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Flights from Mexico City to Santa Cruz
Cheap flight deals from Mexico City to Santa Cruz
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
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Round-trip
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One way
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MEX 04:5518h 55m1 stopsVVI 01:50Mexico City - Santa Cruz | Fri, May 30 | aviancaVVI 02:5522h 5m1 stopsMEX 23:00Santa Cruz - Mexico City | Wed, Jun 4 | aviancaAED 1,559 AED 1,74611% OFF11% OFFAED 1,746 AED 1,559
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MEX 00:4023h 10m1 stopsVVI 01:50Mexico City - Santa Cruz | Mon, Jun 2 | aviancaVVI 02:5522h 5m1 stopsMEX 23:00Santa Cruz - Mexico City | Fri, Jun 6 | aviancaAED 1,605 AED 1,7468% OFF8% OFFAED 1,746 AED 1,605
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MEX 00:4023h 10m1 stopsVVI 01:50Mexico City - Santa Cruz | Thu, Jun 5 | aviancaVVI 02:5511h 10m1 stopsMEX 12:05Santa Cruz - Mexico City | Sun, Jun 8 | aviancaAED 1,611 AED 1,7468% OFF8% OFFAED 1,746 AED 1,611
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MEX 04:5518h 55m1 stopsVVI 01:50Mexico City - Santa Cruz | Mon, Jun 9 | aviancaVVI 02:5517h 10m1 stopsMEX 18:05Santa Cruz - Mexico City | Mon, Jun 16 | aviancaAED 1,6158% OFFAED 1,746 AED 1,615
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MEX 04:5518h 55m1 stopsVVI 01:50Mexico City - Santa Cruz | Tue, May 27 | aviancaVVI 02:5511h 10m1 stopsMEX 12:05Santa Cruz - Mexico City | Tue, Jun 3 | aviancaAED 1,6217% OFFAED 1,746 AED 1,621
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MEX 04:5518h 55m1 stopsVVI 01:50Mexico City - Santa Cruz | Sat, Jun 14 | aviancaVVI 02:5522h 5m1 stopsMEX 23:00Santa Cruz - Mexico City | Tue, Jun 17 | aviancaAED 1,6227% OFFAED 1,746 AED 1,622
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MEX 04:5518h 55m1 stopsVVI 01:50Mexico City - Santa Cruz | Fri, Jun 13 | aviancaVVI 02:5517h 10m1 stopsMEX 18:05Santa Cruz - Mexico City | Wed, Jun 18 | aviancaAED 1,6227% OFFAED 1,746 AED 1,622
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MEX 14:009h 50m1 stopsVVI 01:50Mexico City - Santa Cruz | Tue, Jun 10 | aviancaVVI 02:5522h 5m1 stopsMEX 23:00Santa Cruz - Mexico City | Tue, Jun 17 | aviancaAED 1,6237% OFFAED 1,746 AED 1,623
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MEX 14:009h 50m1 stopsVVI 01:50Mexico City - Santa Cruz | Thu, May 29 | aviancaVVI 02:5511h 10m1 stopsMEX 12:05Santa Cruz - Mexico City | Thu, Jun 5 | aviancaAED 1,6237% OFFAED 1,746 AED 1,623
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MEX 04:5518h 55m1 stopsVVI 01:50Mexico City - Santa Cruz | Fri, Jun 6 | aviancaVVI 02:5522h 5m1 stopsMEX 23:00Santa Cruz - Mexico City | Wed, Jun 11 | aviancaAED 1,6247% OFFAED 1,746 AED 1,624
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MEX 13:0017h 25m1 stopsSRZ Invalid DateMexico City - Santa Cruz | Tue, May 27 | Normal AirlineSRZ 15:006hNonstopMEX 16:00Santa Cruz - Mexico City | Thu, May 29 | Normal AirlineFind More FlightsFind More Flights
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MEX 14:009h 50m1 stopsVVI 01:50Mexico City - Santa Cruz | Tue, Jun 10 | aviancaAED 715 AED 85116% OFF16% OFFAED 851 AED 715
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MEX 00:4023h 10m1 stopsVVI 01:50Mexico City - Santa Cruz | Fri, May 30 | aviancaAED 755 AED 85111% OFF11% OFFAED 851 AED 755
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MEX 04:5518h 55m1 stopsVVI 01:50Mexico City - Santa Cruz | Sat, Jun 14 | aviancaAED 759 AED 85111% OFF11% OFFAED 851 AED 759
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MEX 04:5518h 55m1 stopsVVI 01:50Mexico City - Santa Cruz | Mon, Jun 2 | aviancaAED 7828% OFFAED 851 AED 782
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MEX 14:009h 50m1 stopsVVI 01:50Mexico City - Santa Cruz | Tue, Jun 3 | aviancaAED 7868% OFFAED 851 AED 786
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MEX 04:5518h 55m1 stopsVVI 01:50Mexico City - Santa Cruz | Wed, Jun 18 | aviancaAED 7897% OFFAED 851 AED 789
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MEX 14:009h 50m1 stopsVVI 01:50Mexico City - Santa Cruz | Wed, Jun 4 | aviancaAED 7897% OFFAED 851 AED 789
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MEX 04:5518h 55m1 stopsVVI 01:50Mexico City - Santa Cruz | Sun, Jun 1 | aviancaAED 7897% OFFAED 851 AED 789
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MEX 00:4023h 10m1 stopsVVI 01:50Mexico City - Santa Cruz | Sat, Jun 7 | aviancaAED 7917% OFFAED 851 AED 791
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MEX 04:5518h 55m1 stopsVVI 01:50Mexico City - Santa Cruz | Thu, May 29 | aviancaAED 7927% OFFAED 851 AED 792
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MEX 13:0017h 25m1 stopsSRZ Invalid DateMexico City - Santa Cruz | Tue, May 27 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
Flight Info | Mexico City to Santa Cruz
Cheapest one-way flight price | AED 714 |
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Off-season for travel | March |
Peak season for travel | February |
Flight distance | 5,702.49 km |
Popular airline | Aeromexico |
When is the cheapest time to fly from Mexico City to Santa Cruz?
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Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Frequently Asked Questions
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When are flight tickets from Mexico City (MEX) to Santa Cruz (SRZ) the cheapest?
Airlines adjust prices for flights from Mexico City to Santa Cruz based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much do flights from Mexico City (MEX) to Santa Cruz (SRZ) cost?
According to Trip.com's data, the lowest price is around AED 2,574. -
How many airports are there in Santa Cruz (SRZ)?
There are 1 airport(s) near Santa Cruz (SRZ): Viru Viru International Airport.
How to find a cheap flight from Mexico City to Santa Cruz
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Mexico City to Santa Cruz. Book your flights at the right time and save more.
Being flexible with your dates to get the cheapest Mexico City to Santa Cruz ticket.
Tap "Date" on flight search bar to scan through the calender for Mexico City to Santa Cruz airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Tue, Jun 10 at AED 715 for one-way flights.
Compare cheap Mexico City to Santa Cruz flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from Mexico City to Santa Cruz. The cheapest airline operating is avianca.
Set up a Price Alert
By setting up a Price Alert for your Mexico City to Santa Cruz route, you can easily track the price of your airline tickets from without manually checking every day.
Don't miss cheap Mexico City to Santa Cruz flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights. If registering a free membership, you can receive more deals for your flights.
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com and search for cheap flight tickets from Mexico City to Santa Cruz to get exclusive deals for you.
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