Cheap Flights from San Francisco to Mytilene
Search for flights from San Francisco to Mytilene and find the best flight deals today!
Swipe up to view more
>>>>>
Flights from San Francisco to Mytilene
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Convenient & reliable booking and payment system
San Francisco to Mytilene | Find Cheap Flight Deals
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
- One way
- Round-trip
SFO01:00 pm3h 5mNonstopMJT02:00 pmSat, Feb 22|San Francisco - Mytilene|Normal AirlineSearch FlightsSearch Flights
Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
When is the cheapest time to fly from San Francisco to Mytilene?
Explore the best time to buy affordable tickets to Mytilene with our price trend chart, which predicts how flight prices will change in the coming weeks from previous data.
Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Frequently Asked Questions
How to find a cheap flight from San Francisco to Mytilene
If you don’t know some of the key things to look out for when buying flight tickets, prices can often end up sky high or, worse, sold out!
We’ve carefully compiled our six most important steps to help ensure you’re getting the best deals when planning your next journey.
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
Compare Flight Prices
Compare prices on travel agency and airline websites.
Look Out for Deals
Check airline and travel agency websites for latest flight deals
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com
Flight Info | San Francisco to Mytilene
| Off-season for travel | January |
|---|---|
| Peak season for travel | June |
| Flight distance | 10,919.35 km |
More Travel Options
Top Flight From San Francisco
- San Francisco to Harrisburg Flights
- San Francisco to Joensuu Flights
- San Francisco to Batumi Flights
- San Francisco to Butuan Flights
- San Francisco to Simferopol Flights
- San Francisco to Abu Dhabi Flights
- San Francisco to Dubai Flights
- San Francisco to Lake Havasu City Flights
- San Francisco to Cajamarca Flights
- San Francisco to Novosibirsk Flights
- San Francisco to Iguazu Flights
- San Francisco to Bhopal Flights
- San Francisco to Innsbruck Flights
- San Francisco to Mersin Flights
- San Francisco to Caxias Do Sul Flights
- San Francisco to Amman Flights
- San Francisco to Massena Flights
- San Francisco to Badajoz Flights
- San Francisco to Saint Martin Flights
- San Francisco to Setif Flights
Top Flight to Mytilene
- Bergen to Mytilene Flights
- Klagenfurt to Mytilene Flights
- Frankfurt to Mytilene Flights
- Ikaria Island to Mytilene Flights
- Birmingham to Mytilene Flights
- Bridgetown to Mytilene Flights
- Alghero to Mytilene Flights
- Innsbruck to Mytilene Flights
- Kahramanmaras to Mytilene Flights
- Islamabad to Mytilene Flights
- Lille to Mytilene Flights
- Kithira to Mytilene Flights
- Dublin to Mytilene Flights
- Antwerp to Mytilene Flights
- Angelholm to Mytilene Flights
More Flight Options
Payment Methods
Our Partners
Copyright © 2025 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.
Site Operator: Trip.com Travel Singapore Pte. Ltd.