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Cheap flight deals from Medellin to Guayaquil Starting at AED 458

For as little as AED 458, you can take your next adventure to Guayaquil without breaking the bank. Choose between one-way and return tickets from Medellin below.

  • One way
  • Round-trip
      • Cheapest nonstop
        MDE16:55
        1h 50m
        Nonstop
        GYE18:45
        Fri, Mar 28|Medellin - Guayaquil|avianca
        AED 458AED 815
        44% OFF
        44% OFF
        AED 815AED 458

        Choose avianca flights from Medellin to Guayaquil. The one-way direct flight with avianca departs from Jose Marie Cordova Airport on Fri, Mar 28, arriving at Jose Joaquin De Olmedo International Airport. One-way Prices start from AED 458 including taxes and charges.

      • MDE16:55
        1h 50m
        Nonstop
        GYE18:45
        Fri, Apr 4|Medellin - Guayaquil|avianca
        AED 472AED 815
        42% OFF
        42% OFF
        AED 815AED 472

        Choose avianca flights from Medellin to Guayaquil. The one-way direct flight with avianca departs from Jose Marie Cordova Airport on Fri, Apr 4, arriving at Jose Joaquin De Olmedo International Airport. One-way Prices start from AED 472 including taxes and charges.

      • MDE16:55
        1h 50m
        Nonstop
        GYE18:45
        Fri, Mar 7|Medellin - Guayaquil|avianca
        AED 485AED 815
        40% OFF
        40% OFF
        AED 815AED 485

        Choose avianca flights from Medellin to Guayaquil. The one-way direct flight with avianca departs from Jose Marie Cordova Airport on Fri, Mar 7, arriving at Jose Joaquin De Olmedo International Airport. One-way Prices start from AED 485 including taxes and charges.

      • MDE16:55
        1h 50m
        Nonstop
        GYE18:45
        Fri, Feb 21|Medellin - Guayaquil|avianca
        AED 603
        AED 603

        Choose avianca flights from Medellin to Guayaquil. The one-way direct flight with avianca departs from Jose Marie Cordova Airport on Fri, Feb 21, arriving at Jose Joaquin De Olmedo International Airport. One-way Prices start from AED 603 including taxes and charges.

      • MDE17:40
        5h 57m
        1 stop
        GYE23:37
        Thu, Mar 27|Medellin - Guayaquil|avianca
        AED 477
        AED 477

        Choose avianca flights from Medellin to Guayaquil. The one-way connecting flight with avianca departs from Jose Marie Cordova Airport on Thu, Mar 27, arriving at Jose Joaquin De Olmedo International Airport. One-way Prices start from AED 477 including taxes and charges.

      • MDE17:19
        5h 21m
        1 stop
        GYE22:40
        Sun, Mar 16|Medellin - Guayaquil|avianca
        AED 478
        AED 478

        Choose avianca flights from Medellin to Guayaquil. The one-way connecting flight with avianca departs from Jose Marie Cordova Airport on Sun, Mar 16, arriving at Jose Joaquin De Olmedo International Airport. One-way Prices start from AED 478 including taxes and charges.

      • MDE07:16
        5h 29m
        1 stop
        GYE12:45
        Sat, Mar 29|Medellin - Guayaquil|avianca
        AED 480
        AED 480

        Choose avianca flights from Medellin to Guayaquil. The one-way connecting flight with avianca departs from Jose Marie Cordova Airport on Sat, Mar 29, arriving at Jose Joaquin De Olmedo International Airport. One-way Prices start from AED 480 including taxes and charges.

      • MDE18:29
        4h 11m
        1 stop
        GYE22:40
        Wed, Mar 26|Medellin - Guayaquil|avianca
        AED 481
        AED 481

        Choose avianca flights from Medellin to Guayaquil. The one-way connecting flight with avianca departs from Jose Marie Cordova Airport on Wed, Mar 26, arriving at Jose Joaquin De Olmedo International Airport. One-way Prices start from AED 481 including taxes and charges.

      • MDE16:12
        6h 28m
        1 stop
        GYE22:40
        Mon, Apr 7|Medellin - Guayaquil|avianca
        AED 481
        AED 481

        Choose avianca flights from Medellin to Guayaquil. The one-way connecting flight with avianca departs from Jose Marie Cordova Airport on Mon, Apr 7, arriving at Jose Joaquin De Olmedo International Airport. One-way Prices start from AED 481 including taxes and charges.

      • MDE04:35
        4h 25m
        1 stop
        GYE09:00
        Sun, Mar 23|Medellin - Guayaquil|avianca
        AED 481
        AED 481

        Choose avianca flights from Medellin to Guayaquil. The one-way connecting flight with avianca departs from Jose Marie Cordova Airport on Sun, Mar 23, arriving at Jose Joaquin De Olmedo International Airport. One-way Prices start from AED 481 including taxes and charges.

      • MDE01:00 pm
        3h 5m
        Nonstop
        GYE02:00 pm
        Fri, Feb 28|Medellin - Guayaquil|avianca
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Medellin to Guayaquil flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. AV9653

    avianca

    04:28

    MDE

    1.0h

    05:27

    BOG

    S------
    Search

  2. AV8385

    avianca

    07:10

    BOG

    1.8h

    09:00

    GYE

    SMTWTFS

  3. AV8475

    avianca

    05:08

    MDE

    1.0h

    06:10

    BOG

    --TWT--
    Search

  4. AV077

    avianca

    08:00

    BOG

    1.8h

    09:50

    GYE

    SMTWTFS

  5. AV9245

    avianca

    05:27

    MDE

    1.0h

    06:29

    BOG

    SMTWTFS
    Search

  6. AV091

    avianca

    08:00

    BOG

    1.9h

    09:55

    GYE

    -M-----

  7. AV8415

    avianca

    05:58

    MDE

    1.0h

    07:00

    BOG

    SMTWTFS
    Search

  8. AV8391

    avianca

    21:25

    BOG

    1.9h

    23:20

    GYE

    SMTWTFS

  9. AV9463

    avianca

    07:58

    MDE

    0.9h

    08:54

    BOG

    SMTWTFS
    Search

  10. AV077

    avianca

    08:00

    BOG

    1.8h

    09:50

    GYE

    SMTWTFS

  11. AV9323

    avianca

    08:51

    MDE

    0.9h

    09:47

    BOG

    SMTWTFS
    Search

  12. AV8389

    avianca

    11:50

    BOG

    1.8h

    13:40

    GYE

    -M-W-FS

  13. AV8399

    avianca

    16:55

    MDE

    1.8h

    Nonstop

    18:45

    GYE

    S-T-T--
    Search

  14. AV9309

    avianca

    17:30

    MDE

    0.9h

    18:26

    BOG

    -M-W-F-
    Search

  15. AV8371

    avianca

    20:50

    BOG

    1.8h

    22:40

    GYE

    S-TWTFS

  16. AV9375

    avianca

    18:57

    MDE

    1.0h

    19:55

    BOG

    SMTWTFS
    Search

  17. AV8391

    avianca

    21:25

    BOG

    1.9h

    23:20

    GYE

    SMTWTFS

  18. AV9375

    avianca

    18:57

    MDE

    1.0h

    19:55

    BOG

    SMTWTFS
    Search

  19. AV8371

    avianca

    20:50

    BOG

    1.8h

    22:40

    GYE

    S-TWTFS
Find more flights and airlines

When is the cheapest time to fly from Medellin to Guayaquil?

These price trend charts carefully monitor and predict how flight prices from Medellin to Guayaquil will change. Keep a close eye on them to understand when the best time to buy your tickets is.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Medellin (MDE) to Guayaquil (GYE) the cheapest?

    Airlines adjust prices for flights from Medellin to Guayaquil based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Medellin (MDE) to Guayaquil (GYE) cost?

    According to Trip.com's data, the lowest price is around AED 960.

  • How long does it take to fly from Medellin (MDE) to Guayaquil (GYE)?

    It takes about 1 hour 50 minutes to fly from Medellin (MDE) to Guayaquil (GYE).

  • What is the transportation method from the main airport to downtown in Guayaquil?

    • The distance from Jose Joaquin De Olmedo International Airport to downtown is about 4 km, by taxi about 20 minutes.

  • What are the most popular airlines that fly from Medellin (MDE) to Guayaquil (GYE)?

    Airlines with flights from Medellin (MDE) to Guayaquil (GYE): avianca.

  • How many airports are there in Guayaquil (GYE)?

    There are 1 airport(s) near Guayaquil (GYE): Jose Joaquin De Olmedo International Airport.

How to find a cheap flight from Medellin to Guayaquil

If you leave it until the last minute and forget to check some of the key information when booking tickets, prices can often end up skyrocketing. Below, you can find our top tips for getting the best value flights – from changing dates to chasing deals, there are plenty ways to keep your next trip affordable.
1
Being flexible with your dates to get the cheapest Medellin to Guayaquil ticket.
Tap "Date" on flight search bar to scan through the calender for Medellin to Guayaquil airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Fri, Mar 28 at AED 458 for one-way flights.
2
Compare cheap Medellin to Guayaquil flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from Medellin to Guayaquil. The cheapest airline operating is avianca.
3
Set up a Price Alert
By setting up a Price Alert for your Medellin to Guayaquil route, you can easily track the price of your airline tickets from without manually checking every day.
4
Don't miss cheap Medellin to Guayaquil flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights. If registering a free membership, you can receive more deals for your flights.
5
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
6
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com and search for cheap flight tickets from Medellin to Guayaquil to get exclusive deals for you.

Flight Info | Medellin to Guayaquil

Cheapest direct flight priceAED 457
Cheapest return ticket priceAED 798
Off-season for travelJanuary
Peak season for travelMay
Flight distance1,048.08 km
Average flight time1 hour 50 minutes
Popular airlineavianca

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