App
Customer Support
EUR
Find Bookings
Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Cheap flight deals from Knoxville to Charleston Starting at €280

Whether you’re going for a one-way or round-trip to Charleston, we’ve got you covered! Check out these different flight options from Knoxville below.

  • Round-trip
      • TYS05:45
        5h 2m
        1 stop
        CRW10:47
        Wed, Feb 26|Knoxville - Charleston|Delta Air Lines
        CRW11:37
        4h 57m
        1 stop
        TYS16:34
        Tue, Mar 4|Charleston - Knoxville|Delta Air Lines
        €280€555
        50% OFF
        50% OFF
        €555€280

        Choose Delta Air Lines flights from Knoxville to Charleston. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Wed, Feb 26-Tue, Mar 4, arriving at Yeager Airport. One-way Prices start from €280 including taxes and charges.

      • TYS12:08
        5h 2m
        1 stop
        CRW17:10
        Wed, Feb 19|Knoxville - Charleston|Delta Air Lines
        CRW06:00
        3h 16m
        1 stop
        TYS09:16
        Tue, Feb 25|Charleston - Knoxville|Delta Air Lines
        €283€555
        49% OFF
        49% OFF
        €555€283

        Choose Delta Air Lines flights from Knoxville to Charleston. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Wed, Feb 19-Tue, Feb 25, arriving at Yeager Airport. One-way Prices start from €283 including taxes and charges.

      • TYS05:45
        5h 2m
        1 stop
        CRW10:47
        Tue, Feb 25|Knoxville - Charleston|Delta Air Lines
        CRW17:50
        5h 57m
        1 stop
        TYS23:47
        Mon, Mar 3|Charleston - Knoxville|Delta Air Lines
        €325€555
        41% OFF
        41% OFF
        €555€325

        Choose Delta Air Lines flights from Knoxville to Charleston. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Tue, Feb 25-Mon, Mar 3, arriving at Yeager Airport. One-way Prices start from €325 including taxes and charges.

      • TYS05:45
        5h 2m
        1 stop
        CRW10:47
        Thu, Feb 20|Knoxville - Charleston|Delta Air Lines
        CRW15:01
        5h 3m
        1 stop
        TYS20:04
        Wed, Feb 26|Charleston - Knoxville|Delta Air Lines
        €328
        €328

        Choose Delta Air Lines flights from Knoxville to Charleston. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Thu, Feb 20-Wed, Feb 26, arriving at Yeager Airport. One-way Prices start from €328 including taxes and charges.

      • TYS05:45
        5h 2m
        1 stop
        CRW10:47
        Tue, Feb 18|Knoxville - Charleston|Delta Air Lines
        CRW17:50
        3h 35m
        1 stop
        TYS21:25
        Mon, Feb 24|Charleston - Knoxville|Delta Air Lines
        €329
        €329

        Choose Delta Air Lines flights from Knoxville to Charleston. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Tue, Feb 18-Mon, Feb 24, arriving at Yeager Airport. One-way Prices start from €329 including taxes and charges.

      • TYS05:45
        5h 2m
        1 stop
        CRW10:47
        Sat, Feb 22|Knoxville - Charleston|Delta Air Lines
        CRW17:50
        5h 57m
        1 stop
        TYS23:47
        Fri, Feb 28|Charleston - Knoxville|Delta Air Lines
        €371
        €371

        Choose Delta Air Lines flights from Knoxville to Charleston. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Sat, Feb 22-Fri, Feb 28, arriving at Yeager Airport. One-way Prices start from €371 including taxes and charges.

      • TYS05:45
        5h 2m
        1 stop
        CRW10:47
        Fri, Feb 28|Knoxville - Charleston|Delta Air Lines
        CRW06:00
        3h 16m
        1 stop
        TYS09:16
        Thu, Mar 6|Charleston - Knoxville|Delta Air Lines
        €374
        €374

        Choose Delta Air Lines flights from Knoxville to Charleston. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Fri, Feb 28-Thu, Mar 6, arriving at Yeager Airport. One-way Prices start from €374 including taxes and charges.

      • TYS05:45
        4h 50m
        1 stop
        CRW10:35
        Fri, Mar 14|Knoxville - Charleston|Delta Air Lines
        CRW06:00
        5h 14m
        1 stop
        TYS11:14
        Tue, Mar 18|Charleston - Knoxville|Delta Air Lines
        €386
        €386

        Choose Delta Air Lines flights from Knoxville to Charleston. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Fri, Mar 14-Tue, Mar 18, arriving at Yeager Airport. One-way Prices start from €386 including taxes and charges.

      • TYS19:17
        3h 24m
        1 stop
        CRW22:41
        Fri, Feb 21|Knoxville - Charleston|Delta Air Lines
        CRW06:00
        3h 16m
        1 stop
        TYS09:16
        Thu, Feb 27|Charleston - Knoxville|Delta Air Lines
        €402
        €402

        Choose Delta Air Lines flights from Knoxville to Charleston. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Fri, Feb 21-Thu, Feb 27, arriving at Yeager Airport. One-way Prices start from €402 including taxes and charges.

      • TYS07:00
        9h 44m
        1 stop
        CRW16:44
        Tue, Feb 25|Knoxville - Charleston|United Airlines
        CRW17:30
        19h 45m
        1 stop
        TYS13:15
        Mon, Mar 3|Charleston - Knoxville|United Airlines
        €457
        €457

        Choose United Airlines flights from Knoxville to Charleston. The one-way connecting flight with United Airlines departs from Mcghee Tyson Airport on Tue, Feb 25-Mon, Mar 3, arriving at Yeager Airport. One-way Prices start from €457 including taxes and charges.

      • TYS01:00 pm
        3h 5m
        Nonstop
        CRW02:00 pm
        Fri, Feb 21|Knoxville - Charleston|Delta Air Lines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Knoxville to Charleston flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. DL3015

    Delta Air Lines

    05:30

    TYS

    1.0h

    06:29

    ATL

    SMTWTFS
    Search

  2. DL4850

    Delta Air Lines

    09:23

    ATL

    1.4h

    10:47

    CRW

    SMTWTFS

  3. UA2046

    United Airlines

    07:00

    TYS

    2.0h

    08:03

    ORD

    SMTWTFS
    Search

  4. UA5790

    United Airlines

    18:20

    ORD

    1.8h

    21:05

    CRW

    SMTWTFS

  5. UA2046

    United Airlines

    07:00

    TYS

    2.0h

    08:03

    ORD

    SMTWTFS
    Search

  6. UA5439

    United Airlines

    14:08

    ORD

    1.8h

    16:58

    CRW

    SMTWTFS

  7. DL857

    Delta Air Lines

    12:08

    TYS

    1.1h

    13:13

    ATL

    SMTWTFS
    Search

  8. DL3811

    Delta Air Lines

    15:46

    ATL

    1.4h

    17:10

    CRW

    SMTWT-S

  9. UA3616

    United Airlines

    17:35

    TYS

    2.0h

    18:37

    ORD

    -----F-
    Search

  10. UA5790

    United Airlines

    18:20

    ORD

    1.8h

    21:05

    CRW

    SMTWTFS

  11. UA5305

    United Airlines

    17:47

    TYS

    2.0h

    18:50

    ORD

    SMTWT--
    Search

  12. UA5790

    United Airlines

    18:20

    ORD

    1.8h

    21:05

    CRW

    SMTWTFS

  13. DL4886

    Delta Air Lines

    19:17

    TYS

    1.3h

    20:35

    ATL

    SMTWT--
    Search

  14. DL3810

    Delta Air Lines

    21:10

    ATL

    1.4h

    22:34

    CRW

    SMTWTFS
Find more flights and airlines

When is the cheapest time to fly from Knoxville to Charleston?

These price trend charts carefully monitor and predict how flight prices from Knoxville to Charleston will change. Keep a close eye on them to understand when the best time to buy your tickets is.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Knoxville (TYS) to Charleston (CRW) the cheapest?

    Airlines adjust prices for flights from Knoxville to Charleston based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Knoxville (TYS) to Charleston (CRW) cost?

    According to Trip.com's data, the lowest price is around €574.

  • What is the transportation method from the main airport to downtown in Charleston?

    • The distance from Yeager Airport to downtown is about 3 km, by taxi about 20 minutes.

  • How many airports are there in Charleston (CRW)?

    There are 1 airport(s) near Charleston (CRW): Yeager Airport.

How to find a cheap flight from Knoxville to Charleston

Understanding the common pitfalls when booking your flight tickets can help you save massively when it comes time to fly. We’ve listed our six essential steps to keep in mind when you’re booking flight tickets to help you find the best price.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | Knoxville to Charleston

Off-season for travelFebruary
Peak season for travelDecember
Flight distance355.65 km
Popular airlineDelta Air Lines

Contact Us

About

Other Services

Payment Methods
Our Partners
Copyright © 2025 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.