS

    1.4h

    08:20

    PRG

    SMTWTFS

  7. AF2483

    Air France

    11:04

    DSM

    2.2h

    14:16

    ATL

    SMTWTFS
    Search

  8. AF031

    Air France

    16:30

    ATL

    8.5h

    07:00

    CDG

    SMTWTFS

  9. AF1382

    Air France

    10:05

    CDG

    1.7h

    11:45

    PRG

    SMTWTFS

  10. AF2483

    Air France

    11:04

    DSM

    2.2h

    14:16

    ATL

    SMTWTFS
    Search

  11. AF6695

    Air France

    16:50

    ATL

    8.1h

    05:55

    AMS

    SMTWTFS

  12. U27925

    easyJet

    17:35

    AMS

    1.5h

    19:05

    PRG

    ---WT--

  13. VS1508

    Virgin Atlantic

    12:20

    DSM

    1.1h

    13:29

    MSP

    SMTWTFS
    Search

  14. VS3934

    Virgin Atlantic

    15:50

    MSP

    8.1h

    06:55

    AMS

    SMTWTFS

  15. U27925

    easyJet

    17:35

    AMS

    1.5h

    19:05

    PRG

    ---WT--

  16. KL7341

    KLM

    12:30

    DSM

    1.8h

    15:15

    DTW

    SMTWTFS
    Search

  17. KL6018

    KLM

    16:25

    DTW

    7.6h

    06:00

    AMS

    SMTWTFS

  18. KL1351

    KLM

    06:55

    AMS

    1.4h

    08:20

    PRG

    SMTWTFS

  19. BA6518

    British Airways

    14:20

    DSM

    1.5h

    15:49

    ORD

    SMTWTFS
    Search

  20. BA294

    British Airways

    17:00

    ORD

    7.9h

    06:55

    LHR

    SMTWTFS

  21. BA852

    British Airways

    06:45

    LHR

    2.0h

    09:45

    PRG

    SMTWTFS

  22. BA4360

    British Airways

    16:04

    DSM

    1.5h

    17:33

    ORD

    SMTWTFS
    Search

  23. BA296

    British Airways

    21:15

    ORD

    7.8h

    11:00

    LHR

    SMTWTFS

  24. BA856

    British Airways

    15:05

    LHR

    2.1h

    18:10

    PRG

    SMTWTFS

  25. DL2086

    Delta Air Lines

    17:15

    DSM

    2.3h

    20:32

    ATL

    SMTWTFS
    Search

  26. KL622

    KLM

    22:40

    ATL

    8.5h

    13:10

    AMS

    SMTWTFS

  27. KL1357

    KLM

    16:15

    AMS

    1.4h

    17:40

    PRG

    SMTWTFS

  28. UA3433

    United Airlines

    18:45

    DSM

    1.5h

    20:16

    ORD

    SMTWTFS
    Search

  29. UA8854

    United Airlines

    21:40

    ORD

    8.5h

    13:10

    MUC

    SMTWTFS

  30. UA9258

    United Airlines

    15:00

    MUC

    0.8h

    15:50

    PRG

    S--WTFS
Find more flights and airlines

When is the cheapest time to fly from Des Moines to Prague?

Explore the best time to buy affordable tickets to Prague with our price trend chart, which predicts how flight prices will change in the coming weeks from previous data.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Des Moines (DSM) to Prague (PRG) the cheapest?

    Airlines adjust prices for flights from Des Moines to Prague based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Des Moines (DSM) to Prague (PRG) cost?

    According to Trip.com's data, the lowest price is around PHP 80,263.

  • What is the transportation method from the main airport to downtown in Prague?

    • The distance from Vaclav Havel Airport to downtown is about 12 km, by taxi about 30 minutes.

  • How many airports are there in Prague (PRG)?

    There are 1 airport(s) near Prague (PRG): Vaclav Havel Airport.

How to find a cheap flight from Des Moines to Prague

Understanding the common pitfalls when booking your flight tickets can help you save massively when it comes time to fly. We’ve listed our six essential steps to keep in mind when you’re booking flight tickets to help you find the best price.
1
Being flexible with your dates to get the cheapest Des Moines to Prague ticket.
2
Compare cheap Des Moines to Prague flight deals from over hundreds of airlines.
3
Set up a Price Alert
By setting up a Price Alert for your Des Moines to Prague route, you can easily track the price of your airline tickets from without manually checking every day.
4
Don't miss cheap Des Moines to Prague flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights. If registering a free membership, you can receive more deals for your flights.
5
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
6
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com and search for cheap flight tickets from Des Moines to Prague to get exclusive deals for you.

Flight Info | Des Moines to Prague

Off-season for travelJanuary
Peak season for travelDecember
Flight distance7,654.7 km
Popular airlineUnited Airlines

Contact Us

About

Other Services

Payment Methods
Our Partners
Copyright © 2025 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.