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Flights from Mayaguez to Santo Domingo

Cheap flight deals from Mayaguez to Santo Domingo

We've found these cheap flights for you. You can book one-way or round-trip flight tickets.

  • Round-trip
  • One way

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

When is the cheapest time to fly from Mayaguez to Santo Domingo?

We monitor flight fares to help you find the best deals effortlessly

Cheapest flights
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  • 6 13
  • 13 20
  • 20 27

  • May

    27 4
  • 4 11
  • 11 18
  • 18 25

  • Jun

    25 1
  • 1 8
  • 8 15
  • 15 22
  • 22 29
Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Mayaguez (MAZ) to Santo Domingo (SDQ) the cheapest?

    Airlines adjust prices for flights from Mayaguez to Santo Domingo based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Mayaguez (MAZ) to Santo Domingo (SDQ) cost?

    According to Trip.com's data, the lowest price is around AED 4,612.

  • How many airports are there in Santo Domingo (SDQ)?

    There are 2 airport(s) near Santo Domingo (SDQ): La Isabela International Airport and Las Américas International Airport.

How to find a cheap flight from Mayaguez to Santo Domingo

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Mayaguez to Santo Domingo. Book your flights at the right time and save more.
1
Being flexible with your dates to get the cheapest Mayaguez to Santo Domingo ticket.
Tap "Date" on flight search bar to get the calender for Mayaguez to Santo Domingo airfare over next 6 months in 2025.
2
Compare cheap Mayaguez to Santo Domingo flight deals from over hundreds of airlines.
Compare prices from over 500 airlines with our powerful search and find the cheapest flight tickets from Mayaguez to Santo Domingo.
3
Set up a Price Alert
By setting up a Price Alert for your Mayaguez to Santo Domingo route, you can easily track the price of your airline tickets from without manually checking every day.
4
Don't miss cheap Mayaguez to Santo Domingo flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights. If registering a free membership, you can receive more deals for your flights.
5
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
6
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com and search for cheap flight tickets from Mayaguez to Santo Domingo to get exclusive deals for you.

Flight Info | Mayaguez to Santo Domingo

Off-season for travel April
Peak season for travel March
Flight distance 291.31 km
Popular airline United Airlines

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