Rochester

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Compare Best 4-Star Hotels in Rochester with Prices & Reviews

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Most Booked
Lowest price
Closest to downtown
Highest Rated
99+
Hotels in Rochester
No. 3 of 4-Star Select Hotels in Minnesota
The Hilton Rochester Mayo Clinic Area is located in downtown Rochester two blocks from Mayo Clinic and one block from the Mayo Civic Center. Rochester International Airport is 8 miles away with flights to Chicago and Minneapolis. Minneapolis St. Paul International Airport is 80 miles away with frequent shuttle service. Interstate 90 is also 8 miles from downtown providing access from Madison, Chicago, and points east. The hotel offers spacious guest rooms and suites with Hilton bedding, work areas, seating, and free high speed internet. WiFi is available throughout and a Tech Lounge is located in the lobby. The fifth floor holds an indoor infinity pool, steam room, sauna, and outdoor rooftop terrace. Hilton Honors Gold members receive complimentary breakfast in the lounge and upgrades based on availability. Hilton Honors Diamond members receive complimentary lounge access and upgrades based on availability. Seven luxury suites are located on the top floor offering expansive accommodations with enhanced amenities. Guests in these suites have access to a dedicated concierge team providing personalized assistance with dining, transportation, and local arrangements for an elevated stay experience. The event center provides 24,000 sq. ft. of meeting and banquet space including two ballrooms with 19-foot ceilings, breakout rooms, and pre-function areas. Facilities feature modern audiovisual equipment and catering services for conferences, seminars, weddings, and receptions, with panoramic city views. The hotel connects to the city skyway system offering climate-controlled access to Mayo Clinic, Galleria at University Square mall, restaurants, the University of Minnesota Rochester campus, the Courthouse, and other downtown locations. Hilton Rochester Mayo Clinic Area combines a central location with contemporary design and personalized service for medical, business, and leisure travelers.

"Very convenient and quiet, convenient transportation, walk to the main Mayo building 10-15 minutes. You can walk through skyway. The two restaurants that come with them are delicious and the service is good."
Amazing
109 reviews
9.4/10
Check availability
46
Hotels in Rochester
A stay at The Towers At Kahler Grand Hotel places you in the heart of Rochester, a short 4-minute walk from Mayo Clinic and within 2 minutes by car from Mayo Clinic Hospital - Saint Marys Campus. This hotel is 0.1 mi (0.2 km) from Shops University Square and 0.2 mi (0.4 km) from University of Minnesota-Rochester. Take advantage of recreation opportunities including an indoor pool and a fitness center. Additional amenities at this hotel include complimentary wireless internet access, concierge services, and gift shops/newsstands. Enjoy American cuisine at Lord Essex Tavern & Grill, one of the hotel's 2 restaurants, or stay in and take advantage of the room service (during limited hours). Snacks are also available at the coffee shop/cafe. Mingle with other guests at the complimentary reception, held daily. Quench your thirst with your favorite drink at the bar/lounge. A complimentary self-serve breakfast is served daily from 6:00 AM to 9:00 AM. Featured amenities include a business center, dry cleaning/laundry services, and a 24-hour front desk. Free valet parking is available onsite. Stay in one of 44 guestrooms featuring plasma televisions. Your bed comes with down comforters and premium bedding. Complimentary wireless internet access keeps you connected, and digital programming is available for your entertainment. Bathrooms feature showers, designer toiletries, and hair dryers.
Amazing
59 reviews
9.5/10
Check availability
99+
Hotels in Rochester
Discover an elevated hotel experience at EVEN Hotel Rochester - Mayo Clinic Area. Settle into a comfortable, restorative stay with our thoughtful amenities and inviting rooms. Our hotel in Rochester, Minnesota, is perfectly positioned near Rochester International Airport and the Mayo Clinic, offering easy access for patients, visitors, and guests alike.  At our downtown Rochester hotel, you're never far from where you need to be. Visit local favorites such as the Rochester Art Center and the University of Minnesota Rochester. Immerse yourself in Rochester's natural beauty at Quarry Hill Nature Center, Douglas State Trail, and Chester Woods Park. Business travelers will appreciate the convenience of being just moments from IBM's Rochester Technology campus. Relax in our premium guestrooms, featuring free Wi-Fi, plush bedding, and spa-like bathrooms. Enjoy a delicious meal at EVEN Kitchen & Bar or pick up snacks and essentials from our 24/7 market. Take advantage of our state-of-the-art Athletic Studio and our complimentary door-to-door shuttle service to the Mayo Clinic. Recharge, unwind, and leave feeling uplifted at EVEN Hotel Rochester - Mayo Clinic Area.

"This is a wonderful long-term stay hotel. Its greatest advantage over other hotels in the Mayo Clinic area is the friendliness and competence of the staff. every single one of the staff that I’ve interacted with was superb. Most four-star hotels don’t have this level of service that I’ve experienced at StayBridge the breakfast buffet is very good. The restaurant is outstanding. The staff at the reception desk is more competent and nicer than any hotel I can think of in Minnesota It is across the entrance from Mayo St. Mary’s Hospital Also there are several very good restaurants within two blocks in each direction I’ve stayed in four other hotels in the three years that I receive care at Mayo Clinic and this one is fairly superior to the others. Dr. Stefan Bracha MD A Mayo patient from Honolulu"
Great
105 reviews
9.3/10
Check availability
97
Hotels in Rochester
Directly connected to the Mayo Clinic, Rochester Marriott Mayo Clinic Area, hotel offers easy access to some of the city's most popular attractions via underground climate-controlled pedestrian walkways and skyways. Shop at University Square and enjoy biking, running and several trails nearby. Or visit Minneapolis and Saint Paul, an easy day trip from Rochester, MN. Host an event or board meeting in our hotel's modern venues or unwind after a busy day at our in new in house restaurant North Stone Kitchen. Business travelers, enjoy spacious guest rooms with work areas and Wi-Fi. All our guest rooms and suites feature luxurious bedding and HDTVs, plus a wealth of upscale amenities. Find modern luxury downtown Rochester at Rochester Marriott Mayo Clinic Area.

"It is very convenient to go to Mayo, and it is also the reason why the price is expensive. The underground and the 2nd floor corridor can pass, avoiding the cold in winter. The front desk is welcoming, the hotel cleaning is very sloppy, the tea is not replenished, the garbage is not taken away, and the tip is taken diligently."
Very Good
93 reviews
8.3/10
Check availability
24
Hotels in Rochester
Charming home 1 block from St. Marys Hospital, Rochester, MN. Features 4 bedrooms (3 king, 1 full), each with wall-mounted TVs, and 2 full baths. Fully equipped kitchen, separate dining room seating 8, and cozy living room with Italian leather sectional and wood-burning fireplace. New outdoor patio with 8-seat dining set and Weber grill. Brand-new heating and A/C for year-round comfort. Perfect for families, groups, or extended stays.The spaceThank you for clarifying! Here’s the revised description without mentioning Twigs:---Here’s an updated, in-depth description with all the details:---Welcome to your perfect Rochester retreat, located just a block from St. Marys Hospital. This charming 4-bedroom home offers spacious, stylish accommodations with comfort and convenience in every detail, ideal for families, groups, or extended stays.Each bedroom is thoughtfully appointed to create a restful retreat. Three of the bedrooms are located on the second floor: two feature luxurious king beds with 65-inch TVs, while the third upstairs bedroom has a full bed with a 55 inch TV. The fourth bedroom, located on the ground floor, has a cozy king bed and a 32-inch TV for convenience.The fully equipped kitchen is stocked with all essentials, whether you’re whipping up a quick breakfast or a family dinner. With plenty of dishes, cookware, and utensils, this kitchen is ready for everything from casual cooking to special meals. The dining room, which seats eight comfortably, is separate from the kitchen, offering an inviting space for group meals, game nights, or gatherings.The living room is a comfortable space to relax, featuring a luxurious Italian leather sectional by Natuzzi, soft area rugs, and a warm wood-burning fireplace that adds an inviting touch. Wood floors add elegance, and the layout makes it perfect for unwinding with family or friends.For outdoor enjoyment, step out onto the new concrete patio equipped with an 8-seat dining set and a Weber grill, perfect for summer barbecues or sipping morning coffee while taking in the fresh Minnesota air. Central heating and a brand-new air conditioning system keep the entire home cozy and comfortable, no matter the season.For tech amenities, enjoy high-speed internet and YouTube TV in every room. Additionally, the spacious driveway provides free parking for up to four cars, making it convenient for larger groups. For guests visiting the Mayo Clinic, the convenience is unbeatable: you can walk or take the free shuttle from St. Marys Hospital, eliminating the need to pay for Mayo parking.Within walking distance, you’ll find popular restaurants like Canadian Honker, known for its comforting American fare and welcoming atmosphere—a Rochester favorite for all meals. Red Cow is extremely close and offers gourmet burgers and craft beers in a lively, laid-back setting, perfect for a fun night out. For lighter, fresh options, Salad Brothers Cafe & Deli serves up delicious salads, soups, and sandwiches, making it ideal for a quick, healthy meal between appointments or explorations.This Rochester home is perfectly designed for both comfort and convenience, offering you an ideal balance of privacy, amenities, and prime location. Whether you’re here for a medical visit, business, or leisure, this home provides a welcoming, fully equipped base. Book now to enjoy a stay that feels like home in the heart of Rochester!Guest accessA door code will be given to the guest shortly before arrival.About pets:No pets allowed.About checkOut:Check out before 10:00 AM.About children:Children allowed: ages 0-17.About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 30.About events:No events allowed.
Outstanding
14 reviews
10/10
Check availability
18
Hotels in Rochester
Welcome to our Mynt House, our serene haven 7 mins away from Mayo Clinic, just a short walk from the tranquil Silver Lake and shopping. This mid-century fully furnished modern gem is designed for your ultimate comfort. Enjoy the office space, TV entertainment, blasting fast Internet, washer/dryer & fully equipped kitchen for cooking. We offer one king size bed, one queen bed, 2 full size beds and one twin-size bed. Thoughtfully updated to provide a space that feels like home during your stay. Spacious. Stylish. Super comfortable.Enjoy 4 thoughtfully designed bedrooms, including a king bed, queen bed, two full beds, and a twin, perfect for families, caregivers, or business travelers needing space and rest. With a dedicated office space, ultra-fast Wi-Fi, smart TVs with streaming, and a fully equipped kitchen, you’ll have everything you need for short or extended stays.Top Features:- Prime location: 7 mins to Mayo Clinic / Saint Marys Hospital- 4 bedrooms / 5 beds for ultimate flexibility - 1 full bathroom with bidet (a must-have for many guests!) - Washer & dryer in unit- Keurig coffee station - High-speed internet + Netflix, Disney+, Chromecast- Fresh linens, towels, bathroom essentials- Self check-in & digital home guide- Free private parking- No shared spaces – entire home is yoursBedroom Layout:- Bedroom 1: Queen bed - Bedroom 2: Two Full beds - Bedroom 3: King bed - Bedroom 4: Twin bed Guest Experience:From the moment you book, you’ll receive a warm welcome via text and email, along with a link to our digital home guide, your go-to for Wi-Fi info, check-in instructions, house rules, and our favorite local spots for food, coffee, and shopping. We’re always just a message away to assist you throughout your stay.Why Guests Love Us:- Impeccable cleanliness and comfort - Quiet, safe neighborhood - Easy access to Mayo, dining, and scenic trails - Superhost-level care and attentionWhether you're in town for a short visit or an extended medical stay, Mynte House offers peace, convenience, and modern comfort—just minutes from the heart of Rochester.Book your stay today—homes like this near Mayo book FAST!About pets:No pets allowed.About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 0-17.About checkIn:Check in after 3:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 18.About events:No events allowed.
Amazing
9.6/10
Check availability
24
Hotels in Rochester
This charming, spacious 3-bedroom home is located in a quiet neighborhood, just 9 minutes from downtown and the Mayo Clinic. Ideal for families, it offers plenty of space to relax and unwind. Enjoy movie nights with three 80" smart TVs, spacious walk-in closets, 3 fireplaces, and a calming sauna. The modern kitchen is equipped with top-of-the-line appliances, and you can take in beautiful city views. With all the essential amenities, this home provides a comfortable, family-friendly environment.About pets:No pets allowed.About checkOut:Check out before 11:00 AM.About children:Children allowed: ages 0-17.About customRules:No parties, events, or gatherings of any kind.About checkIn:Check in after 3:00 PM.About smoking:Smoking is not permitted.About minBookingAge:Minimum age to rent: 21.About events:No events allowed.
Outstanding
4 reviews
10/10
Check availability
16
Hotels in Rochester
Minutes away from downtown shops, restaurants, and Mayo Clinic, this newly renovated main-level duplex home is cheerful and ready for your arrival. The open living/dining area feels spacious and bright, with two picture windows letting in lots of natural light. Big-screen Smart TV--sign into your accounts on apps such as Netflix, Amazon Video, or Hulu to view your favorite shows and movies.Enjoy two private bedrooms, each with a queen-sized bed. The master bedroom includes a full bath ( tub, shower, vanity and tub). There is also a half bath ( vanity & toilet) in the apartment.Fully-equipped kitchen makes for efficient cooking and baking. 10-cup coffee maker, Keurig machine, blender, and toaster, to name a few.The bus stop is less than a block away. Nearby biking/walking paths lead you through the city, along the creek, anywhere you want to explore.From May-October, visit the local Farmer's Market at Graham Park.About pets:No pets allowed.About checkOut:Check out before 11:00 AM.About children:Adults only.About checkIn:Check in after 4:00 PM.About smoking:Smoking is not permitted.About events:No events allowed.
Amazing
18 reviews
9.4/10
Check availability
24
Hotels in Rochester
This Home Features Main Floor Bed/Bath!!Enjoy your stay at this bright and charming 3-bedroom Main Floor home, just steps from Mayo Clinic! This clean, comfortable space features 3 bedrooms, a full bathroom, a cozy living room with a recliner, and a fully stocked kitchen with a dining area. Enjoy the private patio and off-street parking. Unbeatable convenience at this ideally located home—just blocks from Mayo Clinic and directly across from the Groom shuttle stop. Skip the stress of construction and traffic with an easy one-minute drive to the Gonda, Methodist, Charlton, or Jacobson buildings downtown. Whether you’re here for appointments or a longer stay, this location makes every visit simple, smooth, and worry-free.About pets:No pets allowed.About children:Children allowed: ages 0-17.About smoking:Smoking is not permitted.About events:No events allowed.
Outstanding
4 reviews
10/10
Check availability
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Frequently Asked Questions

How much does a 4 star hotel cost in Rochester?

For 4 star hotels in Rochester, the average price on weekdays is CAD 758, the average price on weekends (Friday–Saturday) is CAD 682.

What are the best 4 star hotels with pools in Rochester?

Which 4 star hotels in Rochester have fitness centre?

What are the best 4 star hotels in Rochester with bars?

Which 4 star hotels in Rochester offer great breakfasts?

What are the best 4 star spa hotels in Rochester?

What are the best 4 star hotels in Rochester with free Wi-Fi?

What are the best deals for 4 star hotels in Rochester?

Trip.com offers promotions and deals for 4 star hotels. You can visit the promotions page to find out what offers are available on Trip.com.

Hotel Info for Tourists

Highest PriceCAD 667
Lowest PriceCAD 667
Number of Reviews 398
Total Properties9
Weekday Avg. PriceCAD 758
Weekend Avg. PriceCAD 682