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Flights from Knoxville to Panama City
Cheap flight deals from Knoxville to Panama City
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
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Round-trip
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One way
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TYS 05:453h 31m1 stopsECP 08:16Knoxville - Panama City | Thu, May 22 | Delta Air LinesECP 09:125h 5m1 stopsTYS 15:17Panama City - Knoxville | Sun, May 25 | Delta Air LinesAED 1,193 AED 1,94639% OFF39% OFFAED 1,946 AED 1,193
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TYS 05:453h 41m1 stopsECP 08:26Knoxville - Panama City | Sat, May 24 | Delta Air LinesECP 07:153h 8m1 stopsTYS 11:23Panama City - Knoxville | Tue, May 27 | Delta Air LinesAED 1,272 AED 1,94635% OFF35% OFFAED 1,946 AED 1,272
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TYS 05:303h 56m1 stopsECP 08:26Knoxville - Panama City | Sat, Apr 19 | Delta Air LinesECP 06:004h 9m1 stopsTYS 11:09Panama City - Knoxville | Wed, Apr 23 | Delta Air LinesAED 1,287 AED 1,94634% OFF34% OFFAED 1,946 AED 1,287
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TYS 19:244h 39m1 stopsECP 23:03Knoxville - Panama City | Fri, May 2 | Delta Air LinesECP 18:384h 10m1 stopsTYS 23:48Panama City - Knoxville | Mon, May 5 | Delta Air LinesAED 1,31333% OFFAED 1,946 AED 1,313
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TYS 05:455h 4m1 stopsECP 09:49Knoxville - Panama City | Fri, May 9 | Delta Air LinesECP 18:593h 52m1 stopsTYS 23:51Panama City - Knoxville | Sun, May 11 | Delta Air LinesAED 1,31333% OFFAED 1,946 AED 1,313
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TYS 05:453h 41m1 stopsECP 08:26Knoxville - Panama City | Fri, Jun 6 | Delta Air LinesECP 09:234h 45m1 stopsTYS 15:08Panama City - Knoxville | Thu, Jun 12 | Delta Air LinesAED 1,33631% OFFAED 1,946 AED 1,336
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TYS 05:303h 56m1 stopsECP 08:26Knoxville - Panama City | Fri, Apr 25 | Delta Air LinesECP 18:384h 10m1 stopsTYS 23:48Panama City - Knoxville | Thu, May 1 | Delta Air LinesAED 1,44726% OFFAED 1,946 AED 1,447
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TYS 05:305h 43m1 stopsECP 10:13Knoxville - Panama City | Mon, May 12 | Delta Air LinesECP 09:234h 43m1 stopsTYS 15:06Panama City - Knoxville | Mon, May 19 | Delta Air LinesAED 1,46125% OFFAED 1,946 AED 1,461
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TYS 05:453h 46m1 stopsECP 08:31Knoxville - Panama City | Thu, Apr 10 | Delta Air LinesECP 18:503h 52m1 stopsTYS 23:42Panama City - Knoxville | Sun, Apr 13 | Delta Air LinesAED 1,54820% OFFAED 1,946 AED 1,548
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TYS 14:336h 7m1 stopsECP 19:40Knoxville - Panama City | Fri, Apr 18 | Delta Air LinesECP 06:004h 9m1 stopsTYS 11:09Panama City - Knoxville | Tue, Apr 22 | Delta Air LinesAED 1,55720% OFFAED 1,946 AED 1,557
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TYS 13:0017h 25m1 stopsECP Invalid DateKnoxville - Panama City | Sat, Apr 12 | Normal AirlineECP 15:006hNonstopTYS 16:00Panama City - Knoxville | Mon, Apr 14 | Normal AirlineFind More FlightsFind More Flights
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TYS 19:244h 39m1 stopsECP 23:03Knoxville - Panama City | Fri, May 2 | Delta Air LinesAED 842 AED 1,57847% OFF47% OFFAED 1,578 AED 842
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TYS 05:303h 56m1 stopsECP 08:26Knoxville - Panama City | Sat, Apr 26 | Delta Air LinesAED 906 AED 1,57843% OFF43% OFFAED 1,578 AED 906
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TYS 05:303h 56m1 stopsECP 08:26Knoxville - Panama City | Sun, Apr 27 | Delta Air LinesAED 907 AED 1,57843% OFF43% OFFAED 1,578 AED 907
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TYS 17:003h 40m1 stopsECP 19:40Knoxville - Panama City | Mon, Apr 28 | Delta Air LinesAED 90743% OFFAED 1,578 AED 907
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TYS 05:305h 44m1 stopsECP 10:14Knoxville - Panama City | Wed, Apr 30 | Delta Air LinesAED 90742% OFFAED 1,578 AED 907
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TYS 05:453h 46m1 stopsECP 08:31Knoxville - Panama City | Thu, Apr 10 | Delta Air LinesAED 95040% OFFAED 1,578 AED 950
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TYS 07:007h 25m1 stopsECP 13:25Knoxville - Panama City | Tue, Apr 22 | United AirlinesAED 98637% OFFAED 1,578 AED 986
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TYS 19:244h 39m1 stopsECP 23:03Knoxville - Panama City | Thu, May 1 | Delta Air LinesAED 1,10630% OFFAED 1,578 AED 1,106
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TYS 05:159h 10m1 stopsECP 13:25Knoxville - Panama City | Tue, Apr 22 | American AirlinesAED 1,11428% OFFAED 1,578 AED 1,114
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TYS 05:159h 10m1 stopsECP 13:25Knoxville - Panama City | Wed, Apr 23 | American AirlinesAED 1,26220% OFFAED 1,578 AED 1,262
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TYS 13:0017h 25m1 stopsECP Invalid DateKnoxville - Panama City | Sat, Apr 12 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
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Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Frequently Asked Questions
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When are flight tickets from Knoxville (TYS) to Panama City (ECP) the cheapest?
Airlines adjust prices for flights from Knoxville to Panama City based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much do flights from Knoxville (TYS) to Panama City (ECP) cost?
According to Trip.com's data, the lowest price is around AED 2,385. -
How many airports are there in Panama City (ECP)?
There are 1 airport(s) near Panama City (ECP): Northwest Florida Beaches International Airport.
How to find a cheap flight from Knoxville to Panama City
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Knoxville to Panama City. Book your flights at the right time and save more.
Being flexible with your dates to get the cheapest Knoxville to Panama City ticket.
Tap "Date" on flight search bar to scan through the calender for Knoxville to Panama City airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Fri, May 2 at AED 842 for one-way flights.
Compare cheap Knoxville to Panama City flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from Knoxville to Panama City. The cheapest airline operating is Delta Air Lines.
Set up a Price Alert
By setting up a Price Alert for your Knoxville to Panama City route, you can easily track the price of your airline tickets from without manually checking every day.
Don't miss cheap Knoxville to Panama City flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights. If registering a free membership, you can receive more deals for your flights.
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com and search for cheap flight tickets from Knoxville to Panama City to get exclusive deals for you.
Flight Info | Knoxville to Panama City
Cheapest one-way flight price | AED 842 |
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Off-season for travel | May |
Peak season for travel | January |
Flight distance | 645.84 km |
Popular airline | Delta Air Lines |
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