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Flights from Santa Ana to Knoxville
Cheap flight deals from Santa Ana to Knoxville
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
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Round-trip
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One way
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SNA 10:256h 28m1 stopsTYS 19:53Santa Ana - Knoxville | Wed, May 7 | American AirlinesTYS 05:208h 21m1 stopsSNA 10:41Knoxville - Santa Ana | Wed, May 14 | American AirlinesAED 841 AED 1,49144% OFF44% OFFAED 1,491 AED 841
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SNA 14:156h 36m1 stopsTYS 23:51Santa Ana - Knoxville | Wed, May 7 | Delta Air LinesTYS 05:458h 25m1 stopsSNA 11:10Knoxville - Santa Ana | Wed, May 14 | Delta Air LinesAED 939 AED 1,49137% OFF37% OFFAED 1,491 AED 939
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SNA 12:178h 34m1 stopsTYS 23:51Santa Ana - Knoxville | Tue, May 27 | Delta Air LinesTYS 05:458h 22m1 stopsSNA 11:07Knoxville - Santa Ana | Tue, Jun 3 | Delta Air LinesAED 1,005 AED 1,49133% OFF33% OFFAED 1,491 AED 1,005
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SNA 14:156h 36m1 stopsTYS 23:51Santa Ana - Knoxville | Sun, May 25 | Delta Air LinesTYS 05:458h 25m1 stopsSNA 11:10Knoxville - Santa Ana | Wed, May 28 | Delta Air LinesAED 1,08427% OFFAED 1,491 AED 1,084
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SNA 14:156h 36m1 stopsTYS 23:51Santa Ana - Knoxville | Sat, May 24 | Delta Air LinesTYS 05:458h 25m1 stopsSNA 11:10Knoxville - Santa Ana | Wed, May 28 | Delta Air LinesAED 1,08727% OFFAED 1,491 AED 1,087
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SNA 10:359h 5m1 stopsTYS 22:40Santa Ana - Knoxville | Sun, May 25 | United AirlinesTYS 17:157h 45m1 stopsSNA 22:00Knoxville - Santa Ana | Wed, May 28 | United AirlinesAED 1,11825% OFFAED 1,491 AED 1,118
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SNA 10:359h 30m1 stopsTYS 23:05Santa Ana - Knoxville | Sat, May 24 | United AirlinesTYS 16:528h 20m1 stopsSNA 22:12Knoxville - Santa Ana | Wed, May 28 | United AirlinesAED 1,12125% OFFAED 1,491 AED 1,121
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SNA 08:208h 46m1 stopsTYS 20:06Santa Ana - Knoxville | Sat, May 3 | United AirlinesTYS 16:147h 41m1 stopsSNA 20:55Knoxville - Santa Ana | Tue, May 6 | United AirlinesAED 1,14623% OFFAED 1,491 AED 1,146
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SNA 12:318h 27m1 stopsTYS 23:58Santa Ana - Knoxville | Fri, May 9 | American AirlinesTYS 16:107h 40m1 stopsSNA 20:50Knoxville - Santa Ana | Fri, May 16 | American AirlinesAED 1,15323% OFFAED 1,491 AED 1,153
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SNA 14:156h 36m1 stopsTYS 23:51Santa Ana - Knoxville | Fri, May 9 | Delta Air LinesTYS 16:228h 53m1 stopsSNA 22:15Knoxville - Santa Ana | Fri, May 16 | Delta Air LinesAED 1,19320% OFFAED 1,491 AED 1,193
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SNA 13:0017h 25m1 stopsTYS Invalid DateSanta Ana - Knoxville | Mon, Apr 28 | Normal AirlineTYS 15:006hNonstopSNA 16:00Knoxville - Santa Ana | Wed, Apr 30 | Normal AirlineFind More FlightsFind More Flights
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SNA 12:0125h 28m1 stopsTYS 16:29Santa Ana - Knoxville | Wed, Jun 11 | Frontier AirlinesAED 410 AED 70842% OFF42% OFFAED 708 AED 410
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SNA 14:156h 36m1 stopsTYS 23:51Santa Ana - Knoxville | Tue, May 20 | Delta Air LinesAED 495 AED 70830% OFF30% OFFAED 708 AED 495
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SNA 14:156h 36m1 stopsTYS 23:51Santa Ana - Knoxville | Sat, May 24 | Delta Air LinesAED 495 AED 70830% OFF30% OFFAED 708 AED 495
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SNA 11:469h 5m1 stopsTYS 23:51Santa Ana - Knoxville | Wed, May 28 | Delta Air LinesAED 50628% OFFAED 708 AED 506
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SNA 06:4512h 14m1 stopsTYS 21:59Santa Ana - Knoxville | Fri, May 9 | Spirit AirlinesAED 51927% OFFAED 708 AED 519
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SNA 12:457h 19m1 stopsTYS 23:04Santa Ana - Knoxville | Thu, May 29 | Delta Air LinesAED 53924% OFFAED 708 AED 539
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SNA 11:469h 5m1 stopsTYS 23:51Santa Ana - Knoxville | Fri, May 30 | Delta Air LinesAED 53924% OFFAED 708 AED 539
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SNA 14:156h 36m1 stopsTYS 23:51Santa Ana - Knoxville | Sun, May 25 | Delta Air LinesAED 54124% OFFAED 708 AED 541
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SNA 10:508h 55m1 stopsTYS 22:45Santa Ana - Knoxville | Wed, May 14 | United AirlinesAED 56021% OFFAED 708 AED 560
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SNA 08:206h 36m1 stopsTYS 17:56Santa Ana - Knoxville | Tue, May 20 | United AirlinesAED 56720% OFFAED 708 AED 567
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SNA 13:0017h 25m1 stopsTYS Invalid DateSanta Ana - Knoxville | Mon, Apr 28 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
Flight Info | Santa Ana to Knoxville
Cheapest one-way flight price | AED 410 |
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Off-season for travel | April |
Peak season for travel | January |
Flight distance | 3,088.82 km |
Popular airline | Delta Air Lines |
When is the cheapest time to fly from Santa Ana to Knoxville?
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Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Frequently Asked Questions
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When are flight tickets from Santa Ana (SNA) to Knoxville (TYS) the cheapest?
Airlines adjust prices for flights from Santa Ana to Knoxville based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much do flights from Santa Ana (SNA) to Knoxville (TYS) cost?
According to Trip.com's data, the lowest price is around AED 2,881. -
How many airports are there in Knoxville (TYS)?
There are 1 airport(s) near Knoxville (TYS): Mcghee Tyson Airport.
How to find a cheap flight from Santa Ana to Knoxville
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Santa Ana to Knoxville. Book your flights at the right time and save more.
Being flexible with your dates to get the cheapest Santa Ana to Knoxville ticket.
Tap "Date" on flight search bar to scan through the calender for Santa Ana to Knoxville airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Wed, Jun 11 at AED 410 for one-way flights.
Compare cheap Santa Ana to Knoxville flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from Santa Ana to Knoxville. The cheapest airline operating is Frontier Airlines.
Set up a Price Alert
By setting up a Price Alert for your Santa Ana to Knoxville route, you can easily track the price of your airline tickets from without manually checking every day.
Don't miss cheap Santa Ana to Knoxville flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights. If registering a free membership, you can receive more deals for your flights.
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com and search for cheap flight tickets from Santa Ana to Knoxville to get exclusive deals for you.
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