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Flights from San Francisco to Santiago
Cheap flight deals from San Francisco to Santiago Starting at AED 1,132
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
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Round-trip
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One way
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SFO 01:4022h 7m1 stopsSCL 02:47San Francisco - Santiago | Fri, Apr 25 | Copa AirlinesSCL 04:1117h 12m1 stopsSFO 18:23Santiago - San Francisco | Fri, May 2 | Copa AirlinesAED 2,354 AED 3,25028% OFF28% OFFAED 3,250 AED 2,354
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SFO 01:4022h 7m1 stopsSCL 02:47San Francisco - Santiago | Fri, Apr 11 | Copa AirlinesSCL 04:1717h 13m1 stopsSFO 18:30Santiago - San Francisco | Tue, Apr 15 | Copa AirlinesAED 2,358 AED 3,25027% OFF27% OFFAED 3,250 AED 2,358
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SFO 01:4622h 1m1 stopsSCL 03:47San Francisco - Santiago | Mon, Mar 31 | Copa AirlinesSCL 03:3019h1 stopsSFO 18:30Santiago - San Francisco | Thu, Apr 3 | Copa AirlinesAED 2,371 AED 3,25027% OFF27% OFFAED 3,250 AED 2,371
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SFO 01:4024h 24m1 stopsSCL 05:04San Francisco - Santiago | Sat, Apr 12 | Copa AirlinesSCL 00:1926h 21m1 stopsSFO 23:40Santiago - San Francisco | Wed, Apr 16 | Copa AirlinesAED 2,38227% OFFAED 3,250 AED 2,382
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SFO 01:4018h 31m1 stopsSCL 00:11San Francisco - Santiago | Wed, Apr 2 | Copa AirlinesSCL 05:1722h 23m1 stopsSFO 23:40Santiago - San Francisco | Fri, Apr 4 | Copa AirlinesAED 2,39426% OFFAED 3,250 AED 2,394
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SFO 01:4018h 4m1 stopsSCL 22:44San Francisco - Santiago | Mon, Apr 7 | Copa AirlinesSCL 02:3024h 10m1 stopsSFO 23:40Santiago - San Francisco | Mon, Apr 14 | Copa AirlinesAED 2,40426% OFFAED 3,250 AED 2,404
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SFO 06:1020h 40m1 stopsSCL 05:50San Francisco - Santiago | Fri, May 2 | Delta Air LinesSCL 20:4023h 53m1 stopsSFO 17:33Santiago - San Francisco | Tue, May 6 | Delta Air LinesAED 2,40726% OFFAED 3,250 AED 2,407
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SFO 01:4618h 3m1 stopsSCL 23:49San Francisco - Santiago | Sun, Mar 30 | Copa AirlinesSCL 03:3024h 10m1 stopsSFO 23:40Santiago - San Francisco | Fri, Apr 4 | Copa AirlinesAED 2,41326% OFFAED 3,250 AED 2,413
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SFO 01:3722h 10m1 stopsSCL 02:47San Francisco - Santiago | Mon, May 5 | Copa AirlinesSCL 04:1117h 12m1 stopsSFO 18:23Santiago - San Francisco | Fri, May 9 | Copa AirlinesAED 2,43425% OFFAED 3,250 AED 2,434
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SFO 11:1215h 38m1 stopsSCL 05:50San Francisco - Santiago | Wed, May 14 | Delta Air LinesSCL 20:4018h 5m1 stopsSFO 11:45Santiago - San Francisco | Wed, May 21 | Delta Air LinesAED 2,43725% OFFAED 3,250 AED 2,437
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SFO 13:0017h 25m1 stopsSCL Invalid DateSan Francisco - Santiago | Sat, Mar 22 | Normal AirlineSCL 15:006hNonstopSFO 16:00Santiago - San Francisco | Mon, Mar 24 | Normal AirlineFind More FlightsFind More Flights
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SFO 01:4614h 34m1 stopsSCL 20:20San Francisco - Santiago | Sun, Mar 30 | Copa AirlinesAED 1,132 AED 1,55727% OFF27% OFFAED 1,557 AED 1,132
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SFO 01:3714h 47m1 stopsSCL 19:24San Francisco - Santiago | Mon, May 12 | Copa AirlinesAED 1,132 AED 1,55727% OFF27% OFFAED 1,557 AED 1,132
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SFO 19:5220h 32m1 stopsSCL 19:24San Francisco - Santiago | Tue, May 13 | Copa AirlinesAED 1,132 AED 1,55727% OFF27% OFFAED 1,557 AED 1,132
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SFO 01:4018h 4m1 stopsSCL 23:44San Francisco - Santiago | Tue, Apr 1 | Copa AirlinesAED 1,13327% OFFAED 1,557 AED 1,133
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SFO 01:4022h 7m1 stopsSCL 03:47San Francisco - Santiago | Wed, Apr 2 | Copa AirlinesAED 1,13427% OFFAED 1,557 AED 1,134
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SFO 01:4014h 44m1 stopsSCL 19:24San Francisco - Santiago | Wed, Apr 16 | Copa AirlinesAED 1,13427% OFFAED 1,557 AED 1,134
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SFO 01:4024h 24m1 stopsSCL 05:04San Francisco - Santiago | Sat, Apr 26 | Copa AirlinesAED 1,13627% OFFAED 1,557 AED 1,136
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SFO 01:4024h 24m1 stopsSCL 06:04San Francisco - Santiago | Fri, Apr 4 | Copa AirlinesAED 1,15726% OFFAED 1,557 AED 1,157
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SFO 01:4022h 7m1 stopsSCL 02:47San Francisco - Santiago | Fri, Apr 11 | Copa AirlinesAED 1,15926% OFFAED 1,557 AED 1,159
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SFO 01:3714h 47m1 stopsSCL 19:24San Francisco - Santiago | Mon, May 5 | Copa AirlinesAED 1,16825% OFFAED 1,557 AED 1,168
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SFO 13:0017h 25m1 stopsSCL Invalid DateSan Francisco - Santiago | Sat, Mar 22 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
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Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Frequently Asked Questions
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When are flight tickets from San Francisco (SFO) to Santiago (SCL) the cheapest?
Airlines adjust prices for flights from San Francisco to Santiago based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much do flights from San Francisco (SFO) to Santiago (SCL) cost?
According to Trip.com's data, the lowest price is around AED 3,022. -
What is the transportation method from the main airport to downtown in Santiago?
- The distance from Arturo Merino Benitez Airport to downtown is about 12 km, by taxi about 30 minutes.
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How many airports are there in Santiago (SCL)?
There are 1 airport(s) near Santiago (SCL): Arturo Merino Benitez Airport.
How to find a cheap flight from San Francisco to Santiago
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from San Francisco to Santiago. Book your flights at the right time and save more.
Being flexible with your dates to get the cheapest San Francisco to Santiago ticket.
Tap "Date" on flight search bar to scan through the calender for San Francisco to Santiago airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Sun, Mar 30 at AED 1132 for one-way flights.
Compare cheap San Francisco to Santiago flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from San Francisco to Santiago. The cheapest airline operating is Copa Airlines.
Set up a Price Alert
By setting up a Price Alert for your San Francisco to Santiago route, you can easily track the price of your airline tickets from without manually checking every day.
Don't miss cheap San Francisco to Santiago flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights. If registering a free membership, you can receive more deals for your flights.
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com and search for cheap flight tickets from San Francisco to Santiago to get exclusive deals for you.
Flight Info | San Francisco to Santiago
Cheapest one-way flight price | AED 1,121 |
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Off-season for travel | April |
Peak season for travel | December |
Flight distance | 9,530.72 km |
Popular airline | Aeromexico |
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