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Flights from Panama City to Santa Cruz

Cheap flight deals from Panama City to Santa Cruz Starting at AED 468

We've found these cheap flights for you. You can book one-way or round-trip flight tickets.

  • Round-trip
  • One way

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

When is the cheapest time to fly from Panama City to Santa Cruz?

We monitor flight fares to help you find the best deals effortlessly

Cheapest flights
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  • 23 30

  • Apr

    30 6
  • 6 13
  • 13 20
  • 20 27

  • May

    27 4
  • 4 11
  • 11 18
  • 18 25

  • Jun

    25 1
  • 1 8
  • 8 15
Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Panama City (PTY) to Santa Cruz (SRZ) the cheapest?

    Airlines adjust prices for flights from Panama City to Santa Cruz based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Panama City (PTY) to Santa Cruz (SRZ) cost?

    According to Trip.com's data, the lowest price is around AED 1,675.

  • How long does it take to fly from Panama City (PTY) to Santa Cruz (SRZ)?

    It takes about 4 hours 50 minutes to fly from Panama City (PTY) to Santa Cruz (SRZ).

  • What is the transportation method from the main airport to downtown in Santa Cruz?

    • The distance from Viru Viru International Airport to downtown is about 17 km, by taxi about 30 minutes.

  • What time does the latest flight from Panama City to Santa Cruz depart?

    The latest flight departs from Panama City (PTY) at 21:19 and arrives in Santa Cruz (VVI) at 03:19.

  • What are the most popular airlines that fly from Panama City (PTY) to Santa Cruz (SRZ)?

    Airlines with flights from Panama City (PTY) to Santa Cruz (SRZ): Boliviana De Aviación, Copa Airlines and United Airlines.

  • What's the most popular airline for non-stop flights from Panama City (PTY) to Santa Cruz (SRZ)?

    Copa Airlines operates 1 non-stop flights from Panama City (PTY) to Santa Cruz (SRZ).

  • How many airports are there in Santa Cruz (SRZ)?

    There are 1 airport(s) near Santa Cruz (SRZ): Viru Viru International Airport.

How to find a cheap flight from Panama City to Santa Cruz

Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Panama City to Santa Cruz. Book your flights at the right time and save more.
1
Being flexible with your dates to get the cheapest Panama City to Santa Cruz ticket.
Tap "Date" on flight search bar to scan through the calender for Panama City to Santa Cruz airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Mon, Mar 31 at AED 2402 for one-way flights.
2
Compare cheap Panama City to Santa Cruz flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from Panama City to Santa Cruz. The cheapest airline operating is Copa Airlines.
3
Set up a Price Alert
By setting up a Price Alert for your Panama City to Santa Cruz route, you can easily track the price of your airline tickets from without manually checking every day.
4
Don't miss cheap Panama City to Santa Cruz flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights. If registering a free membership, you can receive more deals for your flights.
5
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
6
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com and search for cheap flight tickets from Panama City to Santa Cruz to get exclusive deals for you.

Flight Info | Panama City to Santa Cruz

Cheapest one-way flight price AED 467
Cheapest return ticket price AED 1,426
Off-season for travel March
Peak season for travel May
Flight distance 3,476.98 km
Average flight time 4 hours 50 minutes
Popular airline avianca

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