Best Hotels in O'Fallon, United States – Compare Prices, Reviews & Book Online

> The Holiday Inn Express Hotel & Suites in O'Fallon, MO is located just west of St. Louis. Our hotel is convenient to Interstate 64 and is near several local attractions and businesses making it the perfect hotel for travelers looking for lodging in O'Fallon. Our O’Fallon hotel is conveniently located near major businesses including Citi, General Motors, Mastercard, APC, Nortek, the Missouri Research Park, and Progress West Hospital, making us an ideal choice for business travelers. When it’s time to relax, you’ll find plenty of fun nearby. We’re just minutes from historic St. Charles, Six Flags St. Louis, and the O’Fallon Sports Complex. And with downtown St. Louis only a short drive away, you can easily explore iconic attractions like the Gateway Arch, Anheuser-Busch Brewery, Laclede’s Landing, and cheer on the Cardinals or the Blues at their home stadiums. Whether you’re here for meetings or memories, our location puts the best of St. Louis within easy reach. Bring the whole family—even the four-legged ones! Our pet-friendly O’Fallon hotel features a heated indoor pool, modern fitness center, and our free Express Start™ breakfast bar with favorites like fresh coffee and signature cinnamon rolls. Explore our latest deals and book your stay today.

Welcome to Staybridge Suites - O'Fallon/Chesterfield. Featuring apartment-style suites ideal for vacationing families and those in town for business. Staybridge Suites ® O'Fallon MO hotel is designed for the discerning traveler. Conveniently located near the intersection of Hwy 40 and Highway K, we offer the best accommodations for your travel. Our all-suite hotel is great for visiting local companies and institutions: Mastercard, Citi. After a long day at work, come relax in your spacious suite equipped with a full kitchen, plush bedding and a flexible workspace. Stay connected with our free Wi-Fi access throughout the hotel. Leisure travelers enjoy shopping at local outlet malls or trying their luck at Ameristar or Harrah's casinos. Our hotel is also located near historic St. Charles, Hollywood Casino Amphitheater, Gateway Arch and the St. Louis Cardinals' stadium. After a day of adventure, come back to your hotel suite and take advantage of all the thoughtful amenities that our hotel provides. During your extended stay, indulge in our evening social Mon-Wed with complimentary dinner, soft drinks, beer and wine. We also offer a complimentary breakfast, guest laundry facilities, Fitness Center, Business Center and outdoor pool. We offer plenty of space and privacy, with fully stocked kitchens, microwaves, full size refrigerators and dishes. Pets are also welcome for an additional fee. Allow us to be your home away from home!