App
Customer Support
AED
Find Bookings
Trip.com
>
Flights
>
Flights to United States
>
Flights to Panama City
>
Flights from St. Louis to Panama City
Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Cheap flight deals from St. Louis to Panama City Starting at AED 612

Whether you’re going for a one-way or round-trip to Panama City, we’ve got you covered! Check out these different flight options from St. Louis below.

  • One way
  • Round-trip
      • STL16:11
        3h 29m
        1 stop
        ECP19:40
        Wed, Apr 16|St. Louis - Panama City|Delta Air Lines
        AED 612AED 840
        27% OFF
        27% OFF
        AED 840AED 612

        Choose Delta Air Lines flights from St. Louis to Panama City. The one-way connecting flight with Delta Air Lines departs from St. Louis Lambert International Airport on Wed, Apr 16, arriving at Northwest Florida Beaches International Airport. One-way Prices start from AED 612 including taxes and charges.

      • STL16:40
        6h 23m
        1 stop
        ECP23:03
        Wed, Mar 5|St. Louis - Panama City|Delta Air Lines
        AED 612AED 840
        27% OFF
        27% OFF
        AED 840AED 612

        Choose Delta Air Lines flights from St. Louis to Panama City. The one-way connecting flight with Delta Air Lines departs from St. Louis Lambert International Airport on Wed, Mar 5, arriving at Northwest Florida Beaches International Airport. One-way Prices start from AED 612 including taxes and charges.

      • STL19:07
        3h 56m
        1 stop
        ECP23:03
        Thu, Mar 6|St. Louis - Panama City|Delta Air Lines
        AED 612AED 840
        27% OFF
        27% OFF
        AED 840AED 612

        Choose Delta Air Lines flights from St. Louis to Panama City. The one-way connecting flight with Delta Air Lines departs from St. Louis Lambert International Airport on Thu, Mar 6, arriving at Northwest Florida Beaches International Airport. One-way Prices start from AED 612 including taxes and charges.

      • STL06:00
        6h 20m
        1 stop
        ECP12:20
        Wed, Mar 12|St. Louis - Panama City|Delta Air Lines
        AED 612
        AED 612

        Choose Delta Air Lines flights from St. Louis to Panama City. The one-way connecting flight with Delta Air Lines departs from St. Louis Lambert International Airport on Wed, Mar 12, arriving at Northwest Florida Beaches International Airport. One-way Prices start from AED 612 including taxes and charges.

      • STL06:00
        4h 17m
        1 stop
        ECP10:17
        Tue, Mar 25|St. Louis - Panama City|Delta Air Lines
        AED 615
        AED 615

        Choose Delta Air Lines flights from St. Louis to Panama City. The one-way connecting flight with Delta Air Lines departs from St. Louis Lambert International Airport on Tue, Mar 25, arriving at Northwest Florida Beaches International Airport. One-way Prices start from AED 615 including taxes and charges.

      • STL16:45
        6h 19m
        1 stop
        ECP23:04
        Mon, Mar 17|St. Louis - Panama City|Delta Air Lines
        AED 616
        AED 616

        Choose Delta Air Lines flights from St. Louis to Panama City. The one-way connecting flight with Delta Air Lines departs from St. Louis Lambert International Airport on Mon, Mar 17, arriving at Northwest Florida Beaches International Airport. One-way Prices start from AED 616 including taxes and charges.

      • STL06:00
        6h 5m
        1 stop
        ECP12:05
        Tue, Feb 25|St. Louis - Panama City|Delta Air Lines
        AED 617
        AED 617

        Choose Delta Air Lines flights from St. Louis to Panama City. The one-way connecting flight with Delta Air Lines departs from St. Louis Lambert International Airport on Tue, Feb 25, arriving at Northwest Florida Beaches International Airport. One-way Prices start from AED 617 including taxes and charges.

      • STL19:10
        3h 54m
        1 stop
        ECP23:04
        Thu, Mar 27|St. Louis - Panama City|Delta Air Lines
        AED 686
        AED 686

        Choose Delta Air Lines flights from St. Louis to Panama City. The one-way connecting flight with Delta Air Lines departs from St. Louis Lambert International Airport on Thu, Mar 27, arriving at Northwest Florida Beaches International Airport. One-way Prices start from AED 686 including taxes and charges.

      • STL16:40
        6h 23m
        1 stop
        ECP23:03
        Sat, Mar 1|St. Louis - Panama City|Delta Air Lines
        AED 693
        AED 693

        Choose Delta Air Lines flights from St. Louis to Panama City. The one-way connecting flight with Delta Air Lines departs from St. Louis Lambert International Airport on Sat, Mar 1, arriving at Northwest Florida Beaches International Airport. One-way Prices start from AED 693 including taxes and charges.

      • STL19:07
        3h 56m
        1 stop
        ECP23:03
        Sun, Mar 2|St. Louis - Panama City|Delta Air Lines
        AED 733
        AED 733

        Choose Delta Air Lines flights from St. Louis to Panama City. The one-way connecting flight with Delta Air Lines departs from St. Louis Lambert International Airport on Sun, Mar 2, arriving at Northwest Florida Beaches International Airport. One-way Prices start from AED 733 including taxes and charges.

      • STL01:00 pm
        3h 5m
        Nonstop
        ECP02:00 pm
        Sun, Feb 23|St. Louis - Panama City|Delta Air Lines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

St. Louis to Panama City flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. AA1515

    American Airlines

    05:12

    STL

    2.0h

    08:10

    CLT

    S-TWTFS
    Search

  2. AA5327

    American Airlines

    09:10

    CLT

    1.9h

    10:04

    ECP

    SMTWTFS

  3. DL1524

    Delta Air Lines

    06:00

    STL

    1.8h

    08:45

    ATL

    SMTWTFS
    Search

  4. DL3045

    Delta Air Lines

    10:05

    ATL

    1.1h

    10:13

    ECP

    SMTWTFS

  5. UA6199

    United Airlines

    06:15

    STL

    2.4h

    08:41

    IAH

    SMTWTFS
    Search

  6. UA4308

    United Airlines

    10:00

    IAH

    1.9h

    11:52

    ECP

    SMTWTFS

  7. DL1536

    Delta Air Lines

    07:20

    STL

    1.7h

    10:02

    ATL

    SMTWTFS
    Search

  8. DL3045

    Delta Air Lines

    10:05

    ATL

    1.1h

    10:13

    ECP

    SMTWTFS

  9. AA2493

    American Airlines

    08:59

    STL

    1.9h

    11:50

    CLT

    SMTW-FS
    Search

  10. AA5059

    American Airlines

    15:13

    CLT

    1.7h

    15:55

    ECP

    SMTWTFS

  11. AA2480

    American Airlines

    09:29

    STL

    2.1h

    11:33

    DFW

    SMTWTFS
    Search

  12. AA1739

    American Airlines

    13:06

    DFW

    1.7h

    14:49

    ECP

    SMTWTFS

  13. DL1571

    Delta Air Lines

    10:10

    STL

    1.6h

    12:47

    ATL

    SMTWTFS
    Search

  14. DL3053

    Delta Air Lines

    17:45

    ATL

    1.1h

    17:51

    ECP

    SMTWTFS

  15. UA2121

    United Airlines

    16:50

    STL

    2.3h

    19:06

    IAH

    SMTWTFS
    Search

  16. UA6130

    United Airlines

    20:13

    IAH

    1.6h

    21:52

    ECP

    S-TWTFS

  17. DL1393

    Delta Air Lines

    19:05

    STL

    1.7h

    21:46

    ATL

    S--WT-S
    Search

  18. DL3131

    Delta Air Lines

    22:35

    ATL

    1.1h

    22:42

    ECP

    SMTWTFS

  19. WN2215

    Southwest Airlines

    20:20

    STL

    1.2h

    21:30

    BNA

    SMTWT-S
    Search

  20. WN2521

    Southwest Airlines

    18:45

    BNA

    1.5h

    20:15

    ECP

    SMTWT-S
Find more flights and airlines

When is the cheapest time to fly from St. Louis to Panama City?

Explore the best time to buy affordable tickets to Panama City with our price trend chart, which predicts how flight prices will change in the coming weeks from previous data.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from St. Louis (STL) to Panama City (ECP) the cheapest?

    Airlines adjust prices for flights from St. Louis to Panama City based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from St. Louis (STL) to Panama City (ECP) cost?

    According to Trip.com's data, the lowest price is around AED 1,884.

  • What's the most popular airline for non-stop flights from St. Louis (STL) to Panama City (ECP)?

    Southwest Airlines operates 1 non-stop flights from St. Louis (STL) to Panama City (ECP).

  • How many airports are there in Panama City (ECP)?

    There are 1 airport(s) near Panama City (ECP): Northwest Florida Beaches International Airport.

How to find a cheap flight from St. Louis to Panama City

If you leave it until the last minute and forget to check some of the key information when booking tickets, prices can often end up skyrocketing. Below, you can find our top tips for getting the best value flights – from changing dates to chasing deals, there are plenty ways to keep your next trip affordable.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | St. Louis to Panama City

Cheapest direct flight priceAED 611
Off-season for travelMarch
Peak season for travelDecember
Flight distance1,025.63 km
Popular airlineUnited Airlines

Contact Us

About

Other Services

Payment Methods
Our Partners
Copyright © 2025 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.