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Cheap flight deals from Santiago to Madrid Starting at €388

Discover our range of affordable one-way and round-trip flights from Santiago to Madrid and kick-start your next adventure today!

  • One way
  • Round-trip
      • Cheapest nonstop
        STI22:35
        8h 15m
        Nonstop
        MAD11:50
        Thu, Mar 6|Santiago - Madrid|Air Europa
        €560€677
        17% OFF
        17% OFF
        €677€560

        Choose Air Europa flights from Santiago to Madrid. The one-way direct flight with Air Europa departs from Cibao International Airport on Thu, Mar 6, arriving at Madrid Barajas Airport. One-way Prices start from €560 including taxes and charges.

      • STI22:35
        8h 15m
        Nonstop
        MAD11:50
        Sat, Feb 15|Santiago - Madrid|Air Europa
        €562€677
        17% OFF
        17% OFF
        €677€562

        Choose Air Europa flights from Santiago to Madrid. The one-way direct flight with Air Europa departs from Cibao International Airport on Sat, Feb 15, arriving at Madrid Barajas Airport. One-way Prices start from €562 including taxes and charges.

      • STI22:04
        28h 11m
        1 stop
        MAD08:15
        Tue, Apr 1|Santiago - Madrid|Jetblue Airways
        €388€677
        43% OFF
        43% OFF
        €677€388

        Choose Jetblue Airways flights from Santiago to Madrid. The one-way connecting flight with Jetblue Airways departs from Cibao International Airport on Tue, Apr 1, arriving at Madrid Barajas Airport. One-way Prices start from €388 including taxes and charges.

      • STI03:13
        20h 47m
        1 stop
        MAD06:00
        Wed, Apr 2|Santiago - Madrid|Jetblue Airways
        €388
        €388

        Choose Jetblue Airways flights from Santiago to Madrid. The one-way connecting flight with Jetblue Airways departs from Cibao International Airport on Wed, Apr 2, arriving at Madrid Barajas Airport. One-way Prices start from €388 including taxes and charges.

      • STI05:05
        21h 50m
        1 stop
        MAD07:55
        Wed, Feb 19|Santiago - Madrid|Jetblue Airways
        €403
        €403

        Choose Jetblue Airways flights from Santiago to Madrid. The one-way connecting flight with Jetblue Airways departs from Cibao International Airport on Wed, Feb 19, arriving at Madrid Barajas Airport. One-way Prices start from €403 including taxes and charges.

      • STI05:05
        20h
        1 stop
        MAD06:05
        Mon, Feb 17|Santiago - Madrid|Jetblue Airways
        €413
        €413

        Choose Jetblue Airways flights from Santiago to Madrid. The one-way connecting flight with Jetblue Airways departs from Cibao International Airport on Mon, Feb 17, arriving at Madrid Barajas Airport. One-way Prices start from €413 including taxes and charges.

      • STI17:30
        31h 35m
        1 stop
        MAD07:05
        Fri, Mar 28|Santiago - Madrid|Jetblue Airways
        €421
        €421

        Choose Jetblue Airways flights from Santiago to Madrid. The one-way connecting flight with Jetblue Airways departs from Cibao International Airport on Fri, Mar 28, arriving at Madrid Barajas Airport. One-way Prices start from €421 including taxes and charges.

      • STI18:30
        34h 45m
        1 stop
        MAD10:15
        Sat, Feb 15|Santiago - Madrid|Jetblue Airways
        €422
        €422

        Choose Jetblue Airways flights from Santiago to Madrid. The one-way connecting flight with Jetblue Airways departs from Cibao International Airport on Sat, Feb 15, arriving at Madrid Barajas Airport. One-way Prices start from €422 including taxes and charges.

      • STI05:05
        21h 50m
        1 stop
        MAD07:55
        Thu, Feb 20|Santiago - Madrid|Jetblue Airways
        €424
        €424

        Choose Jetblue Airways flights from Santiago to Madrid. The one-way connecting flight with Jetblue Airways departs from Cibao International Airport on Thu, Feb 20, arriving at Madrid Barajas Airport. One-way Prices start from €424 including taxes and charges.

      • STI06:00
        20h 55m
        1 stop
        MAD07:55
        Thu, Feb 27|Santiago - Madrid|United Airlines
        €431
        €431

        Choose United Airlines flights from Santiago to Madrid. The one-way connecting flight with United Airlines departs from Cibao International Airport on Thu, Feb 27, arriving at Madrid Barajas Airport. One-way Prices start from €431 including taxes and charges.

      • STI01:00 pm
        3h 5m
        Nonstop
        MAD02:00 pm
        Thu, Feb 20|Santiago - Madrid|Air Europa
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Santiago to Madrid flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. UA240

    United Airlines

    06:00

    STI

    4.0h

    10:02

    EWR

    SMTWTFS
    Search

  2. TP202

    TAP Air Portugal

    17:35

    EWR

    6.9h

    05:30

    LIS

    SMTWTF-

  3. TP1010

    TAP Air Portugal

    07:55

    LIS

    1.3h

    10:15

    MAD

    SMTWTFS

  4. UA240

    United Airlines

    06:00

    STI

    4.0h

    10:02

    EWR

    SMTWTFS
    Search

  5. AA8567

    American Airlines

    20:40

    JFK

    7.4h

    10:05

    MAD

    SMTWTFS

  6. UA240

    United Airlines

    06:00

    STI

    4.0h

    10:02

    EWR

    SMTWTFS
    Search

  7. AA094

    American Airlines

    19:05

    JFK

    7.2h

    08:15

    MAD

    SMTWTFS

  8. B6236

    Jetblue Airways

    06:15

    STI

    3.9h

    09:09

    JFK

    SMTWTFS
    Search

  9. UA051

    United Airlines

    19:25

    EWR

    7.6h

    09:00

    MAD

    SMTWTFS

  10. B6236

    Jetblue Airways

    06:15

    STI

    3.9h

    09:09

    JFK

    SMTWTFS
    Search

  11. AA094

    American Airlines

    19:05

    JFK

    7.2h

    08:15

    MAD

    SMTWTFS

  12. B61436

    Jetblue Airways

    09:50

    STI

    3.8h

    13:38

    JFK

    SMTWTFS
    Search

  13. AA8566

    American Airlines

    16:45

    JFK

    7.3h

    06:00

    MAD

    S-T-TFS

  14. B61736

    Jetblue Airways

    13:44

    STI

    3.8h

    17:31

    JFK

    SMTWTFS
    Search

  15. AA8566

    American Airlines

    16:45

    JFK

    7.3h

    06:00

    MAD

    S-T-TFS

  16. B61536

    Jetblue Airways

    20:10

    STI

    3.8h

    23:58

    JFK

    SMTWTFS
    Search

  17. AA8566

    American Airlines

    16:45

    JFK

    7.3h

    06:00

    MAD

    S-T-TFS

  18. UX120

    Air Europa

    22:05

    STI

    8.3h

    Nonstop

    12:20

    MAD

    -----F-
    Search

  19. B61936

    Jetblue Airways

    22:55

    STI

    3.7h

    02:37

    JFK

    SMTWTFS
    Search

  20. AA8566

    American Airlines

    16:45

    JFK

    7.3h

    06:00

    MAD

    S-T-TFS
Find more flights and airlines

When is the cheapest time to fly from Santiago to Madrid?

Price trend charts are a great way of tracking how much your flights cost in the lead up to departure and can help you choose when to book your tickets. See how prices to Madrid from Santiago have changed and are set to move below.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Santiago (STI) to Madrid (MAD) the cheapest?

    Airlines adjust prices for flights from Santiago to Madrid based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Santiago (STI) to Madrid (MAD) cost?

    According to Trip.com's data, the lowest price is around €1,345.

  • How long does it take to fly from Santiago (STI) to Madrid (MAD)?

    It takes about 8 hours 15 minutes to fly from Santiago (STI) to Madrid (MAD).

  • What is the transportation method from the main airport to downtown in Madrid?

    • The distance from Madrid Barajas Airport to downtown is about 14 km, by taxi about 30 minutes.

  • What are the most popular airlines that fly from Santiago (STI) to Madrid (MAD)?

    Airlines with flights from Santiago (STI) to Madrid (MAD): Air Europa.

  • How many airports are there in Madrid (MAD)?

    There are 1 airport(s) near Madrid (MAD): Madrid Barajas Airport.

How to find a cheap flight from Santiago to Madrid

Understanding the common pitfalls when booking your flight tickets can help you save massively when it comes time to fly. We’ve listed our six essential steps to keep in mind when you’re booking flight tickets to help you find the best price.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | Santiago to Madrid

Cheapest direct flight price€387
Cheapest return ticket price€886
Off-season for travelJanuary
Peak season for travelMay
Flight distance6,704.2 km
Average flight time8 hours 15 minutes
Popular airlineAmerican Airlines

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