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Flights from Mexico City to Santiago
Cheap flight deals from Mexico City to Santiago Starting at AED 1,123
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
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Round-trip
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One way
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MEX 07:5514h 50m1 stopsSTI 00:45Mexico City - Santiago | Fri, Mar 21 | United AirlinesSTI 03:3918h 36m1 stopsMEX 20:15Santiago - Mexico City | Mon, Mar 24 | Jetblue AirwaysAED 2,313 AED 3,22728% OFF28% OFFAED 3,227 AED 2,313
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MEX 13:3515h 40m1 stopsSTI 07:15Mexico City - Santiago | Thu, Apr 3 | Delta Air LinesSTI 08:2812h 32m1 stopsMEX 19:00Santiago - Mexico City | Thu, Apr 10 | Jetblue AirwaysAED 2,598 AED 3,22719% OFF19% OFFAED 3,227 AED 2,598
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MEX 10:5018h 25m1 stopsSTI 07:15Mexico City - Santiago | Thu, Apr 3 | AeromexicoSTI 08:2812h 32m1 stopsMEX 19:00Santiago - Mexico City | Thu, Apr 10 | Jetblue AirwaysAED 2,623 AED 3,22719% OFF19% OFFAED 3,227 AED 2,623
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MEX 13:3515h 40m1 stopsSTI 07:15Mexico City - Santiago | Mon, Mar 31 | AeromexicoSTI 08:1513h 15m1 stopsMEX 19:30Santiago - Mexico City | Fri, Apr 4 | Jetblue AirwaysAED 2,68517% OFFAED 3,227 AED 2,685
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MEX 06:4523h 43m1 stopsSTI 08:28Mexico City - Santiago | Thu, Mar 27 | AeromexicoSTI 08:1516h1 stopsMEX 22:15Santiago - Mexico City | Thu, Apr 3 | Jetblue AirwaysAED 2,79813% OFFAED 3,227 AED 2,798
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MEX 23:2018h 30m1 stopsSTI 19:50Mexico City - Santiago | Mon, Apr 28 | American AirlinesSTI 02:1122h 9m1 stopsMEX 22:20Santiago - Mexico City | Mon, May 5 | Jetblue AirwaysAED 2,83712% OFFAED 3,227 AED 2,837
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MEX 00:2521h 21m1 stopsSTI 23:46Mexico City - Santiago | Fri, Mar 14 | American AirlinesSTI 01:5522h 25m1 stopsMEX 22:20Santiago - Mexico City | Fri, Mar 21 | Jetblue AirwaysAED 2,9469% OFFAED 3,227 AED 2,946
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MEX 00:2513h 55m1 stopsSTI 16:20Mexico City - Santiago | Mon, Mar 24 | American AirlinesSTI 04:1520h 5m1 stopsMEX 22:20Santiago - Mexico City | Sun, Mar 30 | Jetblue AirwaysAED 2,9538% OFFAED 3,227 AED 2,953
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MEX 13:3515h 40m1 stopsSTI 07:15Mexico City - Santiago | Fri, Apr 4 | AeromexicoSTI 08:289h 12m1 stopsMEX 15:40Santiago - Mexico City | Fri, Apr 11 | Jetblue AirwaysAED 2,9648% OFFAED 3,227 AED 2,964
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MEX 07:1514h 8m1 stopsSTI 23:23Mexico City - Santiago | Thu, Mar 13 | Viva AerobusSTI 01:5518h 40m1 stopsMEX 18:35Santiago - Mexico City | Fri, Mar 21 | Jetblue AirwaysAED 3,0346% OFFAED 3,227 AED 3,034
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MEX 13:0017h 25m1 stopsSTI Invalid DateMexico City - Santiago | Fri, Mar 14 | Normal AirlineSTI 15:006hNonstopMEX 16:00Santiago - Mexico City | Sun, Mar 16 | Normal AirlineFind More FlightsFind More Flights
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MEX 11:1019h 18m1 stopsSTI 08:28Mexico City - Santiago | Thu, Mar 20 | VolarisAED 1,123 AED 1,53527% OFF27% OFFAED 1,535 AED 1,123
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MEX 11:0518h 10m1 stopsSTI 07:15Mexico City - Santiago | Wed, Apr 2 | VolarisAED 1,208 AED 1,53521% OFF21% OFFAED 1,535 AED 1,208
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MEX 06:4523h 43m1 stopsSTI 08:28Mexico City - Santiago | Thu, Mar 20 | AeromexicoAED 1,211 AED 1,53521% OFF21% OFFAED 1,535 AED 1,211
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MEX 00:2530h 11m1 stopsSTI 08:36Mexico City - Santiago | Wed, Mar 12 | American AirlinesAED 1,21921% OFFAED 1,535 AED 1,219
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MEX 11:1019h 18m1 stopsSTI 08:28Mexico City - Santiago | Fri, Mar 21 | VolarisAED 1,36411% OFFAED 1,535 AED 1,364
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MEX 11:0518h 13m1 stopsSTI 07:18Mexico City - Santiago | Tue, May 6 | VolarisAED 1,37011% OFFAED 1,535 AED 1,370
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MEX 11:1019h 18m1 stopsSTI 08:28Mexico City - Santiago | Tue, Mar 18 | VolarisAED 1,4188% OFFAED 1,535 AED 1,418
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MEX 07:1516h 29m1 stopsSTI 01:44Mexico City - Santiago | Thu, Mar 20 | Viva AerobusAED 1,4237% OFFAED 1,535 AED 1,423
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MEX 07:1514h 20m1 stopsSTI 23:35Mexico City - Santiago | Wed, Apr 2 | Viva AerobusAED 1,4257% OFFAED 1,535 AED 1,425
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MEX 07:1525h 56m1 stopsSTI 11:11Mexico City - Santiago | Wed, Mar 12 | Viva AerobusAED 1,4436% OFFAED 1,535 AED 1,443
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MEX 13:0017h 25m1 stopsSTI Invalid DateMexico City - Santiago | Fri, Mar 14 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
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Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Frequently Asked Questions
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When are flight tickets from Mexico City (MEX) to Santiago (STI) the cheapest?
Airlines adjust prices for flights from Mexico City to Santiago based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much do flights from Mexico City (MEX) to Santiago (STI) cost?
According to Trip.com's data, the lowest price is around AED 2,709. -
What is the transportation method from the main airport to downtown in Santiago?
- The distance from Cibao International Airport to downtown is about 12 km, by taxi about 30 minutes.
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How many airports are there in Santiago (STI)?
There are 1 airport(s) near Santiago (STI): Cibao International Airport.
How to find a cheap flight from Mexico City to Santiago
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Mexico City to Santiago. Book your flights at the right time and save more.
Being flexible with your dates to get the cheapest Mexico City to Santiago ticket.
Tap "Date" on flight search bar to scan through the calender for Mexico City to Santiago airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Thu, Mar 20 at AED 1123 for one-way flights.
Compare cheap Mexico City to Santiago flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from Mexico City to Santiago. The cheapest airline operating is Volaris.
Set up a Price Alert
By setting up a Price Alert for your Mexico City to Santiago route, you can easily track the price of your airline tickets from without manually checking every day.
Don't miss cheap Mexico City to Santiago flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights. If registering a free membership, you can receive more deals for your flights.
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com and search for cheap flight tickets from Mexico City to Santiago to get exclusive deals for you.
Flight Info | Mexico City to Santiago
Cheapest direct flight price | AED 1,122 |
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Off-season for travel | January |
Peak season for travel | May |
Flight distance | 2,983.05 km |
Popular airline | Aeromexico |
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