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Cheap flight deals from Knoxville to Sioux Falls Starting at PHP 5,573

For as little as PHP 5,573, you can take your next adventure to Sioux Falls without breaking the bank. Choose between one-way and return tickets from Knoxville below.

  • One way
  • Round-trip
      • TYS16:23
        22h 29m
        1 stop
        FSD13:52
        Thu, Mar 20|Knoxville - Sioux Falls|Frontier Airlines
        PHP 5,573PHP 37,657
        85% OFF
        85% OFF
        PHP 37,657PHP 5,573

        Choose Frontier Airlines flights from Knoxville to Sioux Falls. The one-way connecting flight with Frontier Airlines departs from Mcghee Tyson Airport on Thu, Mar 20, arriving at Sioux Falls Regional Airport. One-way Prices start from PHP 5,573 including taxes and charges.

      • TYS07:00
        4h 39m
        1 stop
        FSD10:39
        Sat, Apr 5|Knoxville - Sioux Falls|United Airlines
        PHP 10,747PHP 37,657
        71% OFF
        71% OFF
        PHP 37,657PHP 10,747

        Choose United Airlines flights from Knoxville to Sioux Falls. The one-way connecting flight with United Airlines departs from Mcghee Tyson Airport on Sat, Apr 5, arriving at Sioux Falls Regional Airport. One-way Prices start from PHP 10,747 including taxes and charges.

      • TYS16:43
        22h 2m
        1 stop
        FSD13:45
        Sun, Mar 16|Knoxville - Sioux Falls|Frontier Airlines
        PHP 12,455PHP 37,657
        67% OFF
        67% OFF
        PHP 37,657PHP 12,455

        Choose Frontier Airlines flights from Knoxville to Sioux Falls. The one-way connecting flight with Frontier Airlines departs from Mcghee Tyson Airport on Sun, Mar 16, arriving at Sioux Falls Regional Airport. One-way Prices start from PHP 12,455 including taxes and charges.

      • TYS06:45
        4h 26m
        1 stop
        FSD10:11
        Thu, Mar 20|Knoxville - Sioux Falls|Delta Air Lines
        PHP 12,862
        PHP 12,862

        Choose Delta Air Lines flights from Knoxville to Sioux Falls. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Thu, Mar 20, arriving at Sioux Falls Regional Airport. One-way Prices start from PHP 12,862 including taxes and charges.

      • TYS17:25
        5h 50m
        1 stop
        FSD22:15
        Thu, Mar 20|Knoxville - Sioux Falls|United Airlines
        PHP 14,874
        PHP 14,874

        Choose United Airlines flights from Knoxville to Sioux Falls. The one-way connecting flight with United Airlines departs from Mcghee Tyson Airport on Thu, Mar 20, arriving at Sioux Falls Regional Airport. One-way Prices start from PHP 14,874 including taxes and charges.

      • TYS18:50
        4h 52m
        1 stop
        FSD22:42
        Tue, Mar 18|Knoxville - Sioux Falls|American Airlines
        PHP 14,938
        PHP 14,938

        Choose American Airlines flights from Knoxville to Sioux Falls. The one-way connecting flight with American Airlines departs from Mcghee Tyson Airport on Tue, Mar 18, arriving at Sioux Falls Regional Airport. One-way Prices start from PHP 14,938 including taxes and charges.

      • TYS05:15
        7h 36m
        1 stop
        FSD11:51
        Sat, Apr 5|Knoxville - Sioux Falls|American Airlines
        PHP 19,250
        PHP 19,250

        Choose American Airlines flights from Knoxville to Sioux Falls. The one-way connecting flight with American Airlines departs from Mcghee Tyson Airport on Sat, Apr 5, arriving at Sioux Falls Regional Airport. One-way Prices start from PHP 19,250 including taxes and charges.

      • TYS17:08
        7h 8m
        1 stop
        FSD23:16
        Sat, Apr 5|Knoxville - Sioux Falls|Delta Air Lines
        PHP 24,527
        PHP 24,527

        Choose Delta Air Lines flights from Knoxville to Sioux Falls. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Sat, Apr 5, arriving at Sioux Falls Regional Airport. One-way Prices start from PHP 24,527 including taxes and charges.

      • TYS07:00
        16h 15m
        1 stop
        FSD22:15
        Sun, Mar 16|Knoxville - Sioux Falls|United Airlines
        PHP 29,517
        PHP 29,517

        Choose United Airlines flights from Knoxville to Sioux Falls. The one-way connecting flight with United Airlines departs from Mcghee Tyson Airport on Sun, Mar 16, arriving at Sioux Falls Regional Airport. One-way Prices start from PHP 29,517 including taxes and charges.

      • TYS06:45
        17h 14m
        1 stop
        FSD22:59
        Sun, Mar 16|Knoxville - Sioux Falls|Delta Air Lines
        PHP 34,267
        PHP 34,267

        Choose Delta Air Lines flights from Knoxville to Sioux Falls. The one-way connecting flight with Delta Air Lines departs from Mcghee Tyson Airport on Sun, Mar 16, arriving at Sioux Falls Regional Airport. One-way Prices start from PHP 34,267 including taxes and charges.

      • TYS01:00 pm
        3h 5m
        Nonstop
        FSD02:00 pm
        Thu, Feb 27|Knoxville - Sioux Falls|Frontier Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Knoxville to Sioux Falls flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. DL3015

    Delta Air Lines

    05:30

    TYS

    1.0h

    06:29

    ATL

    SMTWTFS
    Search

  2. DL2960

    Delta Air Lines

    08:55

    ATL

    2.7h

    10:36

    MSP

    SMTWTFS

  3. DL5234

    Delta Air Lines

    11:20

    MSP

    1.1h

    12:27

    FSD

    SMTWTFS

  4. DL5523

    Delta Air Lines

    06:45

    TYS

    2.5h

    08:15

    MSP

    SMTWTFS
    Search

  5. DL5234

    Delta Air Lines

    11:20

    MSP

    1.1h

    12:27

    FSD

    SMTWTFS

  6. DL5523

    Delta Air Lines

    06:45

    TYS

    2.5h

    08:15

    MSP

    SMTWTFS
    Search

  7. DL5261

    Delta Air Lines

    08:50

    MSP

    1.1h

    09:54

    FSD

    SMTWTFS

  8. UA2046

    United Airlines

    07:00

    TYS

    2.0h

    08:03

    ORD

    SMTWTFS
    Search

  9. UA2113

    United Airlines

    20:20

    ORD

    1.9h

    22:12

    FSD

    SMTWTFS

  10. UA2046

    United Airlines

    07:00

    TYS

    2.0h

    08:03

    ORD

    SMTWTFS
    Search

  11. UA5314

    United Airlines

    08:45

    ORD

    1.9h

    10:39

    FSD

    SMTWTFS

  12. UA5610

    United Airlines

    16:20

    TYS

    3.9h

    18:11

    DEN

    SMTWTFS
    Search

  13. UA5700

    United Airlines

    21:02

    DEN

    1.7h

    23:45

    FSD

    SMTWTFS

  14. UA5305

    United Airlines

    17:35

    TYS

    2.0h

    18:37

    ORD

    SMTWT--
    Search

  15. UA2113

    United Airlines

    20:20

    ORD

    1.9h

    22:12

    FSD

    SMTWTFS
Find more flights and airlines

When is the cheapest time to fly from Knoxville to Sioux Falls?

Price trend charts are a great way of tracking how much your flights cost in the lead up to departure and can help you choose when to book your tickets. See how prices to Sioux Falls from Knoxville have changed and are set to move below.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Knoxville (TYS) to Sioux Falls (FSD) the cheapest?

    Airlines adjust prices for flights from Knoxville to Sioux Falls based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Knoxville (TYS) to Sioux Falls (FSD) cost?

    According to Trip.com's data, the lowest price is around PHP 28,255.

  • What is the transportation method from the main airport to downtown in Sioux Falls?

    • The distance from Sioux Falls Regional Airport to downtown is about 3 km, by taxi about 20 minutes.

  • How many airports are there in Sioux Falls (FSD)?

    There are 1 airport(s) near Sioux Falls (FSD): Sioux Falls Regional Airport.

How to find a cheap flight from Knoxville to Sioux Falls

If you leave it until the last minute and forget to check some of the key information when booking tickets, prices can often end up skyrocketing. Below, you can find our top tips for getting the best value flights – from changing dates to chasing deals, there are plenty ways to keep your next trip affordable.
1
Being flexible with your dates to get the cheapest Knoxville to Sioux Falls ticket.
Tap "Date" on flight search bar to scan through the calender for Knoxville to Sioux Falls airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Thu, Mar 20 at PHP 5573 for one-way flights.
2
Compare cheap Knoxville to Sioux Falls flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from Knoxville to Sioux Falls. The cheapest airline operating is Frontier Airlines.
3
Set up a Price Alert
By setting up a Price Alert for your Knoxville to Sioux Falls route, you can easily track the price of your airline tickets from without manually checking every day.
4
Don't miss cheap Knoxville to Sioux Falls flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights. If registering a free membership, you can receive more deals for your flights.
5
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
6
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com and search for cheap flight tickets from Knoxville to Sioux Falls to get exclusive deals for you.

Flight Info | Knoxville to Sioux Falls

Cheapest direct flight pricePHP 5,572
Off-season for travelFebruary
Peak season for travelNovember
Flight distance1,388.73 km
Popular airlineDelta Air Lines

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