Cheap flight deals from Mexico City to Santiago

We've found these cheap flights for you. You can book one-way or round-trip flight tickets.

  • Round-trip
  • One way

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

When is the cheapest time to fly from Mexico City to Santiago?

We monitor flight fares to help you find the best deals effortlessly

Cheapest flights
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  • Apr

    30 6
  • 6 13
  • 13 20
  • 20 27

  • May

    27 4
  • 4 11
  • 11 18
  • 18 25

  • Jun

    25 1
  • 1 8
  • 8 15
  • 15 22
Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Mexico City (MEX) to Santiago (SCU) the cheapest?

    Airlines adjust prices for flights from Mexico City to Santiago based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Mexico City (MEX) to Santiago (SCU) cost?

    According to Trip.com's data, the lowest price is around AED 2,551.

  • What is the transportation method from the main airport to downtown in Santiago?

    • The distance from Antonio Maceo International Airport to downtown is about 27 km, by taxi about 40 minutes.

  • How many airports are there in Santiago (SCU)?

    There are 1 airport(s) near Santiago (SCU): Antonio Maceo International Airport.

How to find a cheap flight from Mexico City to Santiago

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Mexico City to Santiago. Book your flights at the right time and save more.
1
Being flexible with your dates to get the cheapest Mexico City to Santiago ticket.
Tap "Date" on flight search bar to scan through the calender for Mexico City to Santiago airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Mon, Apr 28 at AED 1584 for one-way flights.
2
Compare cheap Mexico City to Santiago flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from Mexico City to Santiago. The cheapest airline operating is Aeromexico.
3
Set up a Price Alert
By setting up a Price Alert for your Mexico City to Santiago route, you can easily track the price of your airline tickets from without manually checking every day.
4
Don't miss cheap Mexico City to Santiago flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights. If registering a free membership, you can receive more deals for your flights.
5
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
6
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com and search for cheap flight tickets from Mexico City to Santiago to get exclusive deals for you.

Flight Info | Mexico City to Santiago

Cheapest one-way flight price AED 1,584
Off-season for travel March
Peak season for travel May
Flight distance 2,432.53 km
Popular airline Aeromexico

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