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Flights from Knoxville to Panama City
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Cheap flight deals from Knoxville to Panama City Starting at NZD 453

For as little as NZD 453, you can take your next adventure to Panama City without breaking the bank. Choose between one-way and return tickets from Knoxville below.

  • One way
  • Round-trip
      • TYS05:45
        3h 46m
        1 stop
        ECP08:31
        Thu, Apr 3|Knoxville - Panama City|Delta Air Lines
        NZD 453NZD 1,104
        59% OFF
        59% OFF
        NZD 1,104NZD 453

        Choose Delta Air Lines flights from Knoxville to Panama City. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Thu, Apr 3, arriving at Northwest Florida Beaches International Airport. One-way Prices start from NZD 453 including taxes and charges.

      • TYS05:45
        3h 46m
        1 stop
        ECP08:31
        Thu, Apr 10|Knoxville - Panama City|Delta Air Lines
        NZD 456NZD 1,104
        59% OFF
        59% OFF
        NZD 1,104NZD 456

        Choose Delta Air Lines flights from Knoxville to Panama City. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Thu, Apr 10, arriving at Northwest Florida Beaches International Airport. One-way Prices start from NZD 456 including taxes and charges.

      • TYS05:45
        3h 40m
        1 stop
        ECP08:25
        Thu, Feb 27|Knoxville - Panama City|Delta Air Lines
        NZD 462NZD 1,104
        57% OFF
        57% OFF
        NZD 1,104NZD 462

        Choose Delta Air Lines flights from Knoxville to Panama City. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Thu, Feb 27, arriving at Northwest Florida Beaches International Airport. One-way Prices start from NZD 462 including taxes and charges.

      • TYS11:05
        5h 48m
        1 stop
        ECP15:53
        Thu, Apr 3|Knoxville - Panama City|American Airlines
        NZD 487
        NZD 487

        Choose American Airlines flights from Knoxville to Panama City. The one-way connecting flight with American Airlines departs from Mcghee Tyson Airport on Thu, Apr 3, arriving at Northwest Florida Beaches International Airport. One-way Prices start from NZD 487 including taxes and charges.

      • TYS17:25
        21h
        1 stop
        ECP13:25
        Wed, Apr 9|Knoxville - Panama City|United Airlines
        NZD 716
        NZD 716

        Choose United Airlines flights from Knoxville to Panama City. The one-way connecting flight with United Airlines departs from Mcghee Tyson Airport on Wed, Apr 9, arriving at Northwest Florida Beaches International Airport. One-way Prices start from NZD 716 including taxes and charges.

      • TYS07:00
        10h 17m
        1 stop
        ECP16:17
        Thu, Apr 3|Knoxville - Panama City|United Airlines
        NZD 793
        NZD 793

        Choose United Airlines flights from Knoxville to Panama City. The one-way connecting flight with United Airlines departs from Mcghee Tyson Airport on Thu, Apr 3, arriving at Northwest Florida Beaches International Airport. One-way Prices start from NZD 793 including taxes and charges.

      • TYS16:59
        24h 18m
        1 stop
        ECP16:17
        Thu, Apr 10|Knoxville - Panama City|United Airlines
        NZD 920
        NZD 920

        Choose United Airlines flights from Knoxville to Panama City. The one-way connecting flight with United Airlines departs from Mcghee Tyson Airport on Thu, Apr 10, arriving at Northwest Florida Beaches International Airport. One-way Prices start from NZD 920 including taxes and charges.

      • TYS07:00
        7h 17m
        1 stop
        ECP13:17
        Fri, Mar 14|Knoxville - Panama City|United Airlines
        NZD 972
        NZD 972

        Choose United Airlines flights from Knoxville to Panama City. The one-way connecting flight with United Airlines departs from Mcghee Tyson Airport on Fri, Mar 14, arriving at Northwest Florida Beaches International Airport. One-way Prices start from NZD 972 including taxes and charges.

      • TYS01:00 pm
        3h 5m
        Nonstop
        ECP02:00 pm
        Sun, Feb 23|Knoxville - Panama City|Delta Air Lines
        Find More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Knoxville to Panama City flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. DL3015

    Delta Air Lines

    05:30

    TYS

    1.1h

    06:36

    ATL

    SMTWTFS
    Search

  2. DL3045

    Delta Air Lines

    10:05

    ATL

    1.1h

    10:13

    ECP

    SMTWTFS

  3. DL3015

    Delta Air Lines

    05:30

    TYS

    1.1h

    06:36

    ATL

    SMTWTFS
    Search

  4. DL3048

    Delta Air Lines

    08:10

    ATL

    1.2h

    08:20

    ECP

    SMTWTFS

  5. DL5116

    Delta Air Lines

    06:45

    TYS

    2.1h

    08:52

    LGA

    SMTWTFS
    Search

  6. DL989

    Delta Air Lines

    10:00

    LGA

    2.8h

    12:46

    ATL

    SMTWT-S

  7. DL3094

    Delta Air Lines

    15:10

    ATL

    1.1h

    15:17

    ECP

    SMTWT--

  8. AA5087

    American Airlines

    06:58

    TYS

    1.4h

    08:20

    CLT

    SMTWTFS
    Search

  9. AA5327

    American Airlines

    09:10

    CLT

    1.9h

    10:04

    ECP

    SMTWTFS

  10. UA2046

    United Airlines

    07:00

    TYS

    2.0h

    08:03

    ORD

    SMTWTFS
    Search

  11. UA2417

    United Airlines

    12:45

    ORD

    3.0h

    15:45

    IAH

    SMTWTFS

  12. UA6204

    United Airlines

    18:25

    IAH

    1.9h

    20:19

    ECP

    SMTWTFS

  13. AA5417

    American Airlines

    09:09

    TYS

    1.3h

    10:24

    CLT

    SMTWTFS
    Search

  14. AA1734

    American Airlines

    08:59

    CLT

    1.5h

    09:28

    ECP

    SMTWTFS

  15. DL1418

    Delta Air Lines

    10:03

    TYS

    1.1h

    11:08

    ATL

    SMTWT--
    Search

  16. DL3045

    Delta Air Lines

    10:05

    ATL

    1.1h

    10:13

    ECP

    SMTWTFS

  17. DL5472

    Delta Air Lines

    17:15

    TYS

    1.1h

    18:24

    ATL

    -----F-
    Search

  18. DL2494

    Delta Air Lines

    20:10

    ATL

    1.1h

    20:16

    ECP

    SMTWTFS

  19. DL4886

    Delta Air Lines

    19:17

    TYS

    1.3h

    20:35

    ATL

    SMTWT--
    Search

  20. DL3131

    Delta Air Lines

    22:35

    ATL

    1.1h

    22:42

    ECP

    SMTWTFS

  21. DL3042

    Delta Air Lines

    19:25

    TYS

    1.2h

    20:39

    ATL

    -MT---S
    Search

  22. DL3131

    Delta Air Lines

    22:35

    ATL

    1.1h

    22:42

    ECP

    SMTWTFS
Find more flights and airlines

When is the cheapest time to fly from Knoxville to Panama City?

Explore the best time to buy affordable tickets to Panama City with our price trend chart, which predicts how flight prices will change in the coming weeks from previous data.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Knoxville (TYS) to Panama City (ECP) the cheapest?

    Airlines adjust prices for flights from Knoxville to Panama City based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Knoxville (TYS) to Panama City (ECP) cost?

    According to Trip.com's data, the lowest price is around NZD 1,145.

  • How many airports are there in Panama City (ECP)?

    There are 1 airport(s) near Panama City (ECP): Northwest Florida Beaches International Airport.

How to find a cheap flight from Knoxville to Panama City

Understanding the common pitfalls when booking your flight tickets can help you save massively when it comes time to fly. We’ve listed our six essential steps to keep in mind when you’re booking flight tickets to help you find the best price.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | Knoxville to Panama City

Cheapest direct flight priceNZD 453
Off-season for travelApril
Peak season for travelNovember
Flight distance645.84 km
Popular airlineDelta Air Lines

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