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Cheap flight deals from Des Moines to Sao Tome Island Starting at AED 16,047

For as little as AED 16,047, you can take your next adventure to Sao Tome Island without breaking the bank. Choose between one-way and return tickets from Des Moines below.

  • Round-trip
      • DSM11:56
        49h 39m
        2 stops
        TMS17:35
        Fri, Mar 28|Des Moines - Sao Tome Island|American Airlines
        TMS19:40
        31h 37m
        2 stops
        DSM22:17
        Fri, Apr 4|Sao Tome Island - Des Moines|TAP Air Portugal
        AED 16,047AED 39,902
        60% OFF
        60% OFF
        AED 39,902AED 16,047

        Choose American Airlines flights from Des Moines to Sao Tome Island. The one-way connecting flight with American Airlines departs from Des Moines International Airport on Fri, Mar 28-Fri, Apr 4, arriving at São Tomé International Airport. One-way Prices start from AED 16,047 including taxes and charges.

      • DSM05:50
        54h 5m
        2 stops
        TMS17:55
        Fri, Feb 21|Des Moines - Sao Tome Island|American Airlines
        TMS19:25
        33h 57m
        2 stops
        DSM23:22
        Fri, Feb 28|Sao Tome Island - Des Moines|TAP Air Portugal
        AED 16,195AED 39,902
        59% OFF
        59% OFF
        AED 39,902AED 16,195

        Choose American Airlines flights from Des Moines to Sao Tome Island. The one-way connecting flight with American Airlines departs from Des Moines International Airport on Fri, Feb 21-Fri, Feb 28, arriving at São Tomé International Airport. One-way Prices start from AED 16,195 including taxes and charges.

      • DSM06:00
        30h 15m
        2 stops
        TMS17:15
        Fri, Mar 21|Des Moines - Sao Tome Island|American Airlines
        TMS19:25
        32h 35m
        2 stops
        DSM23:00
        Fri, Mar 28|Sao Tome Island - Des Moines|TAP Air Portugal
        AED 19,385AED 39,902
        51% OFF
        51% OFF
        AED 39,902AED 19,385

        Choose American Airlines flights from Des Moines to Sao Tome Island. The one-way connecting flight with American Airlines departs from Des Moines International Airport on Fri, Mar 21-Fri, Mar 28, arriving at São Tomé International Airport. One-way Prices start from AED 19,385 including taxes and charges.

      • DSM05:45
        54h 10m
        2 stops
        TMS17:55
        Fri, Mar 7|Des Moines - Sao Tome Island|American Airlines
        TMS19:25
        32h 35m
        2 stops
        DSM23:00
        Fri, Mar 14|Sao Tome Island - Des Moines|TAP Air Portugal
        AED 19,993
        AED 19,993

        Choose American Airlines flights from Des Moines to Sao Tome Island. The one-way connecting flight with American Airlines departs from Des Moines International Airport on Fri, Mar 7-Fri, Mar 14, arriving at São Tomé International Airport. One-way Prices start from AED 19,993 including taxes and charges.

      • DSM07:00
        28h 55m
        2 stops
        TMS17:55
        Sat, Feb 15|Des Moines - Sao Tome Island|American Airlines
        TMS19:25
        33h 57m
        2 stops
        DSM23:22
        Fri, Feb 21|Sao Tome Island - Des Moines|TAP Air Portugal
        AED 21,672
        AED 21,672

        Choose American Airlines flights from Des Moines to Sao Tome Island. The one-way connecting flight with American Airlines departs from Des Moines International Airport on Sat, Feb 15-Fri, Feb 21, arriving at São Tomé International Airport. One-way Prices start from AED 21,672 including taxes and charges.

      • DSM06:50
        54h 5m
        2 stops
        TMS17:55
        Wed, Mar 12|Des Moines - Sao Tome Island|American Airlines
        TMS19:25
        32h 25m
        2 stops
        DSM22:50
        Wed, Mar 19|Sao Tome Island - Des Moines|TAP Air Portugal
        AED 33,518
        AED 33,518

        Choose American Airlines flights from Des Moines to Sao Tome Island. The one-way connecting flight with American Airlines departs from Des Moines International Airport on Wed, Mar 12-Wed, Mar 19, arriving at São Tomé International Airport. One-way Prices start from AED 33,518 including taxes and charges.

      • DSM01:00 pm
        3h 5m
        Nonstop
        TMS02:00 pm
        Fri, Feb 21|Des Moines - Sao Tome Island|American Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Des Moines to Sao Tome Island flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. AA4367

    American Airlines

    05:50

    DSM

    1.5h

    07:21

    ORD

    SMTWTFS
    Search

  2. TP244

    TAP Air Portugal

    18:00

    ORD

    7.9h

    07:55

    LIS

    --T---S

  3. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.7h

    17:35

    TMS

    --T-T-S

  4. AA5098

    American Airlines

    06:51

    DSM

    2.5h

    10:19

    DCA

    SMTWTFS
    Search

  5. LH8864

    Lufthansa

    22:15

    IAD

    7.3h

    10:30

    LIS

    ---W---

  6. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.7h

    17:35

    TMS

    --T-T-S

  7. AA3522

    American Airlines

    06:59

    DSM

    3.4h

    11:20

    MIA

    SMTWTFS
    Search

  8. TP224

    TAP Air Portugal

    17:00

    MIA

    8.1h

    06:05

    LIS

    S-TWTFS

  9. TP1531

    TAP Air Portugal

    11:40

    LIS

    6.7h

    17:20

    TMS

    -----F-

  10. AA3522

    American Airlines

    06:59

    DSM

    3.4h

    11:20

    MIA

    SMTWTFS
    Search

  11. TP224

    TAP Air Portugal

    17:00

    MIA

    8.1h

    06:05

    LIS

    S-TWTFS

  12. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.7h

    17:35

    TMS

    --T-T-S
Find more flights and airlines

When is the cheapest time to fly from Des Moines to Sao Tome Island?

Explore the best time to buy affordable tickets to Sao Tome Island with our price trend chart, which predicts how flight prices will change in the coming weeks from previous data.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Des Moines (DSM) to Sao Tome Island (TMS) the cheapest?

    Airlines adjust prices for flights from Des Moines to Sao Tome Island based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Des Moines (DSM) to Sao Tome Island (TMS) cost?

    According to Trip.com's data, the lowest price is around AED 13,075.

  • What is the transportation method from the main airport to downtown in Sao Tome Island?

    • The distance from São Tomé International Airport to downtown is about 5 km, by taxi about 20 minutes.

  • How many airports are there in Sao Tome Island (TMS)?

    There are 1 airport(s) near Sao Tome Island (TMS): São Tomé International Airport.

How to find a cheap flight from Des Moines to Sao Tome Island

Understanding the common pitfalls when booking your flight tickets can help you save massively when it comes time to fly. We’ve listed our six essential steps to keep in mind when you’re booking flight tickets to help you find the best price.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | Des Moines to Sao Tome Island

Flight distance10,840.48 km
Popular airlineAmerican Airlines

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