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Flights from Panama City to Santo Domingo
Cheap flight deals from Panama City to Santo Domingo Starting at AED 593
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
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Round-trip
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One way
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Cheapest nonstopPTY 12:522h 32mNonstopSDQ 16:24Panama City - Santo Domingo | Sat, Apr 26 | Copa AirlinesSDQ 11:512h 38mNonstopPTY 13:29Santo Domingo - Panama City | Tue, Apr 29 | Copa AirlinesAED 1,315 AED 1,64820% OFF20% OFFAED 1,648 AED 1,315
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PTY 09:372h 33mNonstopSDQ 13:10Panama City - Santo Domingo | Mon, May 19 | Copa AirlinesSDQ 17:372h 37mNonstopPTY 19:14Santo Domingo - Panama City | Mon, May 19 | Copa AirlinesAED 1,318 AED 1,64820% OFF20% OFFAED 1,648 AED 1,318
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PTY 17:2516h 25m1 stopsSDQ 10:50Panama City - Santo Domingo | Wed, Apr 2 | aviancaSDQ 18:107h1 stopsPTY 00:10Santo Domingo - Panama City | Wed, Apr 9 | aviancaAED 1,079 AED 1,64835% OFF35% OFFAED 1,648 AED 1,079
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PTY 22:0518h 10m1 stopsSDQ 17:15Panama City - Santo Domingo | Thu, Apr 24 | aviancaSDQ 11:4510h 25m1 stopsPTY 21:10Santo Domingo - Panama City | Tue, Apr 29 | aviancaAED 1,08034% OFFAED 1,648 AED 1,080
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PTY 09:506h 25m1 stopsSDQ 17:15Panama City - Santo Domingo | Thu, Apr 3 | aviancaSDQ 18:107h1 stopsPTY 00:10Santo Domingo - Panama City | Sun, Apr 6 | aviancaAED 1,08034% OFFAED 1,648 AED 1,080
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PTY 21:5512h1 stopsSDQ 10:55Panama City - Santo Domingo | Wed, Mar 26 | aviancaSDQ 18:107h1 stopsPTY 00:10Santo Domingo - Panama City | Wed, Apr 2 | aviancaAED 1,08134% OFFAED 1,648 AED 1,081
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PTY 22:0518h 10m1 stopsSDQ 17:15Panama City - Santo Domingo | Fri, Apr 4 | aviancaSDQ 11:455h 45m1 stopsPTY 16:30Santo Domingo - Panama City | Tue, Apr 8 | aviancaAED 1,08334% OFFAED 1,648 AED 1,083
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PTY 03:206h 30m1 stopsSDQ 10:50Panama City - Santo Domingo | Mon, Mar 31 | aviancaSDQ 11:455h 45m1 stopsPTY 16:30Santo Domingo - Panama City | Sat, Apr 5 | aviancaAED 1,08334% OFFAED 1,648 AED 1,083
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PTY 03:2512h 50m1 stopsSDQ 17:15Panama City - Santo Domingo | Tue, Apr 1 | aviancaSDQ 18:107h1 stopsPTY 00:10Santo Domingo - Panama City | Sat, Apr 5 | aviancaAED 1,08334% OFFAED 1,648 AED 1,083
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PTY 03:2012h 55m1 stopsSDQ 17:15Panama City - Santo Domingo | Thu, May 8 | aviancaSDQ 18:107h1 stopsPTY 00:10Santo Domingo - Panama City | Wed, May 14 | aviancaAED 1,08334% OFFAED 1,648 AED 1,083
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PTY 17:2516h 25m1 stopsSDQ 10:50Panama City - Santo Domingo | Wed, May 14 | aviancaSDQ 11:455h 45m1 stopsPTY 16:30Santo Domingo - Panama City | Tue, May 20 | aviancaAED 1,08434% OFFAED 1,648 AED 1,084
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PTY 03:196h 36m1 stopsSDQ 10:55Panama City - Santo Domingo | Tue, Mar 25 | aviancaSDQ 11:5010h 10m1 stopsPTY 21:00Santo Domingo - Panama City | Thu, Mar 27 | aviancaAED 1,08534% OFFAED 1,648 AED 1,085
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PTY 13:0017h 25m1 stopsSDQ Invalid DatePanama City - Santo Domingo | Thu, Mar 27 | Normal AirlineSDQ 15:006hNonstopPTY 16:00Santo Domingo - Panama City | Sat, Mar 29 | Normal AirlineFind More FlightsFind More Flights
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Cheapest nonstopPTY 09:372h 32mNonstopSDQ 13:09Panama City - Santo Domingo | Sat, Apr 19 | Copa AirlinesAED 1,674 AED 2,10520% OFF20% OFFAED 2,105 AED 1,674
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PTY 23:132h 27mNonstopSDQ 02:40Panama City - Santo Domingo | Sat, Apr 26 | Copa AirlinesAED 1,684 AED 2,10520% OFF20% OFFAED 2,105 AED 1,684
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PTY 03:256h 25m1 stopsSDQ 10:50Panama City - Santo Domingo | Sat, Apr 5 | aviancaAED 593 AED 2,10572% OFF72% OFFAED 2,105 AED 593
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PTY 03:2012h 55m1 stopsSDQ 17:15Panama City - Santo Domingo | Fri, Apr 4 | aviancaAED 61471% OFFAED 2,105 AED 614
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PTY 22:0511h 45m1 stopsSDQ 10:50Panama City - Santo Domingo | Mon, May 12 | aviancaAED 61471% OFFAED 2,105 AED 614
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PTY 03:2012h 55m1 stopsSDQ 17:15Panama City - Santo Domingo | Wed, Apr 2 | aviancaAED 61571% OFFAED 2,105 AED 615
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PTY 22:0511h 45m1 stopsSDQ 10:50Panama City - Santo Domingo | Sun, Mar 30 | aviancaAED 61571% OFFAED 2,105 AED 615
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PTY 03:1913h 1m1 stopsSDQ 17:20Panama City - Santo Domingo | Fri, Mar 28 | aviancaAED 61571% OFFAED 2,105 AED 615
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PTY 17:2516h 25m1 stopsSDQ 10:50Panama City - Santo Domingo | Mon, Mar 31 | aviancaAED 61571% OFFAED 2,105 AED 615
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PTY 22:0518h 10m1 stopsSDQ 17:15Panama City - Santo Domingo | Thu, May 8 | aviancaAED 61771% OFFAED 2,105 AED 617
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PTY 11:055h 10m1 stopsSDQ 17:15Panama City - Santo Domingo | Wed, Apr 9 | aviancaAED 61771% OFFAED 2,105 AED 617
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PTY 03:196h 36m1 stopsSDQ 10:55Panama City - Santo Domingo | Tue, Mar 25 | aviancaAED 61871% OFFAED 2,105 AED 618
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PTY 13:0017h 25m1 stopsSDQ Invalid DatePanama City - Santo Domingo | Thu, Mar 27 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
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Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Frequently Asked Questions
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When are flight tickets from Panama City (PTY) to Santo Domingo (SDQ) the cheapest?
Airlines adjust prices for flights from Panama City to Santo Domingo based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much do flights from Panama City (PTY) to Santo Domingo (SDQ) cost?
According to Trip.com's data, the lowest price is around AED 1,996. -
How long does it take to fly from Panama City (PTY) to Santo Domingo (SDQ)?
It takes about 2 hours 32 minutes to fly from Panama City (PTY) to Santo Domingo (SDQ). -
What is the transportation method from the main airport to downtown in Santo Domingo?
- The distance from Las Américas International Airport to downtown is about 33 km, by taxi about 50 minutes.
- The distance from La Isabela International Airport to downtown is about 8 km, by taxi about 20 minutes.
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What are the most popular airlines that fly from Panama City (PTY) to Santo Domingo (SDQ)?
Airlines with flights from Panama City (PTY) to Santo Domingo (SDQ): Copa Airlines, Turkish Airlines, KLM and Air France. -
What's the most popular airline for non-stop flights from Panama City (PTY) to Santo Domingo (SDQ)?
Copa Airlines operates 1 non-stop flights from Panama City (PTY) to Santo Domingo (SDQ). -
How many airports are there in Santo Domingo (SDQ)?
There are 2 airport(s) near Santo Domingo (SDQ): La Isabela International Airport and Las Américas International Airport.
How to find a cheap flight from Panama City to Santo Domingo
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Panama City to Santo Domingo. Book your flights at the right time and save more.
Being flexible with your dates to get the cheapest Panama City to Santo Domingo ticket.
Tap "Date" on flight search bar to scan through the calender for Panama City to Santo Domingo airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Sat, Apr 19 at AED 1674 for one-way flights.
Compare cheap Panama City to Santo Domingo flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from Panama City to Santo Domingo. The cheapest airline operating is Copa Airlines.
Set up a Price Alert
By setting up a Price Alert for your Panama City to Santo Domingo route, you can easily track the price of your airline tickets from without manually checking every day.
Don't miss cheap Panama City to Santo Domingo flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights. If registering a free membership, you can receive more deals for your flights.
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com and search for cheap flight tickets from Panama City to Santo Domingo to get exclusive deals for you.
Flight Info | Panama City to Santo Domingo
Cheapest one-way flight price | AED 593 |
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Cheapest return ticket price | AED 1,314 |
Off-season for travel | March |
Peak season for travel | December |
Flight distance | 1,481.79 km |
Average flight time | 2 hours 32 minutes |
Popular airline | avianca |
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