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Flights from Panama City to Des Moines
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Cheap flight deals from Panama City to Des Moines Starting at €279

Whether you’re going for a one-way or round-trip to Des Moines, we’ve got you covered! Check out these different flight options from Panama City below.

  • One way
  • Round-trip
      • PTY16:40
        22h 31m
        1 stop
        DSM14:11
        Tue, Mar 4|Panama City - Des Moines|United Airlines
        €279€376
        26% OFF
        26% OFF
        €376€279

        Choose United Airlines flights from Panama City to Des Moines. The one-way connecting flight with United Airlines departs from Tocumen International Airport on Tue, Mar 4, arriving at Des Moines International Airport. One-way Prices start from €279 including taxes and charges.

      • PTY01:00 pm
        3h 5m
        Nonstop
        DSM02:00 pm
        Fri, Feb 28|Panama City - Des Moines|United Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Panama City to Des Moines flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. UA1249

    United Airlines

    07:55

    PTY

    4.5h

    12:25

    IAH

    SMTWTFS
    Search

  2. UA1780

    United Airlines

    20:17

    IAH

    2.5h

    22:45

    DSM

    SMTWTFS

  3. UA1031

    United Airlines

    10:00

    PTY

    4.4h

    14:26

    IAH

    SMTWTFS
    Search

  4. UA1780

    United Airlines

    20:17

    IAH

    2.5h

    22:45

    DSM

    SMTWTFS

  5. AA960

    American Airlines

    13:20

    PTY

    3.1h

    17:25

    MIA

    SMTWTFS
    Search

  6. AA581

    American Airlines

    06:35

    MIA

    3.5h

    09:02

    ORD

    SMTWTFS

  7. AA6081

    American Airlines

    10:11

    ORD

    1.3h

    11:30

    DSM

    SMTWTFS

  8. DL1758

    Delta Air Lines

    14:02

    PTY

    4.3h

    19:20

    ATL

    SMTWTFS
    Search

  9. DL2668

    Delta Air Lines

    07:25

    ATL

    2.7h

    09:09

    MSP

    SMTWTFS

  10. DL4998

    Delta Air Lines

    09:00

    MSP

    1.2h

    10:11

    DSM

    SMTWTFS

  11. UA1033

    United Airlines

    15:20

    PTY

    4.3h

    19:41

    IAH

    SMTWTFS
    Search

  12. UA6166

    United Airlines

    12:10

    IAH

    2.5h

    14:39

    DSM

    SMTWTFS
Find more flights and airlines

When is the cheapest time to fly from Panama City to Des Moines?

Price trend charts are a great way of tracking how much your flights cost in the lead up to departure and can help you choose when to book your tickets. See how prices to Des Moines from Panama City have changed and are set to move below.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Panama City (PTY) to Des Moines (DSM) the cheapest?

    Airlines adjust prices for flights from Panama City to Des Moines based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Panama City (PTY) to Des Moines (DSM) cost?

    According to Trip.com's data, the lowest price is around €2,296.

  • How many airports are there in Des Moines (DSM)?

    There are 1 airport(s) near Des Moines (DSM): Des Moines International Airport.

How to find a cheap flight from Panama City to Des Moines

Understanding the common pitfalls when booking your flight tickets can help you save massively when it comes time to fly. We’ve listed our six essential steps to keep in mind when you’re booking flight tickets to help you find the best price.
1
Being flexible with your dates to get the cheapest Panama City to Des Moines ticket.
Tap "Date" on flight search bar to scan through the calender for Panama City to Des Moines airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Tue, Mar 4 at €279 for one-way flights.
2
Compare cheap Panama City to Des Moines flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from Panama City to Des Moines. The cheapest airline operating is United Airlines.
3
Set up a Price Alert
By setting up a Price Alert for your Panama City to Des Moines route, you can easily track the price of your airline tickets from without manually checking every day.
4
Don't miss cheap Panama City to Des Moines flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights. If registering a free membership, you can receive more deals for your flights.
5
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
6
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com and search for cheap flight tickets from Panama City to Des Moines to get exclusive deals for you.

Flight Info | Panama City to Des Moines

Cheapest direct flight price€278
Off-season for travelFebruary
Peak season for travelDecember
Flight distance3,877.9 km
Popular airlineUnited Airlines

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