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Cheap flight deals from St. Louis to Madrid Starting at AED 1,280

Discover our range of affordable one-way and round-trip flights from St. Louis to Madrid and kick-start your next adventure today!

  • One way
  • Round-trip
      • STL07:29
        16h 36m
        1 stop
        MAD06:05
        Tue, Mar 18|St. Louis - Madrid|American Airlines
        AED 1,280AED 2,303
        44% OFF
        44% OFF
        AED 2,303AED 1,280

        Choose American Airlines flights from St. Louis to Madrid. The one-way connecting flight with American Airlines departs from St. Louis Lambert International Airport on Tue, Mar 18, arriving at Madrid Barajas Airport. One-way Prices start from AED 1,280 including taxes and charges.

      • STL07:30
        16h 35m
        1 stop
        MAD06:05
        Tue, Mar 18|St. Louis - Madrid|United Airlines
        AED 1,401AED 2,303
        39% OFF
        39% OFF
        AED 2,303AED 1,401

        Choose United Airlines flights from St. Louis to Madrid. The one-way connecting flight with United Airlines departs from St. Louis Lambert International Airport on Tue, Mar 18, arriving at Madrid Barajas Airport. One-way Prices start from AED 1,401 including taxes and charges.

      • STL12:58
        15h 17m
        1 stop
        MAD10:15
        Mon, Mar 10|St. Louis - Madrid|American Airlines
        AED 1,577AED 2,303
        32% OFF
        32% OFF
        AED 2,303AED 1,577

        Choose American Airlines flights from St. Louis to Madrid. The one-way connecting flight with American Airlines departs from St. Louis Lambert International Airport on Mon, Mar 10, arriving at Madrid Barajas Airport. One-way Prices start from AED 1,577 including taxes and charges.

      • STL07:10
        18h 50m
        1 stop
        MAD08:00
        Mon, Mar 24|St. Louis - Madrid|Delta Air Lines
        AED 1,676
        AED 1,676

        Choose Delta Air Lines flights from St. Louis to Madrid. The one-way connecting flight with Delta Air Lines departs from St. Louis Lambert International Airport on Mon, Mar 24, arriving at Madrid Barajas Airport. One-way Prices start from AED 1,676 including taxes and charges.

      • STL12:00
        14h 15m
        1 stop
        MAD09:15
        Tue, Feb 25|St. Louis - Madrid|United Airlines
        AED 1,681
        AED 1,681

        Choose United Airlines flights from St. Louis to Madrid. The one-way connecting flight with United Airlines departs from St. Louis Lambert International Airport on Tue, Feb 25, arriving at Madrid Barajas Airport. One-way Prices start from AED 1,681 including taxes and charges.

      • STL13:06
        12h 54m
        1 stop
        MAD08:00
        Wed, Mar 12|St. Louis - Madrid|Virgin Atlantic
        AED 1,688
        AED 1,688

        Choose Virgin Atlantic flights from St. Louis to Madrid. The one-way connecting flight with Virgin Atlantic departs from St. Louis Lambert International Airport on Wed, Mar 12, arriving at Madrid Barajas Airport. One-way Prices start from AED 1,688 including taxes and charges.

      • STL16:45
        33h 15m
        1 stop
        MAD08:00
        Mon, Mar 24|St. Louis - Madrid|Virgin Atlantic
        AED 1,694
        AED 1,694

        Choose Virgin Atlantic flights from St. Louis to Madrid. The one-way connecting flight with Virgin Atlantic departs from St. Louis Lambert International Airport on Mon, Mar 24, arriving at Madrid Barajas Airport. One-way Prices start from AED 1,694 including taxes and charges.

      • STL16:42
        14h 8m
        1 stop
        MAD12:50
        Mon, Mar 24|St. Louis - Madrid|American Airlines
        AED 1,699
        AED 1,699

        Choose American Airlines flights from St. Louis to Madrid. The one-way connecting flight with American Airlines departs from St. Louis Lambert International Airport on Mon, Mar 24, arriving at Madrid Barajas Airport. One-way Prices start from AED 1,699 including taxes and charges.

      • STL12:52
        13h 8m
        1 stop
        MAD09:00
        Tue, Feb 25|St. Louis - Madrid|Delta Air Lines
        AED 1,699
        AED 1,699

        Choose Delta Air Lines flights from St. Louis to Madrid. The one-way connecting flight with Delta Air Lines departs from St. Louis Lambert International Airport on Tue, Feb 25, arriving at Madrid Barajas Airport. One-way Prices start from AED 1,699 including taxes and charges.

      • STL10:59
        15h 1m
        1 stop
        MAD09:00
        Tue, Feb 25|St. Louis - Madrid|Virgin Atlantic
        AED 1,704
        AED 1,704

        Choose Virgin Atlantic flights from St. Louis to Madrid. The one-way connecting flight with Virgin Atlantic departs from St. Louis Lambert International Airport on Tue, Feb 25, arriving at Madrid Barajas Airport. One-way Prices start from AED 1,704 including taxes and charges.

      • STL01:00 pm
        3h 5m
        Nonstop
        MAD02:00 pm
        Fri, Feb 28|St. Louis - Madrid|American Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

St. Louis to Madrid flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. VS5368

    Virgin Atlantic

    10:10

    STL

    1.6h

    12:46

    ATL

    SMTWTFS
    Search

  2. VS3884

    Virgin Atlantic

    19:15

    ATL

    8.3h

    09:35

    MAD

    --T-T--

  3. UA3684

    United Airlines

    11:49

    STL

    2.6h

    15:27

    EWR

    SMTWTFS
    Search

  4. UA051

    United Airlines

    19:25

    EWR

    7.6h

    09:00

    MAD

    SMTWTFS

  5. AA4479

    American Airlines

    12:32

    STL

    2.5h

    16:00

    LGA

    SMTWTFS
    Search

  6. AA8567

    American Airlines

    20:40

    JFK

    7.4h

    10:05

    MAD

    SMTWTFS

  7. VS5370

    Virgin Atlantic

    12:55

    STL

    1.6h

    15:33

    ATL

    SMTWTFS
    Search

  8. VS3884

    Virgin Atlantic

    19:15

    ATL

    8.3h

    09:35

    MAD

    --T-T--

  9. IB4224

    Iberia

    13:45

    STL

    2.2h

    16:55

    PHL

    SMTWT-S
    Search

  10. IB4918

    Iberia

    21:15

    PHL

    6.8h

    09:05

    LIS

    SMTWTFS

  11. U27645

    easyJet

    12:50

    LIS

    1.3h

    15:10

    MAD

    SMTWTFS

  12. BA5694

    British Airways

    13:45

    STL

    2.2h

    16:55

    PHL

    SMTWT-S
    Search

  13. BA1605

    British Airways

    20:30

    PHL

    7.1h

    09:35

    MAD

    SMTWTFS

  14. IB4224

    Iberia

    13:45

    STL

    2.2h

    16:55

    PHL

    SMTWT-S
    Search

  15. IB4674

    Iberia

    20:30

    PHL

    7.1h

    09:35

    MAD

    SMTWTFS

  16. DL566

    Delta Air Lines

    14:05

    STL

    1.7h

    16:45

    ATL

    SMTWTFS
    Search

  17. DL108

    Delta Air Lines

    19:15

    ATL

    8.3h

    09:35

    MAD

    -M-W---

  18. LH449

    Lufthansa

    15:30

    STL

    8.9h

    07:25

    FRA

    --T-T-S
    Search

  19. LH1166

    Lufthansa

    09:15

    FRA

    3.2h

    11:25

    LIS

    SM-WT-S

  20. U27645

    easyJet

    12:50

    LIS

    1.3h

    15:10

    MAD

    SMTWTFS

  21. AA3659

    American Airlines

    16:33

    STL

    2.9h

    20:24

    MIA

    SMTWTFS
    Search

  22. IB338

    Iberia

    22:05

    MIA

    8.7h

    12:45

    MAD

    SMTWTFS
Find more flights and airlines

When is the cheapest time to fly from St. Louis to Madrid?

Explore the best time to buy affordable tickets to Madrid with our price trend chart, which predicts how flight prices will change in the coming weeks from previous data.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from St. Louis (STL) to Madrid (MAD) the cheapest?

    Airlines adjust prices for flights from St. Louis to Madrid based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from St. Louis (STL) to Madrid (MAD) cost?

    According to Trip.com's data, the lowest price is around AED 3,961.

  • What is the transportation method from the main airport to downtown in Madrid?

    • The distance from Madrid Barajas Airport to downtown is about 14 km, by taxi about 30 minutes.

  • How many airports are there in Madrid (MAD)?

    There are 1 airport(s) near Madrid (MAD): Madrid Barajas Airport.

How to find a cheap flight from St. Louis to Madrid

Understanding the common pitfalls when booking your flight tickets can help you save massively when it comes time to fly. We’ve listed our six essential steps to keep in mind when you’re booking flight tickets to help you find the best price.
1
Being flexible with your dates to get the cheapest St. Louis to Madrid ticket.
Tap "Date" on flight search bar to scan through the calender for St. Louis to Madrid airfare over next 6 months in 2025. If you would like to fly in next 3 months, it seems the cheapest date is on Tue, Mar 18 at AED 1280 for one-way flights.
2
Compare cheap St. Louis to Madrid flight deals from over hundreds of airlines.
Our extensive search allows you to compare prices from over 500 airlines to choose the cheapest flight tickets from St. Louis to Madrid. The cheapest airline operating is American Airlines.
3
Set up a Price Alert
By setting up a Price Alert for your St. Louis to Madrid route, you can easily track the price of your airline tickets from without manually checking every day.
4
Don't miss cheap St. Louis to Madrid flight deals and promo codes.
You can always get the latest deals through Trip.com Deals and Promo Codes for cheap flights. If registering a free membership, you can receive more deals for your flights.
5
Book early or wait unitl the last minute.
It's always better to book early. Flight tickets tend to be the cheapest when they are first released, normally about a year before the departure date. So, check online as soon as the flights you want become available. If you miss the cheapest time, you can still find lower-priced tickets as the flight date approaches.
6
Search for flights on the go.
To get the best flight booking experience on the go, download Trip.com and search for cheap flight tickets from St. Louis to Madrid to get exclusive deals for you.

Flight Info | St. Louis to Madrid

Cheapest direct flight priceAED 1,279
Off-season for travelJanuary
Peak season for travelNovember
Flight distance7,104 km
Popular airlineBritish Airways

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