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Flights from Santiago to Guayaquil
Cheap flight deals from Santiago to Guayaquil Starting at AED 550
We've found these cheap flights for you. You can book one-way or round-trip flight tickets.
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One way
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Cheapest nonstopSCL 23:505h 23mNonstopGYE 04:13Santiago - Guayaquil | Wed, May 7 | LATAM AirlinesGYE 14:454h 53mNonstopSCL 20:38Guayaquil - Santiago | Wed, May 14 | LATAM AirlinesAED 1,189 AED 1,50221% OFF21% OFFAED 1,502 AED 1,189
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SCL 23:505h 23mNonstopGYE 04:13Santiago - Guayaquil | Wed, Apr 16 | LATAM AirlinesGYE 14:454h 53mNonstopSCL 20:38Guayaquil - Santiago | Wed, Apr 23 | LATAM AirlinesAED 1,275 AED 1,50215% OFF15% OFFAED 1,502 AED 1,275
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SCL 23:505h 23mNonstopGYE 04:13Santiago - Guayaquil | Fri, May 16 | LATAM AirlinesGYE 14:454h 53mNonstopSCL 20:38Guayaquil - Santiago | Wed, May 21 | LATAM AirlinesAED 1,295 AED 1,50214% OFF14% OFFAED 1,502 AED 1,295
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SCL 23:505h 23mNonstopGYE 04:13Santiago - Guayaquil | Sat, Apr 26 | LATAM AirlinesGYE 14:454h 53mNonstopSCL 20:38Guayaquil - Santiago | Sat, May 3 | LATAM AirlinesAED 1,29514% OFFAED 1,502 AED 1,295
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SCL 21:3517h 40m1 stopsGYE 14:15Santiago - Guayaquil | Sun, Apr 13 | LATAM AirlinesGYE 13:007h 55m1 stopsSCL 21:55Guayaquil - Santiago | Fri, Apr 18 | LATAM AirlinesAED 1,18821% OFFAED 1,502 AED 1,188
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SCL 07:158h1 stopsGYE 14:15Santiago - Guayaquil | Wed, Apr 30 | LATAM AirlinesGYE 14:454h 53mNonstopSCL 20:38Guayaquil - Santiago | Mon, May 5 | LATAM AirlinesAED 1,27015% OFFAED 1,502 AED 1,270
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SCL 20:4016h 35m1 stopsGYE 11:15Santiago - Guayaquil | Tue, Apr 1 | LATAM AirlinesGYE 20:407h 5m1 stopsSCL 04:45Guayaquil - Santiago | Sun, Apr 6 | LATAM AirlinesAED 1,32512% OFFAED 1,502 AED 1,325
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SCL 20:5016h 15m1 stopsGYE 11:05Santiago - Guayaquil | Tue, Mar 25 | LATAM AirlinesGYE 12:558h1 stopsSCL 22:55Guayaquil - Santiago | Wed, Apr 2 | LATAM AirlinesAED 1,34810% OFFAED 1,502 AED 1,348
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SCL 20:4016h 30m1 stopsGYE 11:10Santiago - Guayaquil | Wed, Apr 2 | LATAM AirlinesGYE 12:558h1 stopsSCL 22:55Guayaquil - Santiago | Sat, Apr 5 | LATAM AirlinesAED 1,3639% OFFAED 1,502 AED 1,363
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SCL 07:407h 35m1 stopsGYE 14:15Santiago - Guayaquil | Wed, Apr 9 | LATAM AirlinesGYE 12:508h 5m1 stopsSCL 21:55Guayaquil - Santiago | Wed, Apr 16 | LATAM AirlinesAED 1,3679% OFFAED 1,502 AED 1,367
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SCL 13:0017h 25m1 stopsGYE Invalid DateSantiago - Guayaquil | Mon, Mar 24 | Normal AirlineGYE 15:006hNonstopSCL 16:00Guayaquil - Santiago | Wed, Mar 26 | Normal AirlineFind More FlightsFind More Flights
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Cheapest nonstopSCL 23:505h 23mNonstopGYE 04:13Santiago - Guayaquil | Tue, Apr 22 | LATAM AirlinesAED 550 AED 68620% OFF20% OFFAED 686 AED 550
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SCL 23:505h 23mNonstopGYE 04:13Santiago - Guayaquil | Thu, May 1 | LATAM AirlinesAED 551 AED 68620% OFF20% OFFAED 686 AED 551
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SCL 00:455h 16mNonstopGYE 04:01Santiago - Guayaquil | Fri, Mar 28 | LATAM AirlinesAED 594 AED 68613% OFF13% OFFAED 686 AED 594
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SCL 23:505h 23mNonstopGYE 04:13Santiago - Guayaquil | Mon, Apr 21 | LATAM AirlinesAED 59513% OFFAED 686 AED 595
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SCL 23:505h 23mNonstopGYE 04:13Santiago - Guayaquil | Mon, May 19 | LATAM AirlinesAED 61910% OFFAED 686 AED 619
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SCL 05:359h 40m1 stopsGYE 14:15Santiago - Guayaquil | Mon, Apr 14 | LATAM AirlinesAED 59913% OFFAED 686 AED 599
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SCL 08:108h 5m1 stopsGYE 14:15Santiago - Guayaquil | Sat, Mar 22 | LATAM AirlinesAED 61011% OFFAED 686 AED 610
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SCL 07:058h 10m1 stopsGYE 14:15Santiago - Guayaquil | Sun, May 18 | LATAM AirlinesAED 61910% OFFAED 686 AED 619
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SCL 07:158h1 stopsGYE 14:15Santiago - Guayaquil | Wed, Apr 16 | LATAM AirlinesAED 6249% OFFAED 686 AED 624
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SCL 21:3514h 40m1 stopsGYE 11:15Santiago - Guayaquil | Fri, Apr 25 | LATAM AirlinesAED 6249% OFFAED 686 AED 624
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SCL 13:0017h 25m1 stopsGYE Invalid DateSantiago - Guayaquil | Mon, Mar 24 | Normal AirlineFind More FlightsFind More Flights
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Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.
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Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.
Frequently Asked Questions
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When are flight tickets from Santiago (SCL) to Guayaquil (GYE) the cheapest?
Airlines adjust prices for flights from Santiago to Guayaquil based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays. -
How much do flights from Santiago (SCL) to Guayaquil (GYE) cost?
According to Trip.com's data, the lowest price is around AED 1,259. -
How long does it take to fly from Santiago (SCL) to Guayaquil (GYE)?
It takes about 5 hours 23 minutes to fly from Santiago (SCL) to Guayaquil (GYE). -
What is the transportation method from the main airport to downtown in Guayaquil?
- The distance from Jose Joaquin De Olmedo International Airport to downtown is about 4 km, by taxi about 20 minutes.
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What are the most popular airlines that fly from Santiago (SCL) to Guayaquil (GYE)?
Airlines with flights from Santiago (SCL) to Guayaquil (GYE): LATAM Airlines. -
What's the most popular airline for non-stop flights from Santiago (SCL) to Guayaquil (GYE)?
LATAM Airlines operates 2 non-stop flights from Santiago (SCL) to Guayaquil (GYE). -
How many airports are there in Guayaquil (GYE)?
There are 1 airport(s) near Guayaquil (GYE): Jose Joaquin De Olmedo International Airport.
How to find a cheap flight from Santiago to Guayaquil
Wait until the last minute and flight costs are often sky-high. Plan ahead, book the right way, and your savings can soar. We have loads of saving tips to help you find a cheap flight from Santiago to Guayaquil. Book your flights at the right time and save more.
Being flexible with your dates to get the cheapest Santiago to Guayaquil ticket.
Tap "Date" on flight search bar to scan through the calender for Santiago to Guayaquil airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Tue, Apr 22 at AED 550 for one-way flights.
Compare cheap Santiago to Guayaquil flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from Santiago to Guayaquil. The cheapest airline operating is LATAM Airlines.
Set up a Price Alert
By setting up a Price Alert for your Santiago to Guayaquil route, you can easily track the price of your airline tickets from without manually checking every day.
Don't miss cheap Santiago to Guayaquil flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights. If registering a free membership, you can receive more deals for your flights.
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com and search for cheap flight tickets from Santiago to Guayaquil to get exclusive deals for you.
Flight Info | Santiago to Guayaquil
Cheapest one-way flight price | AED 550 |
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Cheapest return ticket price | AED 1,188 |
Off-season for travel | April |
Peak season for travel | December |
Flight distance | 3,600.11 km |
Average flight time | 5 hours 23 minutes |
Popular airline | avianca |
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