App
Customer Support
EUR
Find Bookings
Worldwide Coverage
Worldwide Coverage
Flights to over 5,000 cities
One-stop Service Guarantee
One-stop Service Guarantee
Price guaranteed upon confirmed payment, booking guaranteed once tickets issued
Secure Payment
Secure Payment
Convenient & reliable booking and payment system

Cheap flight deals from St. Louis to San Diego Starting at €35

For as little as €35, you can take your next adventure to San Diego without breaking the bank. Choose between one-way and return tickets from St. Louis below.

  • One way
  • Round-trip
      • Cheapest nonstop
        STL08:40
        4h 5m
        Nonstop
        SAN10:45
        Sat, Mar 29|St. Louis - San Diego|Southwest Airlines
        €182€245
        26% OFF
        26% OFF
        €245€182

        Choose Southwest Airlines flights from St. Louis to San Diego. The one-way direct flight with Southwest Airlines departs from St. Louis Lambert International Airport on Sat, Mar 29, arriving at San Diego International Airport. One-way Prices start from €182 including taxes and charges.

      • STL06:00
        4h 10m
        Nonstop
        SAN08:10
        Mon, Mar 24|St. Louis - San Diego|Southwest Airlines
        €216€245
        12% OFF
        12% OFF
        €245€216

        Choose Southwest Airlines flights from St. Louis to San Diego. The one-way direct flight with Southwest Airlines departs from St. Louis Lambert International Airport on Mon, Mar 24, arriving at San Diego International Airport. One-way Prices start from €216 including taxes and charges.

      • STL19:04
        7h 16m
        1 stop
        SAN00:20
        Sat, Mar 1|St. Louis - San Diego|Frontier Airlines
        €35€245
        86% OFF
        86% OFF
        €245€35

        Choose Frontier Airlines flights from St. Louis to San Diego. The one-way connecting flight with Frontier Airlines departs from St. Louis Lambert International Airport on Sat, Mar 1, arriving at San Diego International Airport. One-way Prices start from €35 including taxes and charges.

      • STL19:04
        7h 16m
        1 stop
        SAN00:20
        Wed, Mar 5|St. Louis - San Diego|Frontier Airlines
        €48
        €48

        Choose Frontier Airlines flights from St. Louis to San Diego. The one-way connecting flight with Frontier Airlines departs from St. Louis Lambert International Airport on Wed, Mar 5, arriving at San Diego International Airport. One-way Prices start from €48 including taxes and charges.

      • STL16:07
        5h 47m
        1 stop
        SAN19:54
        Thu, May 1|St. Louis - San Diego|Frontier Airlines
        €53
        €53

        Choose Frontier Airlines flights from St. Louis to San Diego. The one-way connecting flight with Frontier Airlines departs from St. Louis Lambert International Airport on Thu, May 1, arriving at San Diego International Airport. One-way Prices start from €53 including taxes and charges.

      • STL18:51
        7h 26m
        1 stop
        SAN00:17
        Sat, Apr 12|St. Louis - San Diego|Frontier Airlines
        €55
        €55

        Choose Frontier Airlines flights from St. Louis to San Diego. The one-way connecting flight with Frontier Airlines departs from St. Louis Lambert International Airport on Sat, Apr 12, arriving at San Diego International Airport. One-way Prices start from €55 including taxes and charges.

      • STL18:51
        7h 23m
        1 stop
        SAN00:14
        Wed, Apr 30|St. Louis - San Diego|Frontier Airlines
        €56
        €56

        Choose Frontier Airlines flights from St. Louis to San Diego. The one-way connecting flight with Frontier Airlines departs from St. Louis Lambert International Airport on Wed, Apr 30, arriving at San Diego International Airport. One-way Prices start from €56 including taxes and charges.

      • STL23:08
        22h 10m
        1 stop
        SAN19:18
        Thu, Feb 27|St. Louis - San Diego|Frontier Airlines
        €58
        €58

        Choose Frontier Airlines flights from St. Louis to San Diego. The one-way connecting flight with Frontier Airlines departs from St. Louis Lambert International Airport on Thu, Feb 27, arriving at San Diego International Airport. One-way Prices start from €58 including taxes and charges.

      • STL23:08
        22h 10m
        1 stop
        SAN19:18
        Thu, Feb 20|St. Louis - San Diego|Frontier Airlines
        €60
        €60

        Choose Frontier Airlines flights from St. Louis to San Diego. The one-way connecting flight with Frontier Airlines departs from St. Louis Lambert International Airport on Thu, Feb 20, arriving at San Diego International Airport. One-way Prices start from €60 including taxes and charges.

      • STL23:08
        22h 10m
        1 stop
        SAN19:18
        Mon, Feb 24|St. Louis - San Diego|Frontier Airlines
        €61
        €61

        Choose Frontier Airlines flights from St. Louis to San Diego. The one-way connecting flight with Frontier Airlines departs from St. Louis Lambert International Airport on Mon, Feb 24, arriving at San Diego International Airport. One-way Prices start from €61 including taxes and charges.

      • STL01:00 pm
        3h 5m
        Nonstop
        SAN02:00 pm
        Sun, Feb 23|St. Louis - San Diego|Southwest Airlines
        Find More Flights
        Find More Flights

Crossed out prices are calculated based on the average price of the corresponding route on Trip.com.

St. Louis to San Diego flight time & flight schedules

Flight info.
Departure
Arrival
Weekly Schedule

  1. AS504

    Alaska Airlines

    06:30

    STL

    4.3h

    08:47

    SEA

    SMTWTFS
    Search

  2. AS1180

    Alaska Airlines

    11:02

    SEA

    2.8h

    13:50

    SAN

    SMTWTFS

  3. DL1571

    Delta Air Lines

    10:10

    STL

    1.6h

    12:46

    ATL

    SMTWTFS
    Search

  4. DL712

    Delta Air Lines

    19:50

    ATL

    4.8h

    21:37

    SAN

    SMTWTFS

  5. F93641

    Frontier Airlines

    13:06

    STL

    3.8h

    14:51

    LAS

    SMTW-F-
    Search

  6. F91465

    Frontier Airlines

    22:42

    LAS

    1.3h

    23:58

    SAN

    SMTWTF-

  7. F93641

    Frontier Airlines

    13:06

    STL

    3.8h

    14:51

    LAS

    SMTW-F-
    Search

  8. F91469

    Frontier Airlines

    12:10

    LAS

    1.4h

    13:37

    SAN

    ---W-FS

  9. DL1492

    Delta Air Lines

    17:00

    STL

    3.3h

    19:15

    SLC

    SMTWTFS
    Search

  10. DL1202

    Delta Air Lines

    21:35

    SLC

    2.0h

    22:33

    SAN

    SMTWTFS

  11. DL1485

    Delta Air Lines

    17:40

    STL

    1.8h

    20:25

    ATL

    SMTWTFS
    Search

  12. DL896

    Delta Air Lines

    21:15

    ATL

    4.8h

    23:03

    SAN

    SMTWTFS

  13. F94567

    Frontier Airlines

    18:53

    STL

    2.5h

    20:22

    DEN

    S-T-TF-
    Search

  14. F94927

    Frontier Airlines

    10:05

    DEN

    2.7h

    11:48

    SAN

    SMTWTFS

  15. F94567

    Frontier Airlines

    18:53

    STL

    2.5h

    20:22

    DEN

    S-T-TF-
    Search

  16. F92817

    Frontier Airlines

    08:05

    DEN

    2.5h

    09:38

    SAN

    -M-WTF-

  17. F94567

    Frontier Airlines

    18:53

    STL

    2.5h

    20:22

    DEN

    S-T-TF-
    Search

  18. F94989

    Frontier Airlines

    18:22

    DEN

    2.5h

    19:54

    SAN

    SMTWTFS

  19. F92017

    Frontier Airlines

    21:55

    STL

    3.8h

    23:41

    LAS

    S--WT-S
    Search

  20. F91465

    Frontier Airlines

    22:42

    LAS

    1.3h

    23:58

    SAN

    SMTWTF-
Find more flights and airlines

When is the cheapest time to fly from St. Louis to San Diego?

Price trend charts are a great way of tracking how much your flights cost in the lead up to departure and can help you choose when to book your tickets. See how prices to San Diego from St. Louis have changed and are set to move below.

Displayed prices are calculated based on the cheapest average weekly prices of the corresponding route on Trip.com.

Frequently Asked Questions

  • When are flight tickets from St. Louis (STL) to San Diego (SAN) the cheapest?

    Airlines adjust prices for flights from St. Louis to San Diego based on the date and time of your booking. By analyzing data from all airlines, on Trip.com, you can find the lowest flight prices on Tuesdays, Wednesdays, and Saturdays.

  • How much do flights from St. Louis (STL) to San Diego (SAN) cost?

    According to Trip.com's data, the lowest price is around €322.

  • How long does it take to fly from St. Louis (STL) to San Diego (SAN)?

    It takes about 4 hours 52 minutes to fly from St. Louis (STL) to San Diego (SAN).

  • What is the transportation method from the main airport to downtown in San Diego?

    • The distance from San Diego International Airport to downtown is about 3 km, by taxi about 20 minutes.

  • What are the most popular airlines that fly from St. Louis (STL) to San Diego (SAN)?

    Airlines with flights from St. Louis (STL) to San Diego (SAN): Southwest Airlines.

  • What's the most popular airline for non-stop flights from St. Louis (STL) to San Diego (SAN)?

    Southwest Airlines operates 1 non-stop flights from St. Louis (STL) to San Diego (SAN).

  • How many airports are there in San Diego (SAN)?

    There are 2 airport(s) near San Diego (SAN): McClellan-Palomar Airport and San Diego International Airport.

How to find a cheap flight from St. Louis to San Diego

Understanding the common pitfalls when booking your flight tickets can help you save massively when it comes time to fly. We’ve listed our six essential steps to keep in mind when you’re booking flight tickets to help you find the best price.
1
Book Early
Once prices are gone, they're gone. Lock in deals while you can!
2
Compare Flight Prices
Compare prices on travel agency and airline websites.
3
Look Out for Deals
Check airline and travel agency websites for latest flight deals
4
Check One-way Fares
Buying two cheap one-way flights can sometimes be a better deal than a round-trip.
5
Try Different Dates
Flying during the week, early in the morning, or late at night can help save money.
6
Use the Trip.com App
Save up to £10 per person when booking your flights on Trip.com

Flight Info | St. Louis to San Diego

Cheapest direct flight price€35
Cheapest return ticket price€200
Off-season for travelMarch
Peak season for travelMay
Flight distance2,514.9 km
Average flight time4 hours 52 minutes
Popular airlineAlaska Airlines

Contact Us

About

Other Services

Payment Methods
Our Partners
Copyright © 2025 Trip.com Travel Singapore Pte. Ltd. All rights reserved
Site Operator: Trip.com Travel Singapore Pte. Ltd.