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Cheap flight deals from Santo Domingo to Knoxville Starting at €432

Discover our range of affordable one-way and round-trip flights from Santo Domingo to Knoxville and kick-start your next adventure today!

  • One way
  • Round-trip
      • SDQ06:00
        29h 3m
        1 stop
        TYS11:03
        Mon, Apr 7|Santo Domingo - Knoxville|United Airlines
        €432€854
        49% OFF
        49% OFF
        €854€432

        Choose United Airlines flights from Santo Domingo to Knoxville. The one-way connecting flight with United Airlines departs from Las Américas International Airport on Mon, Apr 7, arriving at Mcghee Tyson Airport. One-way Prices start from €432 including taxes and charges.

      • SDQ05:01
        30h 2m
        1 stop
        TYS11:03
        Mon, Apr 7|Santo Domingo - Knoxville|Jetblue Airways
        €546€854
        36% OFF
        36% OFF
        €854€546

        Choose Jetblue Airways flights from Santo Domingo to Knoxville. The one-way connecting flight with Jetblue Airways departs from Las Américas International Airport on Mon, Apr 7, arriving at Mcghee Tyson Airport. One-way Prices start from €546 including taxes and charges.

      • SDQ05:00
        16h 21m
        1 stop
        TYS21:21
        Mon, Mar 24|Santo Domingo - Knoxville|United Airlines
        €561€854
        34% OFF
        34% OFF
        €854€561

        Choose United Airlines flights from Santo Domingo to Knoxville. The one-way connecting flight with United Airlines departs from Las Américas International Airport on Mon, Mar 24, arriving at Mcghee Tyson Airport. One-way Prices start from €561 including taxes and charges.

      • SDQ06:00
        15h 54m
        1 stop
        TYS20:54
        Thu, Feb 20|Santo Domingo - Knoxville|United Airlines
        €634
        €634

        Choose United Airlines flights from Santo Domingo to Knoxville. The one-way connecting flight with United Airlines departs from Las Américas International Airport on Thu, Feb 20, arriving at Mcghee Tyson Airport. One-way Prices start from €634 including taxes and charges.

      • SDQ12:04
        8h 49m
        1 stop
        TYS20:53
        Mon, Mar 24|Santo Domingo - Knoxville|Frontier Airlines
        €658
        €658

        Choose Frontier Airlines flights from Santo Domingo to Knoxville. The one-way connecting flight with Frontier Airlines departs from Las Américas International Airport on Mon, Mar 24, arriving at Mcghee Tyson Airport. One-way Prices start from €658 including taxes and charges.

      • SDQ01:00 pm
        3h 5m
        Nonstop
        TYS02:00 pm
        Sat, Feb 22|Santo Domingo - Knoxville|United Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

Santo Domingo to Knoxville flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. B61510

    Jetblue Airways

    02:35

    SDQ

    4.0h

    05:35

    JFK

    SMTWTFS
    Search

  2. UA2211

    United Airlines

    16:14

    LGA

    7.5h

    22:42

    ORD

    SMTWTFS

  3. UA1871

    United Airlines

    20:15

    ORD

    1.8h

    23:00

    TYS

    SMTWTFS

  4. B6746

    Jetblue Airways

    05:01

    SDQ

    3.9h

    08:56

    JFK

    SMTWTFS
    Search

  5. UA1412

    United Airlines

    06:00

    EWR

    1.3h

    07:17

    IAD

    SMTWTF-

  6. UA4257

    United Airlines

    08:20

    IAD

    1.8h

    10:05

    TYS

    SMTWTFS

  7. DM4500

    DM Airlines

    06:00

    SDQ

    3.3h

    07:15

    SAL

    SMT---S
    Search

  8. UA1468

    United Airlines

    13:25

    SAL

    3.1h

    17:34

    IAH

    SMTWTFS

  9. UA4890

    United Airlines

    14:35

    IAH

    2.4h

    17:56

    TYS

    SMTWTFS

  10. UA1472

    United Airlines

    06:00

    SDQ

    4.2h

    10:12

    EWR

    SMTWTFS
    Search

  11. UA2211

    United Airlines

    16:14

    LGA

    7.5h

    22:42

    ORD

    SMTWTFS

  12. UA1871

    United Airlines

    20:15

    ORD

    1.8h

    23:00

    TYS

    SMTWTFS

  13. UA1472

    United Airlines

    06:00

    SDQ

    4.2h

    10:12

    EWR

    SMTWTFS
    Search

  14. AA4674

    American Airlines

    20:13

    LGA

    2.5h

    22:45

    TYS

    SMTWT-S

  15. F9180

    Frontier Airlines

    12:28

    SDQ

    4.0h

    16:27

    PHL

    S---TF-
    Search

  16. AA5352

    American Airlines

    18:50

    PHL

    2.0h

    20:53

    TYS

    SMTWTFS

  17. B62448

    Jetblue Airways

    14:29

    SDQ

    2.5h

    16:59

    FLL

    SMTWTFS
    Search

  18. UA403

    United Airlines

    16:05

    FLL

    3.5h

    18:35

    ORD

    SMTWTFS

  19. UA1871

    United Airlines

    20:15

    ORD

    1.8h

    23:00

    TYS

    SMTWTFS

  20. NK142

    Spirit Airlines

    18:19

    SDQ

    1.5h

    19:50

    FLL

    SMTWTFS
    Search

  21. UA754

    United Airlines

    20:20

    FLL

    4.6h

    22:57

    DEN

    SMTWT-S

  22. UA5383

    United Airlines

    10:10

    DEN

    2.9h

    15:06

    TYS

    SMTWTFS

  23. B62510

    Jetblue Airways

    21:10

    SDQ

    4.0h

    01:10

    JFK

    SMTWTFS
    Search

  24. AA4674

    American Airlines

    20:13

    LGA

    2.5h

    22:45

    TYS

    SMTWT-S

  25. B62510

    Jetblue Airways

    21:10

    SDQ

    4.0h

    01:10

    JFK

    SMTWTFS
    Search

  26. AA4761

    American Airlines

    14:34

    LGA

    2.7h

    17:15

    TYS

    SMTWTFS
Find more flights and airlines

When is the cheapest time to fly from Santo Domingo to Knoxville?

Explore the best time to buy affordable tickets to Knoxville with our price trend chart, which predicts how flight prices will change in the coming weeks from previous data.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from Santo Domingo (SDQ) to Knoxville (TYS) the cheapest?

    Airlines adjust prices for flights from Santo Domingo to Knoxville based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from Santo Domingo (SDQ) to Knoxville (TYS) cost?

    According to Trip.com's data, the lowest price is around €614.

  • How many airports are there in Knoxville (TYS)?

    There are 1 airport(s) near Knoxville (TYS): Mcghee Tyson Airport.

How to find a cheap flight from Santo Domingo to Knoxville

Understanding the common pitfalls when booking your flight tickets can help you save massively when it comes time to fly. We’ve listed our six essential steps to keep in mind when you’re booking flight tickets to help you find the best price.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | Santo Domingo to Knoxville

Cheapest direct flight price€431
Off-season for travelFebruary
Peak season for travelMay
Flight distance2,374 km
Popular airlineJetblue Airways

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