App
Customer Support
EUR
Find Bookings
Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Cheap flight deals from Palermo to Sao Tome Island Starting at €717

Whether you’re going for a one-way or round-trip to Sao Tome Island, we’ve got you covered! Check out these different flight options from Palermo below.

  • One way
  • Round-trip
      • PMO10:05
        32h 50m
        2 stops
        TMS17:55
        Sat, Mar 1|Palermo - Sao Tome Island|TAP Air Portugal
        €717€1,223
        41% OFF
        41% OFF
        €1,223€717

        Choose TAP Air Portugal flights from Palermo to Sao Tome Island. The one-way connecting flight with TAP Air Portugal departs from Falcone-Borsellino International Airport on Sat, Mar 1, arriving at São Tomé International Airport. One-way Prices start from €717 including taxes and charges.

      • PMO15:15
        27h 40m
        2 stops
        TMS17:55
        Sat, Mar 1|Palermo - Sao Tome Island|ITA Airways
        €749€1,223
        39% OFF
        39% OFF
        €1,223€749

        Choose ITA Airways flights from Palermo to Sao Tome Island. The one-way connecting flight with ITA Airways departs from Falcone-Borsellino International Airport on Sat, Mar 1, arriving at São Tomé International Airport. One-way Prices start from €749 including taxes and charges.

      • PMO14:50
        28h 5m
        2 stops
        TMS17:55
        Sat, Mar 1|Palermo - Sao Tome Island|Swiss Airlines
        €807€1,223
        34% OFF
        34% OFF
        €1,223€807

        Choose Swiss Airlines flights from Palermo to Sao Tome Island. The one-way connecting flight with Swiss Airlines departs from Falcone-Borsellino International Airport on Sat, Mar 1, arriving at São Tomé International Airport. One-way Prices start from €807 including taxes and charges.

      • PMO06:10
        36h 45m
        2 stops
        TMS17:55
        Sat, Mar 8|Palermo - Sao Tome Island|TAP Air Portugal
        €847
        €847

        Choose TAP Air Portugal flights from Palermo to Sao Tome Island. The one-way connecting flight with TAP Air Portugal departs from Falcone-Borsellino International Airport on Sat, Mar 8, arriving at São Tomé International Airport. One-way Prices start from €847 including taxes and charges.

      • PMO12:20
        30h 35m
        2 stops
        TMS17:55
        Sat, Mar 8|Palermo - Sao Tome Island|Lufthansa
        €937
        €937

        Choose Lufthansa flights from Palermo to Sao Tome Island. The one-way connecting flight with Lufthansa departs from Falcone-Borsellino International Airport on Sat, Mar 8, arriving at São Tomé International Airport. One-way Prices start from €937 including taxes and charges.

      • PMO10:05
        32h 50m
        2 stops
        TMS17:55
        Sat, Mar 8|Palermo - Sao Tome Island|ITA Airways
        €943
        €943

        Choose ITA Airways flights from Palermo to Sao Tome Island. The one-way connecting flight with ITA Airways departs from Falcone-Borsellino International Airport on Sat, Mar 8, arriving at São Tomé International Airport. One-way Prices start from €943 including taxes and charges.

      • PMO19:40
        23h 15m
        2 stops
        TMS17:55
        Sat, Mar 8|Palermo - Sao Tome Island|Aeroitalia Airlines
        €986
        €986

        Choose Aeroitalia Airlines flights from Palermo to Sao Tome Island. The one-way connecting flight with Aeroitalia Airlines departs from Falcone-Borsellino International Airport on Sat, Mar 8, arriving at São Tomé International Airport. One-way Prices start from €986 including taxes and charges.

      • PMO19:40
        23h 15m
        2 stops
        TMS17:55
        Sat, Mar 1|Palermo - Sao Tome Island|Aeroitalia Airlines
        €990
        €990

        Choose Aeroitalia Airlines flights from Palermo to Sao Tome Island. The one-way connecting flight with Aeroitalia Airlines departs from Falcone-Borsellino International Airport on Sat, Mar 1, arriving at São Tomé International Airport. One-way Prices start from €990 including taxes and charges.

      • PMO22:45
        20h 10m
        2 stops
        TMS17:55
        Sat, Mar 1|Palermo - Sao Tome Island|easyJet
        €995
        €995

        Choose easyJet flights from Palermo to Sao Tome Island. The one-way connecting flight with easyJet departs from Falcone-Borsellino International Airport on Sat, Mar 1, arriving at São Tomé International Airport. One-way Prices start from €995 including taxes and charges.

      • PMO09:20
        33h 35m
        2 stops
        TMS17:55
        Sat, Mar 8|Palermo - Sao Tome Island|easyJet
        €1,001
        €1,001

        Choose easyJet flights from Palermo to Sao Tome Island. The one-way connecting flight with easyJet departs from Falcone-Borsellino International Airport on Sat, Mar 8, arriving at São Tomé International Airport. One-way Prices start from €1,001 including taxes and charges.

      • PMO01:00 pm
        3h 5m
        Nonstop
        TMS02:00 pm
        Sun, Feb 23|Palermo - Sao Tome Island|TAP Air Portugal
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Palermo to Sao Tome Island flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. TO3813

    Transavia France

    11:30

    PMO

    2.6h

    14:05

    ORY

    --T--F-
    Search

  2. TP441

    TAP Air Portugal

    06:00

    ORY

    2.6h

    07:35

    LIS

    SMTWTFS

  3. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.7h

    17:35

    TMS

    --T-T-S

  4. TP7281

    TAP Air Portugal

    12:15

    PMO

    1.2h

    13:25

    FCO

    SMTWTFS
    Search

  5. TP839

    TAP Air Portugal

    05:55

    FCO

    3.2h

    08:05

    LIS

    SMTWTFS

  6. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.7h

    17:35

    TMS

    --T-T-S

  7. AZ1784

    ITA Airways

    12:40

    PMO

    1.2h

    13:50

    FCO

    SMTWTFS
    Search

  8. TP837

    TAP Air Portugal

    20:00

    FCO

    3.2h

    22:10

    LIS

    SMTWTFS

  9. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.7h

    17:35

    TMS

    --T-T-S

  10. LX1743

    Swiss Airlines

    14:50

    PMO

    2.0h

    16:50

    ZRH

    S--W--S
    Search

  11. TP935

    TAP Air Portugal

    06:10

    ZRH

    3.0h

    08:10

    LIS

    SMTWTFS

  12. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.7h

    17:35

    TMS

    --T-T-S

  13. LX1743

    Swiss Airlines

    14:50

    PMO

    2.0h

    16:50

    ZRH

    S--W--S
    Search

  14. TP933

    TAP Air Portugal

    18:00

    ZRH

    2.9h

    19:55

    LIS

    S-TWTFS

  15. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.7h

    17:35

    TMS

    --T-T-S

  16. AZ1792

    ITA Airways

    15:15

    PMO

    1.2h

    16:25

    FCO

    SMTWTFS
    Search

  17. TP837

    TAP Air Portugal

    20:00

    FCO

    3.2h

    22:10

    LIS

    SMTWTFS

  18. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.7h

    17:35

    TMS

    --T-T-S

  19. LH339

    Lufthansa

    17:55

    PMO

    2.4h

    20:20

    FRA

    ---W-F-
    Search

  20. TP575

    TAP Air Portugal

    06:05

    FRA

    3.3h

    08:20

    LIS

    SMTWTFS

  21. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.7h

    17:35

    TMS

    --T-T-S

  22. AZ1796

    ITA Airways

    19:25

    PMO

    1.6h

    21:00

    LIN

    SM-WTFS
    Search

  23. TP829

    TAP Air Portugal

    05:55

    MXP

    2.9h

    07:50

    LIS

    SMTWTFS

  24. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.7h

    17:35

    TMS

    --T-T-S

  25. XZ2716

    Aeroitalia Airlines

    20:05

    PMO

    1.2h

    21:15

    FCO

    SMTWTFS
    Search

  26. TP839

    TAP Air Portugal

    05:55

    FCO

    3.2h

    08:05

    LIS

    SMTWTFS

  27. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.7h

    17:35

    TMS

    --T-T-S

  28. U23510

    easyJet

    22:25

    PMO

    1.7h

    00:05

    MXP

    SMTWTFS
    Search

  29. TP829

    TAP Air Portugal

    05:55

    MXP

    2.9h

    07:50

    LIS

    SMTWTFS

  30. TP1527

    TAP Air Portugal

    09:55

    LIS

    8.7h

    17:35

    TMS

    --T-T-S
Find more flights and airlines

When is the cheapest time to fly from Palermo to Sao Tome Island?

These price trend charts carefully monitor and predict how flight prices from Palermo to Sao Tome Island will change. Keep a close eye on them to understand when the best time to buy your tickets is.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Palermo (PMO) to Sao Tome Island (TMS) the cheapest?

    Airlines adjust prices for flights from Palermo to Sao Tome Island based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Palermo (PMO) to Sao Tome Island (TMS) cost?

    According to Trip.com's data, the lowest price is around €2,637.

  • What is the transportation method from the main airport to downtown in Sao Tome Island?

    • The distance from São Tomé International Airport to downtown is about 5 km, by taxi about 20 minutes.

  • How many airports are there in Sao Tome Island (TMS)?

    There are 1 airport(s) near Sao Tome Island (TMS): São Tomé International Airport.

How to find a cheap flight from Palermo to Sao Tome Island

Understanding the common pitfalls when booking your flight tickets can help you save massively when it comes time to fly. We’ve listed our six essential steps to keep in mind when you’re booking flight tickets to help you find the best price.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | Palermo to Sao Tome Island

Off-season for travelMarch
Peak season for travelJune
Flight distance4,254.06 km
Popular airlineITA Airways

Contact Us

About

Other Services

Payment Methods
Our Partners
Copyright © 2025 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.