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Cheap flight deals from Knoxville to San Diego Starting at MYR 464

Discover our range of affordable one-way and round-trip flights from Knoxville to San Diego and kick-start your next adventure today!

  • One way
  • Round-trip
      • TYS16:23
        10h 57m
        1 stop
        SAN00:20
        Thu, Mar 27|Knoxville - San Diego|Frontier Airlines
        MYR 464MYR 1,590
        71% OFF
        71% OFF
        MYR 1,590MYR 464

        Choose Frontier Airlines flights from Knoxville to San Diego. The one-way connecting flight with Frontier Airlines departs from Mcghee Tyson Airport on Thu, Mar 27, arriving at San Diego International Airport. One-way Prices start from MYR 464 including taxes and charges.

      • TYS14:30
        7h 11m
        1 stop
        SAN18:41
        Tue, Apr 22|Knoxville - San Diego|Delta Air Lines
        MYR 605MYR 1,590
        62% OFF
        62% OFF
        MYR 1,590MYR 605

        Choose Delta Air Lines flights from Knoxville to San Diego. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Tue, Apr 22, arriving at San Diego International Airport. One-way Prices start from MYR 605 including taxes and charges.

      • TYS05:40
        8h 56m
        1 stop
        SAN11:36
        Tue, Mar 18|Knoxville - San Diego|United Airlines
        MYR 693MYR 1,590
        56% OFF
        56% OFF
        MYR 1,590MYR 693

        Choose United Airlines flights from Knoxville to San Diego. The one-way connecting flight with United Airlines departs from Mcghee Tyson Airport on Tue, Mar 18, arriving at San Diego International Airport. One-way Prices start from MYR 693 including taxes and charges.

      • TYS16:16
        7h 49m
        1 stop
        SAN21:05
        Sat, Feb 15|Knoxville - San Diego|American Airlines
        MYR 696
        MYR 696

        Choose American Airlines flights from Knoxville to San Diego. The one-way connecting flight with American Airlines departs from Mcghee Tyson Airport on Sat, Feb 15, arriving at San Diego International Airport. One-way Prices start from MYR 696 including taxes and charges.

      • TYS14:40
        9h 19m
        1 stop
        SAN20:59
        Sat, Feb 15|Knoxville - San Diego|United Airlines
        MYR 697
        MYR 697

        Choose United Airlines flights from Knoxville to San Diego. The one-way connecting flight with United Airlines departs from Mcghee Tyson Airport on Sat, Feb 15, arriving at San Diego International Airport. One-way Prices start from MYR 697 including taxes and charges.

      • TYS07:05
        9h 58m
        1 stop
        SAN14:03
        Wed, Mar 26|Knoxville - San Diego|United Airlines
        MYR 705
        MYR 705

        Choose United Airlines flights from Knoxville to San Diego. The one-way connecting flight with United Airlines departs from Mcghee Tyson Airport on Wed, Mar 26, arriving at San Diego International Airport. One-way Prices start from MYR 705 including taxes and charges.

      • TYS18:36
        18h 6m
        1 stop
        SAN09:42
        Sat, Feb 22|Knoxville - San Diego|American Airlines
        MYR 1,099
        MYR 1,099

        Choose American Airlines flights from Knoxville to San Diego. The one-way connecting flight with American Airlines departs from Mcghee Tyson Airport on Sat, Feb 22, arriving at San Diego International Airport. One-way Prices start from MYR 1,099 including taxes and charges.

      • TYS05:45
        7h 53m
        1 stop
        SAN10:38
        Sat, Feb 22|Knoxville - San Diego|Delta Air Lines
        MYR 1,168
        MYR 1,168

        Choose Delta Air Lines flights from Knoxville to San Diego. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Sat, Feb 22, arriving at San Diego International Airport. One-way Prices start from MYR 1,168 including taxes and charges.

      • TYS14:35
        9h 13m
        1 stop
        SAN20:48
        Mon, Mar 24|Knoxville - San Diego|Delta Air Lines
        MYR 1,209
        MYR 1,209

        Choose Delta Air Lines flights from Knoxville to San Diego. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Mon, Mar 24, arriving at San Diego International Airport. One-way Prices start from MYR 1,209 including taxes and charges.

      • TYS05:45
        7h 53m
        1 stop
        SAN10:38
        Tue, Mar 4|Knoxville - San Diego|Delta Air Lines
        MYR 1,212
        MYR 1,212

        Choose Delta Air Lines flights from Knoxville to San Diego. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Tue, Mar 4, arriving at San Diego International Airport. One-way Prices start from MYR 1,212 including taxes and charges.

      • TYS01:00 pm
        3h 5m
        Nonstop
        SAN02:00 pm
        Sat, Feb 22|Knoxville - San Diego|Frontier Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Knoxville to San Diego flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. AA994

    American Airlines

    05:22

    TYS

    2.5h

    06:54

    DFW

    SMTWTFS
    Search

  2. AA2366

    American Airlines

    08:52

    DFW

    3.4h

    10:15

    SAN

    SMTWTFS

  3. DL3015

    Delta Air Lines

    05:30

    TYS

    1.0h

    06:29

    ATL

    SMTWTFS
    Search

  4. DL725

    Delta Air Lines

    08:20

    ATL

    4.8h

    10:05

    SAN

    SMTWTFS

  5. DL5523

    Delta Air Lines

    06:45

    TYS

    2.5h

    08:15

    MSP

    SMTWTFS
    Search

  6. DL2121

    Delta Air Lines

    08:50

    MSP

    4.2h

    10:59

    SAN

    SMTWTFS

  7. UA2046

    United Airlines

    07:00

    TYS

    2.0h

    08:03

    ORD

    SMTWTFS
    Search

  8. UA660

    United Airlines

    09:06

    ORD

    4.6h

    11:43

    SAN

    SMTWTFS

  9. AA5417

    American Airlines

    09:09

    TYS

    1.3h

    10:24

    CLT

    SMTWTFS
    Search

  10. AA466

    American Airlines

    11:23

    CLT

    5.2h

    13:36

    SAN

    SMTWTFS

  11. DL4921

    Delta Air Lines

    17:55

    TYS

    1.8h

    19:41

    DTW

    SMTWT-S
    Search

  12. DL369

    Delta Air Lines

    16:30

    DTW

    5.0h

    18:27

    SAN

    SMTWTFS

  13. DL4921

    Delta Air Lines

    17:55

    TYS

    1.8h

    19:41

    DTW

    SMTWT-S
    Search

  14. DL700

    Delta Air Lines

    20:30

    DTW

    5.0h

    22:30

    SAN

    S-TWT-S

  15. DL4886

    Delta Air Lines

    19:17

    TYS

    1.3h

    20:35

    ATL

    SMTWT--
    Search

  16. DL403

    Delta Air Lines

    21:30

    ATL

    4.8h

    23:20

    SAN

    --T----

  17. DL4886

    Delta Air Lines

    19:17

    TYS

    1.3h

    20:35

    ATL

    SMTWT--
    Search

  18. DL896

    Delta Air Lines

    21:15

    ATL

    4.8h

    23:03

    SAN

    SMTWTFS

  19. DL3042

    Delta Air Lines

    19:25

    TYS

    1.1h

    20:31

    ATL

    -MT---S
    Search

  20. DL896

    Delta Air Lines

    21:15

    ATL

    4.8h

    23:03

    SAN

    SMTWTFS
Find more flights and airlines

When is the cheapest time to fly from Knoxville to San Diego?

Price trend charts are a great way of tracking how much your flights cost in the lead up to departure and can help you choose when to book your tickets. See how prices to San Diego from Knoxville have changed and are set to move below.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Knoxville (TYS) to San Diego (SAN) the cheapest?

    Airlines adjust prices for flights from Knoxville to San Diego based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Knoxville (TYS) to San Diego (SAN) cost?

    According to Trip.com's data, the lowest price is around MYR 1,758.

  • What is the transportation method from the main airport to downtown in San Diego?

    • The distance from San Diego International Airport to downtown is about 3 km, by taxi about 20 minutes.

  • How many airports are there in San Diego (SAN)?

    There are 2 airport(s) near San Diego (SAN): McClellan-Palomar Airport and San Diego International Airport.

How to find a cheap flight from Knoxville to San Diego

Understanding the common pitfalls when booking your flight tickets can help you save massively when it comes time to fly. We’ve listed our six essential steps to keep in mind when you’re booking flight tickets to help you find the best price.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | Knoxville to San Diego

Cheapest direct flight priceMYR 464
Off-season for travelJanuary
Peak season for travelMay
Flight distance3,054.23 km
Popular airlineAlaska Airlines

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