Hotels in Seneca

Best Seneca Hotels

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10 Best Hotels to Stay in Seneca

Trip.com brings you a curated list of top accommodations in Seneca, complete with reviews, price insights, and amenity highlights, making it easy to find the perfect place to stay.
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Best Western Seneca-Clemson Hotels in Seneca
Best Western Seneca-Clemson Hotels in SenecaBest Western Seneca-Clemson Hotels in SenecaBest Western Seneca-Clemson Hotels in SenecaBest Western Seneca-Clemson Hotels in SenecaBest Western Seneca-Clemson Hotels in SenecaBest Western Seneca-Clemson Hotels in Seneca
46
Hotels in Seneca
Public parking
24-hour front desk
Wake-up call
+3
"My experience will gyood. The front desk clerk is very kind."
Very Good
102 reviews
8.3/10
1 night
From AED 369
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Historic Seneca Bungalow Hotels in Seneca
Historic Seneca Bungalow Hotels in SenecaHistoric Seneca Bungalow Hotels in SenecaHistoric Seneca Bungalow Hotels in SenecaHistoric Seneca Bungalow Hotels in SenecaHistoric Seneca Bungalow Hotels in SenecaHistoric Seneca Bungalow Hotels in Seneca
28
Hotels in Seneca
Wi-Fi in public areas
This location is perfect to relax with boutique shopping and eating on Ram Cat Alley in downtown Seneca only 2 blocks away, zip over to Clemson University (10 minute drive to the stadium) and catch a game, or drop your boat in Lake Keowee or Lake Hartwell and float to your heart's desire. This quaint, historic house has been updated for comfort keeping the original charm in its peaceful location just far enough off the beaten path to be quiet but close enough to reach any number of shops.About pets:No pets allowed.About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 3-17.About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 25.About events:No events allowed.
Outstanding
18 reviews
9.8/10
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Hampton Inn & Suites Seneca-Clemson Area Hotels in Seneca
Hampton Inn & Suites Seneca-Clemson Area Hotels in SenecaHampton Inn & Suites Seneca-Clemson Area Hotels in SenecaHampton Inn & Suites Seneca-Clemson Area Hotels in SenecaHampton Inn & Suites Seneca-Clemson Area Hotels in SenecaHampton Inn & Suites Seneca-Clemson Area Hotels in SenecaHampton Inn & Suites Seneca-Clemson Area Hotels in Seneca
99+
Hotels in Seneca
Public parking
EV charging station
Gym
+8
Welcome to the Hampton Inn & Suites Seneca-Clemson Area, a warm and welcoming hotel just a short distance from Lake Keowee and downtown Seneca, SC. Enjoy easy access to local restaurants, state parks, lakes and leisure amenities including golf. Popular Seneca attractions including the Blue Ridge Mountains, the World of Energy and Clemson University are all close to our relaxed hotel in Seneca, SC. Settle in to a beautifully decorated guest room or suite, where you can stay connected with free WiFi at the ergonomic desk, watch the satellite TV and get a great night's sleep on the clean and fresh Hampton bed. Other great amenities include an in-room microwave and refrigerator and guest laundry facilities are available at this Seneca hotel. Every morning, enjoy Hampton's free hot breakfast buffet, offering everything from light continental favorites to hot items and buy snacks at any time from the 24-hour Suite Shop. Enjoy free tea and coffee in the modern lobby, 24-hours a day and ask our friendly staff for advice on what to see and do during your stay. Stay connected with the free business center or hold a meeting in the 600 sq.ft. conference room. Energize in the free fitness center, swim in the outdoor, saltwater pool or relax under an umbrella on the poolside patio area. Friendly service, clean rooms, comfortable surroundings, every time. If you're not satisfied, we don't expect you to pay. That's our commitment and your guarantee. That's 100% Hampton.
Great
96 reviews
9.2/10
1 night
From AED 465
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Fairfield Inn & Suites Seneca Clemson Univ Area Hotels in Seneca
Fairfield Inn & Suites Seneca Clemson Univ Area Hotels in SenecaFairfield Inn & Suites Seneca Clemson Univ Area Hotels in SenecaFairfield Inn & Suites Seneca Clemson Univ Area Hotels in SenecaFairfield Inn & Suites Seneca Clemson Univ Area Hotels in SenecaFairfield Inn & Suites Seneca Clemson Univ Area Hotels in SenecaFairfield Inn & Suites Seneca Clemson Univ Area Hotels in Seneca
84
Hotels in Seneca
Gym
24-hour front desk
Wi-Fi in public areas
"Very clean, the surrounding environment is also very beautiful, there is also breakfast, a very cost-effective hotel"
Great
76 reviews
9.2/10
1 night
From AED 443
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Beautiful Home on Lake Keowee- Deep Water Dock- 4bd/4ba -Close to Clemson Hotels in Seneca
Beautiful Home on Lake Keowee- Deep Water Dock- 4bd/4ba -Close to Clemson Hotels in SenecaBeautiful Home on Lake Keowee- Deep Water Dock- 4bd/4ba -Close to Clemson Hotels in SenecaBeautiful Home on Lake Keowee- Deep Water Dock- 4bd/4ba -Close to Clemson Hotels in SenecaBeautiful Home on Lake Keowee- Deep Water Dock- 4bd/4ba -Close to Clemson Hotels in SenecaBeautiful Home on Lake Keowee- Deep Water Dock- 4bd/4ba -Close to Clemson Hotels in SenecaBeautiful Home on Lake Keowee- Deep Water Dock- 4bd/4ba -Close to Clemson Hotels in Seneca
29
Hotels in Seneca
Golf course
Horse riding
Hiking
+2
Our home is situated on a quiet cul-de-sac that shares a point at the south end of Lake Keowee with a panoramic view of Lake Keowee. Our home is just 11 miles from Clemson and is minutes by boat to South Cove boat ramp and Keowee Marina. Also, we are close to town for shopping, restaurants, groceries, pharmacy and the hospital. Our home is family friendly sleeping up to 15 people. We feature very deep water with a very large covered dock that easily holds three boats. Each bedroom has amazing views of Lake Keowee. Four bedrooms with 4 full bathrooms includes a bunk room for kids. The home is located on a gentle sloping lot. Two Master King bedrooms on the main floor with attached bathrooms. These rooms also have an additional single bed in each room. Downstairs has two additional bedrooms with attached two full bathrooms. One room has two single beds and the 4th bedroom has two bunk-beds with double beds below and single beds above. We also have another sleeper sofa and also a set of bunk-beds built into the wall in the main area downstairs. Please check out our flat rate prices for certain weekends and summer weeks.About pets:Pets allowed: dogs less than 50 lbs per pet (limit 2 pets total).Dogs only. Added $100 cleaning!.About checkOut:Check out before 10:00 AM.About children:Children allowed: ages 0-17.About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 25.About events:No events allowed.
Outstanding
36 reviews
9.8/10
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Beautiful home near Clemson Hotels in Seneca
Beautiful home near Clemson Hotels in SenecaBeautiful home near Clemson Hotels in SenecaBeautiful home near Clemson Hotels in SenecaBeautiful home near Clemson Hotels in SenecaBeautiful home near Clemson Hotels in SenecaBeautiful home near Clemson Hotels in Seneca
12
Hotels in Seneca
Convenient to anywhere you would like to be in our area. Less than a mile from shops, restaurants, breweries, Jazz on the Alley, and just 13 minutes away from Clemson University. This home is freshly remodeled throughout with new appliances, furniture, and tv’s as well.About pets:No pets allowed.About checkOut:Check out before 10:00 AM.About children:Children allowed: ages 0-17.About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 22.About events:No events allowed.
Amazing
5 reviews
9.4/10
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Quality Inn Seneca US-123 Hotels in Seneca
Quality Inn Seneca US-123 Hotels in SenecaQuality Inn Seneca US-123 Hotels in SenecaQuality Inn Seneca US-123 Hotels in SenecaQuality Inn Seneca US-123 Hotels in SenecaQuality Inn Seneca US-123 Hotels in SenecaQuality Inn Seneca US-123 Hotels in Seneca
88
Hotels in Seneca
Private parking
EV charging station
24-hour front desk
+4
"Room was clean and the bed linens smelled fresh. The front office staff and maids were all amiable and happy to be helpful. Breakfast was carb city. Did have self made hot waffles, muffins, cereals, yogurt bananas and coffee n juice. We stayed three nights and would be happy to go back."
Good
96 reviews
7.9/10
1 night
From AED 279
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Days Inn by Wyndham Seneca / Clemson Area Hotels in Seneca
Days Inn by Wyndham Seneca / Clemson Area Hotels in SenecaDays Inn by Wyndham Seneca / Clemson Area Hotels in SenecaDays Inn by Wyndham Seneca / Clemson Area Hotels in SenecaDays Inn by Wyndham Seneca / Clemson Area Hotels in SenecaDays Inn by Wyndham Seneca / Clemson Area Hotels in SenecaDays Inn by Wyndham Seneca / Clemson Area Hotels in Seneca
34
Hotels in Seneca
Private parking
EV charging station
Gym
+3
"It was ok, not bad. Would stay again definitely. Could work on amenities. No conditioner toothpaste. But overall it was a pleasure to have stayed"
96 reviews
6.9/10
1 night
From AED 251
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Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson! Hotels in Seneca
Renovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson! Hotels in SenecaRenovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson! Hotels in SenecaRenovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson! Hotels in SenecaRenovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson! Hotels in SenecaRenovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson! Hotels in SenecaRenovated Bungalow 1 Block from Downtown Seneca! 7 miles from Clemson! Hotels in Seneca
32
Hotels in Seneca
Golf course
Hiking
Wi-Fi in public areas
Step back in time in this renovated 1940 historic bungalow in downtown Seneca, SC. This charming 3BR, 1.5BA home sleeps 8 and is just steps from Ram Cat Alley's shops and dining. Enjoy a full kitchen, outdoor grill, fully fenced backyard, and a outdoor patio. Only 7 miles from Clemson University—ideal for families or Clemson visits. Close to Lake Keowee, Lake Jocassee, Lake Hartwell, waterfalls, hiking, and Chattooga River whitewater rafting. Your Seneca adventure awaits!**Prime Location:**Downtown Convenience: Steps from shopping, dining, bars, and tap rooms.Close to Clemson University: Only 8 miles away—perfect for game days!Nature at Your Doorstep: Minutes from Lakes Keowee, Jocassee, and Hartwell, plus scenic hiking trails.Golf Nearby: Oconee Country Club is just 3 miles away.**Home Amenities You'll Love:**Comfortable Stay: Three cozy bedrooms and 1.5 bathrooms.Modern Amenities: Fully equipped kitchen, big-screen TV, central AC, and free Wi-Fi.Outdoor Relaxation: Fenced backyard with patio and grill—perfect for unwinding.Ample Parking: Plenty of space for vehicles and boat trailers—ideal for adventure seekers.**Nearby Attractions & Activities:**Outdoor Adventures: Hiking, zip-lining, and whitewater rafting on the Chattooga River.Water Activities: Boating and fishing at Lakes Keowee, Hartwell, and Jocassee.Clemson Tiger Football: Experience the excitement just a short drive away.Community Events: Enjoy local charm with “Jazz on the Alley” from March to October.Book Now to make our charming bungalow your home base for exploring Seneca and Upstate South Carolina. Create unforgettable memories in this vibrant area! Note:Your safety matters. This property features a Ring doorbell device with an exterior security camera facing the front outdoor entry. The camera does not look into any interior spaces. The camera actively records video when motion is detected by the deviceAbout pets:Pets allowed: dogs (limit 2 total).About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 0-17.About customRules:Quiet Hours from 11:00 PM - 7:00 AM. No cats No additional guests or pets without prior approval..About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 18.About events:No events allowed.
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The Big Golf House- 10 miles to Clemson Hotels in Seneca
The Big Golf House- 10 miles to Clemson Hotels in SenecaThe Big Golf House- 10 miles to Clemson Hotels in SenecaThe Big Golf House- 10 miles to Clemson Hotels in SenecaThe Big Golf House- 10 miles to Clemson Hotels in SenecaThe Big Golf House- 10 miles to Clemson Hotels in SenecaThe Big Golf House- 10 miles to Clemson Hotels in Seneca
26
Hotels in Seneca
Wi-Fi in public areas
Welcome to your spacious golf course retreat in Seneca, South Carolina, just 15 minutes from Clemson University and minutes from Lake Keowee. This 4,700 sq ft, 4-bedroom, 4-bathroom home is perfect for Clemson football weekends, family gatherings, or lake getaways.Inside, you’ll find room for everyone with multiple living areas, large bedrooms, and four bathrooms. Entertainment is built in with a game room, bar, and private arcade, making the house just as fun to enjoy as the surrounding area. Start your mornings with coffee overlooking the course, and spend your evenings relaxing with family and friends in a private, peaceful setting.Guests love the quiet golf course atmosphere while still being close to everything: Lake Keowee marinas and boat rentals, hiking trails, local dining in downtown Seneca, and Clemson’s stadium.Whether you’re here for game day excitement, a lake adventure, or simply to unwind in a luxury vacation rental, this home combines space, comfort, and location in a way that makes every stay unforgettable.Note:Your safety matters. This property features a Ring doorbell device and flood light that have an exterior security camera facing the front outdoor entry. The camera does not look into any interior spaces. The camera actively records video when motion is detected by the deviceAbout pets:Pets allowed: dogs (limit 2 total).About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 0-17.About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 18.About events:No events allowed.
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FAQs About Seneca Hotels

What are the best places to stay in Seneca?

Some top places to stay in Seneca are near popular attractions like Bertha Lee Strickland Cultural Museum and South Cove County Park—so you can quickly get to top landmarks and amenities you need.

What hotels in Seneca offer an especially good breakfast?

Which hotels in Seneca provide fitness facilities?

Days Inn by Wyndham Seneca / Clemson Area (price from AED 239), Fairfield Inn & Suites Seneca Clemson Univ Area (price from AED 460) and Hampton Inn & Suites Seneca-Clemson Area (price from AED 400) include fitness facilities, so you can maintain your routine while traveling. Stay on track with your fitness goals while on the go!

Which hotels in Seneca have pools?

Days Inn by Wyndham Seneca / Clemson Area (price from AED 239), Best Western Seneca-Clemson (price from AED 352) and Fairfield Inn & Suites Seneca Clemson Univ Area (price from AED 460) are excellent options for hotels with swimming pools. Book your stay to enjoy the pool and make your trip more enjoyable.

What are the best hotels in Seneca near Bertha Lee Strickland Cultural Museum?

Some standout hotels in Seneca close to Bertha Lee Strickland Cultural Museum include Best Western Seneca-Clemson (price from AED 352), Fairfield Inn & Suites Seneca Clemson Univ Area (price from AED 460) and Days Inn by Wyndham Seneca / Clemson Area (price from AED 239), all within easy walking or transit distance of Bertha Lee Strickland Cultural Museum, perfect for travelers wanting to explore the landmark and its surroundings.

How to get good deals on hotels in Seneca?

Find the best hotel deals and promotions on Trip.com, available year-round for both first-time and loyal users. Please check the promotions page to see what promotions are available now on Trip.com.

Seneca Hotels Info

Number of Reviews
524
Total Properties
10
Weekday Avg. Price
AED 464
Weekend Avg. Price
AED 512