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Cheap flight deals from Des Moines to St. Louis Starting at NZD 148

Discover our range of affordable one-way and round-trip flights from Des Moines to St. Louis and kick-start your next adventure today!

  • One way
  • Round-trip
      • Cheapest nonstop
        DSM17:10
        1h 5m
        Nonstop
        STL18:15
        Tue, Mar 25|Des Moines - St. Louis|Southwest Airlines
        NZD 465NZD 562
        17% OFF
        17% OFF
        NZD 562NZD 465

        Choose Southwest Airlines flights from Des Moines to St. Louis. The one-way direct flight with Southwest Airlines departs from Des Moines International Airport on Tue, Mar 25, arriving at St. Louis Lambert International Airport. One-way Prices start from NZD 465 including taxes and charges.

      • DSM05:30
        1h 20m
        Nonstop
        STL06:50
        Sun, Mar 2|Des Moines - St. Louis|Southwest Airlines
        NZD 472NZD 562
        16% OFF
        16% OFF
        NZD 562NZD 472

        Choose Southwest Airlines flights from Des Moines to St. Louis. The one-way direct flight with Southwest Airlines departs from Des Moines International Airport on Sun, Mar 2, arriving at St. Louis Lambert International Airport. One-way Prices start from NZD 472 including taxes and charges.

      • DSM17:55
        4h 22m
        1 stop
        STL22:17
        Thu, Feb 20|Des Moines - St. Louis|Delta Air Lines
        NZD 148NZD 562
        74% OFF
        74% OFF
        NZD 562NZD 148

        Choose Delta Air Lines flights from Des Moines to St. Louis. The one-way connecting flight with Delta Air Lines departs from Des Moines International Airport on Thu, Feb 20, arriving at St. Louis Lambert International Airport. One-way Prices start from NZD 148 including taxes and charges.

      • DSM06:20
        6h 59m
        1 stop
        STL13:19
        Thu, May 1|Des Moines - St. Louis|Delta Air Lines
        NZD 148
        NZD 148

        Choose Delta Air Lines flights from Des Moines to St. Louis. The one-way connecting flight with Delta Air Lines departs from Des Moines International Airport on Thu, May 1, arriving at St. Louis Lambert International Airport. One-way Prices start from NZD 148 including taxes and charges.

      • DSM18:26
        5h 10m
        1 stop
        STL23:36
        Tue, Mar 4|Des Moines - St. Louis|Delta Air Lines
        NZD 149
        NZD 149

        Choose Delta Air Lines flights from Des Moines to St. Louis. The one-way connecting flight with Delta Air Lines departs from Des Moines International Airport on Tue, Mar 4, arriving at St. Louis Lambert International Airport. One-way Prices start from NZD 149 including taxes and charges.

      • DSM18:26
        5h 10m
        1 stop
        STL23:36
        Wed, Mar 5|Des Moines - St. Louis|Delta Air Lines
        NZD 149
        NZD 149

        Choose Delta Air Lines flights from Des Moines to St. Louis. The one-way connecting flight with Delta Air Lines departs from Des Moines International Airport on Wed, Mar 5, arriving at St. Louis Lambert International Airport. One-way Prices start from NZD 149 including taxes and charges.

      • DSM07:00
        3h 59m
        1 stop
        STL10:59
        Thu, Mar 6|Des Moines - St. Louis|Delta Air Lines
        NZD 149
        NZD 149

        Choose Delta Air Lines flights from Des Moines to St. Louis. The one-way connecting flight with Delta Air Lines departs from Des Moines International Airport on Thu, Mar 6, arriving at St. Louis Lambert International Airport. One-way Prices start from NZD 149 including taxes and charges.

      • DSM17:55
        4h 22m
        1 stop
        STL22:17
        Fri, Mar 7|Des Moines - St. Louis|Delta Air Lines
        NZD 149
        NZD 149

        Choose Delta Air Lines flights from Des Moines to St. Louis. The one-way connecting flight with Delta Air Lines departs from Des Moines International Airport on Fri, Mar 7, arriving at St. Louis Lambert International Airport. One-way Prices start from NZD 149 including taxes and charges.

      • DSM12:25
        4h 12m
        1 stop
        STL16:37
        Sat, Mar 8|Des Moines - St. Louis|Delta Air Lines
        NZD 149
        NZD 149

        Choose Delta Air Lines flights from Des Moines to St. Louis. The one-way connecting flight with Delta Air Lines departs from Des Moines International Airport on Sat, Mar 8, arriving at St. Louis Lambert International Airport. One-way Prices start from NZD 149 including taxes and charges.

      • DSM17:59
        5h 4m
        1 stop
        STL23:03
        Mon, Mar 10|Des Moines - St. Louis|Delta Air Lines
        NZD 149
        NZD 149

        Choose Delta Air Lines flights from Des Moines to St. Louis. The one-way connecting flight with Delta Air Lines departs from Des Moines International Airport on Mon, Mar 10, arriving at St. Louis Lambert International Airport. One-way Prices start from NZD 149 including taxes and charges.

      • DSM01:00 pm
        3h 5m
        Nonstop
        STL02:00 pm
        Fri, Feb 21|Des Moines - St. Louis|Southwest Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Des Moines to St. Louis flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. WN372

    Southwest Airlines

    05:30

    DSM

    1.3h

    Nonstop

    06:50

    STL

    SMTWTFS
    Search

  2. DL5402

    Delta Air Lines

    06:53

    DSM

    1.2h

    08:05

    MSP

    SMTWTFS
    Search

  3. DL1564

    Delta Air Lines

    08:50

    MSP

    1.6h

    10:23

    STL

    SMTWTFS

  4. UA1363

    United Airlines

    08:00

    DSM

    1.5h

    09:28

    ORD

    SMTWTFS
    Search

  5. UA4394

    United Airlines

    10:50

    ORD

    1.5h

    12:20

    STL

    SMTWTFS

  6. UA3404

    United Airlines

    11:29

    DSM

    1.5h

    13:01

    ORD

    -----FS
    Search

  7. UA1693

    United Airlines

    14:20

    ORD

    1.3h

    15:40

    STL

    SMTWTFS

  8. UA1373

    United Airlines

    11:29

    DSM

    1.5h

    12:57

    ORD

    SMTWT-S
    Search

  9. UA1693

    United Airlines

    14:20

    ORD

    1.3h

    15:40

    STL

    SMTWTFS

  10. DL4891

    Delta Air Lines

    12:25

    DSM

    1.8h

    15:14

    DTW

    -----F-
    Search

  11. DL2822

    Delta Air Lines

    16:10

    DTW

    1.7h

    16:50

    STL

    SMTWTFS

  12. AA1991

    American Airlines

    14:07

    DSM

    2.4h

    17:30

    CLT

    SMTWTFS
    Search

  13. AA2686

    American Airlines

    18:25

    CLT

    2.0h

    19:23

    STL

    SMTWTFS

  14. DL4845

    Delta Air Lines

    17:14

    DSM

    1.9h

    20:07

    DTW

    SMTWT--
    Search

  15. DL1541

    Delta Air Lines

    19:55

    DTW

    1.6h

    20:33

    STL

    SMTWTFS

  16. DL4990

    Delta Air Lines

    17:55

    DSM

    1.3h

    19:15

    MSP

    SMTWT--
    Search

  17. DL1609

    Delta Air Lines

    20:00

    MSP

    1.6h

    21:33

    STL

    SMTWTFS

  18. DL2086

    Delta Air Lines

    18:30

    DSM

    2.1h

    21:38

    ATL

    SMTWTFS
    Search

  19. DL1403

    Delta Air Lines

    22:55

    ATL

    1.7h

    23:38

    STL

    SMTWTFS
Find more flights and airlines

When is the cheapest time to fly from Des Moines to St. Louis?

These price trend charts carefully monitor and predict how flight prices from Des Moines to St. Louis will change. Keep a close eye on them to understand when the best time to buy your tickets is.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Des Moines (DSM) to St. Louis (STL) the cheapest?

    Airlines adjust prices for flights from Des Moines to St. Louis based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Des Moines (DSM) to St. Louis (STL) cost?

    According to Trip.com's data, the lowest price is around NZD 627.

  • How long does it take to fly from Des Moines (DSM) to St. Louis (STL)?

    It takes about 1 hour 17 minutes to fly from Des Moines (DSM) to St. Louis (STL).

  • What is the transportation method from the main airport to downtown in St. Louis?

    • The distance from St. Louis Lambert International Airport to downtown is about 20 km, by taxi about 40 minutes.

  • What are the most popular airlines that fly from Des Moines (DSM) to St. Louis (STL)?

    Airlines with flights from Des Moines (DSM) to St. Louis (STL): Southwest Airlines.

  • What's the most popular airline for non-stop flights from Des Moines (DSM) to St. Louis (STL)?

    Hopscotch Air operates 2 non-stop flights from Des Moines (DSM) to St. Louis (STL).

  • How many airports are there in St. Louis (STL)?

    There are 1 airport(s) near St. Louis (STL): St. Louis Lambert International Airport.

How to find a cheap flight from Des Moines to St. Louis

If you don’t know some of the key things to look out for when buying flight tickets, prices can often end up sky high or, worse, sold out! We’ve carefully compiled our six most important steps to help ensure you’re getting the best deals when planning your next journey.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | Des Moines to St. Louis

Cheapest direct flight priceNZD 148
Cheapest return ticket priceNZD 292
Off-season for travelMarch
Peak season for travelNovember
Flight distance438.83 km
Average flight time1 hour 17 minutes
Popular airlineDelta Air Lines

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