Jacksonville

Spa Hotels in Jacksonville

Top Jacksonville hotels with a serene luxury Spa.

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Guest Rating
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Jacksonville Spa Resorts & Hotels

Find premier Jacksonville hotels with therapeutic Spa.
Most Booked
Lowest price
Closest to downtown
Highest Rated
99+
Hotels in Jacksonville
Whether you're coming to Jacksonville for a visit to the Mayo Clinic or simply to enjoy the beach, the Holiday Inn Express & Suites Jacksonville SE – Med Center is your home away from home. Conveniently located just off Highway 202, J Turner Butler Blvd., our smoke-free hotel is only three miles from the Mayo Clinic campus. Relax in our spacious guest rooms, designed with your comfort and productivity in mind. Enjoy complimentary wifi, and unwind with a large-screen HDTV. The hotel is situated near major companies, including Allstate Insurance, Landstar, JP Morgan Chase, Windsor Parke Golf Course, and the University of North Florida (UNF). We are also just minutes from St. John’s Town Center—Jacksonville’s premier destination for upscale shopping and dining—as well as the beaches and Ponte Vedra, home to TPC Sawgrass and the annual PGA Tour Players Championship. For golf enthusiasts, you'll appreciate our unique location right on the 15th hole of Windsor Parke Golf Course. We offer a complimentary weekday shuttle to Mayo Clinic available Monday-Friday. If you're hosting an event, take advantage of our 1,250-square-foot meeting space. Stay active in our 24-hour fitness center or unwind in our partially covered outdoor pool featuring relaxing water elements. For dining options, you won’t have to go far—Ruby Tuesday, Publix, and Tropical Smoothie Café are just a few options within walking distance.

"Our stay was pretty great! The only negative was that the hot tub was out of service temporarily, but the pool made up for it. From the welcoming of the staff upon check in to check out, it was all up to par! I would highly recommend the hotel to anyone if they needed to stay close to the Mayo Clinic, etc.. it was Very convenient and reasonably priced."
Very Good
100 reviews
8.2/10
1 night
From US$105
Check availability
78
Hotels in Jacksonville
Welcome to the Holiday Inn Express® Hotel & Suites Jacksonville Blount Island!We’re delighted to have you with us and proud to offer you the absolute finest in Southern hospitality. Conveniently located just off Interstate 295 near the scenic St. Johns River, we are the closest hotel to the JAXPORT Carnival Cruise Ship Terminal—making us the perfect choice for cruise travelers. Whether you're here to set sail or simply explore, you'll love our location on Blount Island near top attractions like the Jacksonville Zoo, Kingsley Plantation, River City Marketplace, and just 16 miles from the stunning Huguenot Park and Beach.Our newly remodeled rooms were designed with your comfort in mind, offering a fresh, modern experience to help you relax and recharge. Enjoy thoughtful amenities like a complimentary hot breakfast bar, outdoor pool, and 24-hour fitness center.For corporate guests, our proximity to major businesses like TraPac, JEA, BAE Systems, APR Energy, and the shipyards makes us an ideal home base. Take advantage of our Business Center, free high-speed Wi-Fi, and a 644 sq. ft. meeting room—perfect for small gatherings of up to 30 people.Whether you're here for work or play, we look forward to making your stay exceptional.

"The front desk are always great and the hotels is so clean , quiet and convenient "
Very Good
103 reviews
8.5/10
1 night
From US$125
Check availability
99+
Hotels in Jacksonville
Discover a hotel in the heart of Florida’s largest city at Hampton Inn & Suites Jacksonville Deerwood Park. This Jacksonville hotel is less than ten minutes from downtown Jacksonville FL’s business, culture and family attractions. Indulge sporting passions from our Hampton Inn & Suites at the Jaguars’ EverBank Field, shooting the fairways of numerous local golf courses or hiking, boating and fishing 68 miles of Florida coastline. Relax in a luxurious guest room – they all have clean and fresh Hampton beds®. Upgrade to a spacious suite with space for the whole family - our Hampton Inn & Suites is a pet-friendly hotel with no supplementary charges for four-legged friends. Accessible rooms are designed for ease of movement. Stay connected from the comfort of your room with free high-speed internet access throughout this Jacksonville hotel. Host briefings for 12 in our boardroom and gatherings for 65 on the doorstep of Jacksonville in our St John’s conferencing room. Our terrace’s cascading water feature makes an elegant spot for breakout coffees and celebration drinks. Start the day right with Hampton’s free hot breakfast – choose your favorite toppings for oatmeal and fresh waffles to accompany hot and cold selections. Don’t miss out if you have early appointments – one of our free Hampton On the Run® Breakfast Bags, available Monday to Friday. Consult our local experts for inside info on the best Jacksonville FL restaurants.

"I’ve been staying here for the past couple weeks and experience has been great no complaints here so far thank you for the great service!!!!"
Great
95 reviews
9.0/10
1 night
From US$139
Check availability
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71
Hotels in Jacksonville
With close proximity to Jacksonville, Florida attractions including EverBank Stadium and the Jacksonville Zoo, the Holiday Inn Jacksonville E 295 Baymeadows is the ideal place to stay during your visit! Perfectly located on the East Loop of I-295 and Baymeadows Road, our Jacksonville hotel offers spacious guest rooms featuring great amenities as in-room microwave and refrigerator, free wired and wireless Internet access and a separate work area. Enjoy the convenience of our on-site lounge Burgers & Brews. Gather with friends for dinner or grab a drink at our Bar offering local beer, wine, and crafted drinks. Keep up your fitness routine in our 24-hour Fitness Center or bask in the Florida sun in our outdoor pool and patio. Take a stroll in Downtown Jacksonville or spend the day shopping at nearby St. Johns Town Center and The Avenues shopping mall. The business traveler will appreciate our 24-hour Business Center as well as the easy commute to the Mayo Clinic and University of North Florida. Our hotel hosts the largest conference and banquet space in the Jacksonville Baymeadows area. The City Grand Event Center offers a 4,000 sq. ft. meeting facility making it the ideal event venue for your next corporate meeting or social function. Let our hotel in Jacksonville make you feel at home each time and every time.

"The staff is always friendly and helpful The rooms are clean The location is perfect "
Very Good
100 reviews
8.6/10
1 night
From US$101
Check availability
99+
Hotels in Jacksonville
With a stay at Country Inn & Suites by Radisson, Jacksonville West, FL in Jacksonville (Northwest), you'll be within a 15-minute drive of VyStar Veterans Memorial Arena and Jacksonville Naval Air Station. This hotel is 9.6 mi (15.5 km) from EverBank Stadium and 10.7 mi (17.2 km) from Jacksonville Zoo and Gardens. Take advantage of recreation opportunities including an outdoor pool and a 24-hour fitness center. This hotel also features complimentary wireless internet access, a fireplace in the lobby, and a banquet hall. Satisfy your appetite at the hotel's coffee shop/cafe, or stay in and take advantage of the room service (during limited hours). A complimentary buffet breakfast is served on weekdays from 6:00 AM to 9:00 AM and on weekends from 7:00 AM to 10:00 AM. Featured amenities include complimentary wired internet access, a business center, and complimentary newspapers in the lobby. Free self parking is available onsite. Make yourself at home in one of the 73 air-conditioned rooms featuring refrigerators and microwaves. Wired and wireless internet access is complimentary, while 55-inch flat-screen televisions with cable programming provide entertainment. Private bathrooms have complimentary toiletries and hair dryers. Conveniences include desks and coffee/tea makers, as well as phones with free local calls.

"The facilities were excellent. Check in was great and when I asked for a late check out it was no problem accommodating my request. Did not get to eat breakfast came in at the tail end of it but I did enjoy my cup of coffee. "
Good
97 reviews
7.7/10
1 night
From US$123
Check availability
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Frequently Asked Questions

What are the best hotels with Spa in Jacksonville?

How much does it cost to stay in Jacksonville hotels with Spa?

For hotels with Spa in Jacksonville, the average price on weekdays is US$179, and the average price on weekends (Friday - Saturday) is US$188.

What are the best hotel deals for Jacksonville hotels with Spa?

Trip.com offers great travel deals all year long. Visit the promotions page to find the latest discounts and special offers on Trip.com.

Jacksonville Hotels with Spa Information

Total Properties5
Number of Reviews 493
Weekday Avg. PriceUS$179
Weekend Avg. PriceUS$188