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Cheap flight deals from Knoxville to Charleston Starting at €151

Discover our range of affordable one-way and round-trip flights from Knoxville to Charleston and kick-start your next adventure today!

  • One way
  • Round-trip
      • TYS05:45
        4h 22m
        1 stop
        CHS10:07
        Sat, Feb 22|Knoxville - Charleston|Delta Air Lines
        €151€294
        49% OFF
        49% OFF
        €294€151

        Choose Delta Air Lines flights from Knoxville to Charleston. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Sat, Feb 22, arriving at Charleston International Airport. One-way Prices start from €151 including taxes and charges.

      • TYS06:17
        11h 27m
        1 stop
        CHS17:44
        Tue, Apr 8|Knoxville - Charleston|American Airlines
        €158€294
        46% OFF
        46% OFF
        €294€158

        Choose American Airlines flights from Knoxville to Charleston. The one-way connecting flight with American Airlines departs from Mcghee Tyson Airport on Tue, Apr 8, arriving at Charleston International Airport. One-way Prices start from €158 including taxes and charges.

      • TYS11:52
        5h 47m
        1 stop
        CHS17:39
        Fri, Feb 21|Knoxville - Charleston|Delta Air Lines
        €172€294
        42% OFF
        42% OFF
        €294€172

        Choose Delta Air Lines flights from Knoxville to Charleston. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Fri, Feb 21, arriving at Charleston International Airport. One-way Prices start from €172 including taxes and charges.

      • TYS19:58
        3h 59m
        1 stop
        CHS23:57
        Sat, Feb 22|Knoxville - Charleston|American Airlines
        €177
        €177

        Choose American Airlines flights from Knoxville to Charleston. The one-way connecting flight with American Airlines departs from Mcghee Tyson Airport on Sat, Feb 22, arriving at Charleston International Airport. One-way Prices start from €177 including taxes and charges.

      • TYS12:54
        4h 24m
        1 stop
        CHS17:18
        Thu, Apr 3|Knoxville - Charleston|American Airlines
        €243
        €243

        Choose American Airlines flights from Knoxville to Charleston. The one-way connecting flight with American Airlines departs from Mcghee Tyson Airport on Thu, Apr 3, arriving at Charleston International Airport. One-way Prices start from €243 including taxes and charges.

      • TYS18:05
        5h 53m
        1 stop
        CHS23:58
        Fri, Apr 4|Knoxville - Charleston|American Airlines
        €243
        €243

        Choose American Airlines flights from Knoxville to Charleston. The one-way connecting flight with American Airlines departs from Mcghee Tyson Airport on Fri, Apr 4, arriving at Charleston International Airport. One-way Prices start from €243 including taxes and charges.

      • TYS16:22
        3h 6m
        1 stop
        CHS19:28
        Sat, Apr 5|Knoxville - Charleston|American Airlines
        €243
        €243

        Choose American Airlines flights from Knoxville to Charleston. The one-way connecting flight with American Airlines departs from Mcghee Tyson Airport on Sat, Apr 5, arriving at Charleston International Airport. One-way Prices start from €243 including taxes and charges.

      • TYS18:05
        3h 50m
        1 stop
        CHS21:55
        Mon, Apr 7|Knoxville - Charleston|American Airlines
        €243
        €243

        Choose American Airlines flights from Knoxville to Charleston. The one-way connecting flight with American Airlines departs from Mcghee Tyson Airport on Mon, Apr 7, arriving at Charleston International Airport. One-way Prices start from €243 including taxes and charges.

      • TYS14:35
        4h 23m
        1 stop
        CHS18:58
        Fri, Apr 4|Knoxville - Charleston|Delta Air Lines
        €244
        €244

        Choose Delta Air Lines flights from Knoxville to Charleston. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Fri, Apr 4, arriving at Charleston International Airport. One-way Prices start from €244 including taxes and charges.

      • TYS07:00
        5h 48m
        1 stop
        CHS12:48
        Sat, Apr 5|Knoxville - Charleston|Delta Air Lines
        €244
        €244

        Choose Delta Air Lines flights from Knoxville to Charleston. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Sat, Apr 5, arriving at Charleston International Airport. One-way Prices start from €244 including taxes and charges.

      • TYS01:00 pm
        3h 5m
        Nonstop
        CHS02:00 pm
        Thu, Feb 20|Knoxville - Charleston|Delta Air Lines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Knoxville to Charleston flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. DL3015

    Delta Air Lines

    05:30

    TYS

    1.0h

    06:29

    ATL

    SMTWTFS
    Search

  2. DL3107

    Delta Air Lines

    10:10

    ATL

    1.2h

    11:23

    CHS

    SMTWTFS

  3. DL3015

    Delta Air Lines

    05:30

    TYS

    1.0h

    06:29

    ATL

    SMTWTFS
    Search

  4. DL3091

    Delta Air Lines

    08:15

    ATL

    1.2h

    09:26

    CHS

    SMTWT--

  5. AA5087

    American Airlines

    06:58

    TYS

    1.4h

    08:20

    CLT

    SMTWTFS
    Search

  6. AA1426

    American Airlines

    09:00

    CLT

    1.1h

    10:07

    CHS

    SMTWTFS

  7. DL857

    Delta Air Lines

    12:08

    TYS

    1.1h

    13:13

    ATL

    SMTWTFS
    Search

  8. DL3189

    Delta Air Lines

    14:30

    ATL

    1.1h

    15:37

    CHS

    SMTWTFS

  9. DL5475

    Delta Air Lines

    14:30

    TYS

    1.1h

    15:35

    ATL

    SMTWTF-
    Search

  10. DL3179

    Delta Air Lines

    17:44

    ATL

    1.2h

    18:54

    CHS

    SMTWTFS

  11. AA5176

    American Airlines

    14:43

    TYS

    1.4h

    16:04

    CLT

    SMTWTFS
    Search

  12. AA1586

    American Airlines

    18:54

    CLT

    1.1h

    19:58

    CHS

    SMTWTFS

  13. DL4886

    Delta Air Lines

    19:17

    TYS

    1.3h

    20:35

    ATL

    SMTWT--
    Search

  14. DL2850

    Delta Air Lines

    22:30

    ATL

    1.2h

    23:40

    CHS

    SMTWTFS

  15. DL4886

    Delta Air Lines

    19:17

    TYS

    1.3h

    20:35

    ATL

    SMTWT--
    Search

  16. DL1663

    Delta Air Lines

    20:55

    ATL

    1.1h

    22:04

    CHS

    S--WT-S

  17. DL3042

    Delta Air Lines

    19:25

    TYS

    1.1h

    20:31

    ATL

    -MT---S
    Search

  18. DL2850

    Delta Air Lines

    22:30

    ATL

    1.2h

    23:40

    CHS

    SMTWTFS

  19. AA5173

    American Airlines

    20:24

    TYS

    1.4h

    21:50

    CLT

    SMTWTFS
    Search

  20. AA2773

    American Airlines

    23:00

    CLT

    1.1h

    00:07

    CHS

    SMTWTFS
Find more flights and airlines

When is the cheapest time to fly from Knoxville to Charleston?

Price trend charts are a great way of tracking how much your flights cost in the lead up to departure and can help you choose when to book your tickets. See how prices to Charleston from Knoxville have changed and are set to move below.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Knoxville (TYS) to Charleston (CHS) the cheapest?

    Airlines adjust prices for flights from Knoxville to Charleston based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Knoxville (TYS) to Charleston (CHS) cost?

    According to Trip.com's data, the lowest price is around €461.

  • What is the transportation method from the main airport to downtown in Charleston?

    • The distance from Charleston International Airport to downtown is about 16 km, by taxi about 30 minutes.

  • How many airports are there in Charleston (CHS)?

    There are 1 airport(s) near Charleston (CHS): Charleston International Airport.

How to find a cheap flight from Knoxville to Charleston

If you leave it until the last minute and forget to check some of the key information when booking tickets, prices can often end up skyrocketing. Below, you can find our top tips for getting the best value flights – from changing dates to chasing deals, there are plenty ways to keep your next trip affordable.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | Knoxville to Charleston

Cheapest direct flight price€150
Off-season for travelFebruary
Peak season for travelNovember
Flight distance486.33 km
Popular airlineAmerican Airlines

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